Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew D. Biancolin"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted by the intestinal L cell in response to nutrient intake. However, GLP-1 secretion also follows a circadian rhythm which is disrupted by the saturated fatty acid palmitate in vi
Externí odkaz:
https://doaj.org/article/554a69a92f394ceb889a286852583454
Autor:
Andrew D. Biancolin, Alexandre Martchenko, Emilia Mitova, Patrick Gurges, Everan Michalchyshyn, Jennifer A. Chalmers, Alessandro Doria, Josyf C. Mychaleckyj, Alice E. Adriaenssens, Frank Reimann, Fiona M. Gribble, Manuel Gil-Lozano, Brian J. Cox, Patricia L. Brubaker
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 124-137 (2020)
Objectives: The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted from intestinal L-cells upon nutrient intake. While recent evidence has shown that GLP-1 is released in a circadian manner in rats, whether this occurs in mice and if this p
Externí odkaz:
https://doaj.org/article/f6ff2737afcd47bc877a504901b598cc
Autor:
Sarah E. Martchenko, Alexandre Martchenko, Andrew D. Biancolin, Alison Waller, Patricia L. Brubaker
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101340- (2021)
Objective: Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism throug
Externí odkaz:
https://doaj.org/article/b12602626be544f7a8428e51c6fa81a9
Publikováno v:
Endocrinology. 163
Metabolism and circadian rhythms are intimately linked, with circadian glucagon-like peptide-1 (GLP-1) secretion by the intestinal L-cell entraining rhythmic insulin release. GLP-1 secretion has been explored in the context of obesogenic diets, but n
Autor:
Patricia L. Brubaker, Alexandre Martchenko, Alison S. Waller, Andrew D. Biancolin, Sarah E. Martchenko
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101340-(2021)
Molecular Metabolism, Vol 54, Iss, Pp 101340-(2021)
Objective Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism through
Publikováno v:
Diabetes. 70
The intestinal L-cell hormone Glucagon-like Peptide-1 (GLP-1) increases glucose-dependent insulin secretion and is thus used in the treatment of T2D. GLP-1 secretion from the L-cell exhibits a circadian pattern in rodents and varies by time-of-day in
Publikováno v:
Diabetes. 70
Glucagon-like peptide-1 (GLP-1) is an incretin hormone released by the intestinal L cell in response to nutrient intake. Recent studies identified a circadian rhythm in GLP-1 secretion that is disrupted in whole-body Bmal1 KO mice. However, the exten
Autor:
Andrew D. Biancolin, Patrick Gurges, Manuel Gil-Lozano, Brian J. Cox, Frank Reimann, Patricia L. Brubaker, Alice E. Adriaenssens, Alexandre Martchenko, Everan Michalchyshyn, Jennifer A. Chalmers, Alessandro Doria, Emilia Mitova, Josyf C. Mychaleckyj, Fiona M. Gribble
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 31, Iss, Pp 124-137 (2020)
Molecular Metabolism, Vol 31, Iss, Pp 124-137 (2020)
Objectives The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted from intestinal L-cells upon nutrient intake. While recent evidence has shown that GLP-1 is released in a circadian manner in rats, whether this occurs in mice and if this pa
Publikováno v:
Endocrinology
Circadian rhythms are 24-hour biological rhythms within organisms that have developed over evolutionary time due to predefined environmental changes, mainly the light-dark cycle. Interestingly, metabolic tissues, which are largely responsible for est