Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Andrew D. Bates"'
Autor:
Alice L. B. Pyne, Agnes Noy, Kavit H. S. Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenall, Fiorella M. Cugliandolo, Joseph G. Beton, Clare E. M. Stevenson, Bart W. Hoogenboom, Andrew D. Bates, Anthony Maxwell, Sarah A. Harris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In cells, DNA is arranged into topologically-constrained (supercoiled) structures, but how this supercoiling affects the detailed double-helical structure of DNA remains unclear. Here authors use atomic force microscopy and atomistic molecular dynami
Externí odkaz:
https://doaj.org/article/728c1ae4dbb4491c9742de5d69efdcab
Autor:
Andrew D Bates, Anthony Maxwell
DNA as the genetic material is a topic of intense interest in the 21st century with the familiar and iconic Watson-Crick double helix having a vital importance for its function. However, there are further complexities beyond the double helix, includi
Autor:
Agnes Noy, Anthony Maxwell, Alice L. B. Pyne, Kavit Main, Michael M. Piperakis, Joseph G. Beton, Bart W. Hoogenboom, Clare E. M. Stevenson, Victor Velasco-Berrelleza, Fiorella M. Cugliandolo, Sarah A. Harris, Lesley A. Mitchenall, Andrew D. Bates
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the detailed double-helical structure of DNA, largely because of limitations in spatial resolu
Autor:
Clare E. M. Stevenson, Lesley A. Mitchenall, Alice L. B. Pyne, Kavit Main, Anthony Maxwell, Joseph G. Beton, Sarah A. Harris, Bart W. Hoogenboom, Agnes Noy, Victor Velasco-Berrelleza, Fiorella M. Cugliandolo, Michael M. Piperakis, Andrew D. Bates
In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the detailed double-helical structure of DNA, largely because of limitations in spatial resolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e630f42c1141cf1b86c1483853509e98
https://doi.org/10.1101/863423
https://doi.org/10.1101/863423
Autor:
Andrew D. Bates, Anthony Maxwell
Publikováno v:
Physics of Life Reviews. 18:144-146
Autor:
Maurycy Daroch, Andrew D. Bates, Catharine A. Houghton, Andrew J. Carnell, Mark C. Wilkinson, Jonathan K. Moore, Lesley A. Iwanejko
Publikováno v:
Enzyme and Microbial Technology. :1-7
Here we describe the identification, purification and characterisation of glycosylated yellow laccase proteins from the basidiomycete fungus Stropharia aeruginosa. Biochemical characterisation of two yellow laccases, Yel1p and Yel3p, show that they a
Autor:
Andrew D. Bates, Aneta Białkowska, Lesley A. Iwanejko, Marianna Turkiewicz, Mark C. Wilkinson, Tomasz Florczak, Maurycy Daroch
Publikováno v:
Enzyme and Microbial Technology. 53:18-24
A lipase, LipG7, has been purified from the Antarctic filamentous fungus Geomyces sp. P7 which was found to be cold-adapted and able to retain/regain its activity after heat denaturation. The LipG7 exhibits 100% residual activity following 1h incubat
Publikováno v:
Biochemical Society Transactions. 41:565-570
Small DNA circles can occur in Nature, for example as protein-constrained loops, and can be synthesized by a number of methods. Such small circles provide tractable systems for the study of the structure, thermodynamics and molecular dynamics of clos
Publikováno v:
Nucleic Acids Research
Topoisomerases (topos) maintain DNA topology and influence DNA transaction processes by catalysing relaxation, supercoiling and decatenation reactions. In the cellular milieu, division of labour between different topos ensures topological homeostasis
Autor:
Ian A. O'Neil, Richard Cosstick, Inder Bhamra, Patricia Compagnone-Post, Lesley A. Iwanejko, Andrew D. Bates
Publikováno v:
Nucleic Acids Research
8-Nitro-2′-deoxyguanosine (8-nitrodG) is a relatively unstable, mutagenic lesion of DNA that is increasingly believed to be associated with tissue inflammation. Due to the lability of the glycosidic bond, 8-nitrodG cannot be incorporated into oligo