Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrew D. Blair"'
Autor:
Gordon J. Conard, Steven C. Forland, Ellen Burgess, Ralph E. Cutler, Charles E. Weeks, J. M. Fox, Andrew D. Blair, Donald C. Kvam
Publikováno v:
The Journal of Clinical Pharmacology. 28:259-267
The pharmacokinetics of flecainide acetate were studied in 20 patients with varying degrees of renal impairment following a single oral dose. The patients were divided into two groups, on the basis of renal creatinine clearance (CLCR), for statistica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57a1d82206ce54a4d94d5b8fb03494c
https://doi.org/10.1002/j.1552-4604.1988.tb03142.x
https://doi.org/10.1002/j.1552-4604.1988.tb03142.x
Publikováno v:
Clinical Pharmacology & Therapeutics. 22:395-401
Furosemide kinetics were studied in 4 normal subjects after single intravenous injections (1 mg/kg). One experiment was done after pretreatment with probenecid. The apparent volume of furosemide distribution was unchanged after probenecid (10.9 L). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44224760938870d51528857fdc93166
https://doi.org/10.1002/cpt1977224395
https://doi.org/10.1002/cpt1977224395
Autor:
B M Maxwell, M A O'Neill, Arden W. Forrey, Ralph E. Cutler, B T Meijsen-Ludwick, Andrew D. Blair
Publikováno v:
Toxicology and Applied Pharmacology. 44:453-462
The relative nephrotoxicities of the gentamicin complex (Garamycin) and gentamicin C 1 were studied using “acute” (intravenous infusion, five normal renal function subjects) and 3-day (multiple injections for 3 days, five normal renal function su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43947abe3348560e53336b55562bd7a0
https://doi.org/10.1016/0041-008x(78)90253-3
https://doi.org/10.1016/0041-008x(78)90253-3
Publikováno v:
Clinical Pharmacology and Therapeutics. 29:457-463
Kinetics of sotalol, a beta adrenoceptor blocker, was studied in 20 patients with varying renal function. In subjects with creatinine clearance (Clcr) ≥ 39 ml/min/m2, sotalol plasma clearance (x ± SD) was 71 ± 31 ml/min/m2, elimination half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4c0baa95b7eeccd93e731c8adbc2b5
https://doi.org/10.1038/clpt.1981.63
https://doi.org/10.1038/clpt.1981.63
Publikováno v:
Clinical Pharmacology & Therapeutics. 25:514-521
Kinetic parameters and bioavailability of cefadroxil were studied in 20 subjects with differing renal function as measured by endogenous creatinine clearance (CCr). Two subjects were on hemodialysis. After an overnight fast, each subject ingested two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9bfe5b26e3f9f9528ce335bb2edf16
https://doi.org/10.1002/cpt1979255part1514
https://doi.org/10.1002/cpt1979255part1514
Autor:
Andrew D. Blair, Ralph E. Cutler
Publikováno v:
Clinical Pharmacokinetics. 4:279-296
Frusemide is an anthranilic acid derivative that is pharmacologically more potent than organomercurial agents in producing natriuresis and is effective when taken orally even in acid-base disorders or advanced renal failure. The bioavailability of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5fb6d2458bfd904b1a7381c3fec8ec
https://doi.org/10.2165/00003088-197904040-00002
https://doi.org/10.2165/00003088-197904040-00002
Publikováno v:
Kidney and Blood Pressure Research. 5:27-30
The renal clearance of inulin (Clin), 14C-creatinine (Cl14C.cr) and endogenous creatinine (Clcr) were measured in 6 healthy subjects before and after a single intravenous bolus of cimetidine (5 mg/kg). The initial Cli4C.cr/Clin ratio (mean ± SD) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e2feef4178221a39a417d11201b20f
https://doi.org/10.1159/000172836
https://doi.org/10.1159/000172836
Autor:
Joseph C. Stothert, Mary Farley, Andrew D. Blair, David A. Simonowitz, Ralph E. Cutler, E. P. Dellinger, William H. Edwards, C. Carrico
Publikováno v:
Annals of Surgery. 192:169-174
One hundred forty-four critically ill patients admitted to an intensive care setting were randomly assigned to cimetidine or antacid treatament groups. Gastric pH was monitored hourly. One hundred twenty-three (85%) patients demonstrated a fall in pH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97659fb02cc6233b11e64a60ff7bfc6f
https://doi.org/10.1097/00000658-198008000-00006
https://doi.org/10.1097/00000658-198008000-00006
Publikováno v:
Journal of Infectious Diseases. 134:S323-S330
The acetylating radioenzymatic assay was used for determination of levels of amikacin in serum and urine. Because of an inhibitor present in various amounts in urine, assay of amikacin in urine by this method requires added internal standards and thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c8e685fc25709a2ecefe8b9da6dc29
https://doi.org/10.1093/infdis/135.supplement_2.s323
https://doi.org/10.1093/infdis/135.supplement_2.s323
Publikováno v:
Clinical Chemistry. 20:152-158
We describe a modification of the fluorometric method of Häussler and Hajdú [Arzneim. Forsch. 14, 704 and 709 (1964)] for assay of furosemide in either serum or urine. A 1-ml sample, acidified to pH 2, is extracted with 5 ml of diethyl ether; 4 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a82e99660f941c00391757470e5f2c
https://doi.org/10.1093/clinchem/20.2.152
https://doi.org/10.1093/clinchem/20.2.152