Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Andrew D. Fesnak"'
Autor:
Andrew D. Fesnak, Don L. Siegel
Publikováno v:
Rossi's Principles of Transfusion Medicine. :633-641
Autor:
Barbara Savoldo, Gerhard Bauer, Brian G. Till, Peter Marks, Helen E. Heslop, Andrew D. Fesnak, Steven A. Feldman, Magdi Elsallab, Mohamed Abou-el-Enein
Supplementary Data from Scalable Manufacturing of CAR T Cells for Cancer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c9f72194e95c7d56059a0c2e79e392
https://doi.org/10.1158/2643-3230.22543887
https://doi.org/10.1158/2643-3230.22543887
Autor:
Barbara Savoldo, Gerhard Bauer, Brian G. Till, Peter Marks, Helen E. Heslop, Andrew D. Fesnak, Steven A. Feldman, Magdi Elsallab, Mohamed Abou-el-Enein
As of April 2021, there are five commercially available chimeric antigen receptor (CAR) T cell therapies for hematologic malignancies. With the current transition of CAR T cell manufacturing from academia to industry, there is a shift toward Good Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e38dcc00964eaa1f4ed05f6ec5f92e
https://doi.org/10.1158/2643-3230.c.6550449
https://doi.org/10.1158/2643-3230.c.6550449
Publikováno v:
Successful Drug Discovery
Autor:
Andrew D. Fesnak, Anne Lamontagne
Publikováno v:
Cell and Gene Therapy Insights. 6:157-1363
Autor:
Magdi Elsallab, Gerhard Bauer, Steven A. Feldman, Helen E. Heslop, Brian G. Till, Andrew D. Fesnak, Mohamed Abou-El-Enein, Barbara Savoldo, Peter W. Marks
Publikováno v:
Blood Cancer Discov
As of April 2021, there are five commercially available chimeric antigen receptor (CAR) T cell therapies for hematologic malignancies. With the current transition of CAR T cell manufacturing from academia to industry, there is a shift toward Good Man
Autor:
Pamela A Shaw, Don L. Siegel, Andrew D. Fesnak, Christina Fasano, Kelly D. Getz, Richard Aplenc, Jennifer Brogdon, Amanda M. DiNofia, Allison Barz Leahy, Yimei Li, Megan M. Davis, Diane Baniewicz, Hongyan Liu, Lisa Wray, Carl H. June, David T. Teachey, Elizabeth O. Hexner, Stephan A. Grupp, Edward Pequignot, Bruce L. Levine, Colleen Callahan, Simon F. Lacey, Shannon L. Maude, Gerald Wertheim, Anne Chew, Chelsie Bartoszek, Regina M. Myers, Susan R. Rheingold, David M. Barrett
Publikováno v:
J Clin Oncol
PURPOSE CD19-targeted chimeric antigen receptor (CAR)–modified T cells demonstrate unprecedented responses in B-cell acute lymphoblastic leukemia (B-ALL); however, relapse remains a substantial challenge. Short CAR T-cell persistence contributes to
Autor:
Chip White, Reid Bishop, Andrew D. Fesnak, Junxuan Li, Ben Wang, Linda Ho, Kan Wang, Amritava Das, Aaron D. Levine, Yi Liu, Bruce L. Levine
Publikováno v:
Cytotherapy. 21:1081-1093
Background aims Autologous cell therapy (AuCT) is an emerging therapeutic treatment that is undergoing transformation from laboratory- to industry-scale manufacturing with recent regulatory approvals. Various challenges facing the complex AuCT manufa
Autor:
Andrew D. Fesnak
Publikováno v:
Regen Eng Transl Med
Autologous Chimeric Antigen Receptor (CAR) T cell manufacturing involves the modification and expansion of T cells obtained by apheresis collection from a patient. The mechanism of apheresis collection and the specific clinical features seen in these
Autor:
Andrew D. Fesnak, Ryan J. Golden
Publikováno v:
Transfus Apher Sci
Both natural killer (NK) cells and T cells demonstrate potent antitumor responses in many settings. NK cells, unlike T cells, are not the primary mediators of graft-versus-host disease (GVHD). Redirection of T cells with chimeric antigen receptors (C