Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew D. Farr"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionBacterial strains that are resistant to antibiotics may protect not only themselves, but also sensitive bacteria nearby if resistance involves antibiotic degradation. Such cross-protection poses a challenge to effective antibiotic therapy
Externí odkaz:
https://doaj.org/article/77a6e853c5b4472bbee89f010c2a7dd6
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Adaptive evolutionary processes are constrained by the availability of mutations which cause a fitness benefit and together make up the fitness landscape, which maps genotype space onto fitness under specified conditions. Experimentally deri
Externí odkaz:
https://doaj.org/article/2f650e2fd6ce4b52a2389a9fd50f6468
Autor:
Lukas Geyrhofer, Philip Ruelens, Andrew D. Farr, Diego Pesce, J. Arjan G. M. de Visser, Naama Brenner
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT A common strategy used by bacteria to resist antibiotics is enzymatic degradation or modification. This reduces the antibiotic threat in the environment and is therefore potentially a collective mechanism that also enhances the survival of n
Externí odkaz:
https://doaj.org/article/a86d073a0a444c1cb67ddc457d60eb0c
Publikováno v:
Journal of Molecular Evolution.
In recent years, evolutionary biologists have developed an increasing interest in the use of barcoding strategies to study eco-evolutionary dynamics of lineages within evolving populations and communities. Although barcoded populations can deliver un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d09e3f29bf38f688f4536d6fd502a70a
https://doi.org/10.1007/s00239-023-10103-6
https://doi.org/10.1007/s00239-023-10103-6
In recent years evolutionary biologists have developed increasing interest in the use of barcoding strategies to study eco-evolutionary dynamics of lineages within evolving populations and communities. Although barcoded populations can deliver unprec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4273f9c82c1f813d40f848593c796d9
https://doi.org/10.1101/2022.09.30.510243
https://doi.org/10.1101/2022.09.30.510243
Autor:
Lukas Geyrhofer, Philip Ruelens, Andrew D. Farr, Diego Pesce, J. Arjan G.M. de Visser, Naama Brenner
A common strategy used by bacteria to resist antibiotics is enzymatic degradation or modification. Such a collective mechanism also enhances the survival of nearby cells, an effect that increases with the number of bacteria that are present. Collecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f61a9b8655447191d65fd59f2a35e7a
https://doi.org/10.1101/2022.08.04.502802
https://doi.org/10.1101/2022.08.04.502802
Adaptive evolutionary processes are constrained by the availability of mutations which cause a fitness benefit – a concept that may be illustrated by ‘fitness landscapes’ which map the relationship of genotype space with fitness. Experimentally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d11eab66b2564014b368e19cbce34c61
https://doi.org/10.1101/2022.07.13.499905
https://doi.org/10.1101/2022.07.13.499905
Publikováno v:
eLife, Vol 4 (2015)
Replicate populations of natural and experimental organisms often show evidence of parallel genetic evolution, but the causes are unclear. The wrinkly spreader morph of Pseudomonas fluorescens arises repeatedly during experimental evolution. The muta
Externí odkaz:
https://doaj.org/article/4e455c31dd594cb69ce03c120d61312e
Publikováno v:
Nature Ecology & Evolution 1 (2017) 10
Nature Ecology & Evolution, 1(10), 1562-1568
Nature Ecology & Evolution
Nature Ecology & Evolution, 1(10), 1562-1568
Nature Ecology & Evolution
Knowledge of adaptive processes encompasses understanding the emergence of new genes. Computational analyses of genomes suggest that new genes can arise by domain swapping; however, empirical evidence has been lacking. Here we describe a set of nine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008b2e6b878b3d4ad186ae701f8c3919
https://doi.org/10.1038/s41559-017-0283-7
https://doi.org/10.1038/s41559-017-0283-7
Publikováno v:
The ISME Journal
Model microbial systems provide opportunity to understand the genetic bases of ecological traits, their evolution, regulation and fitness contributions. Experimental populations of Pseudomonas fluorescens rapidly diverge in spatially structured micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f191b8354ec72de4f87ad580b0103067
https://doi.org/10.1038/ismej.2016.157
https://doi.org/10.1038/ismej.2016.157