Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Andrew D Yurochko"'
Autor:
Maciej T Nogalski, Gary C T Chan, Emily V Stevenson, Donna K Collins-McMillen, Andrew D Yurochko
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003463 (2013)
We have established that HCMV acts as a specific ligand engaging and activating cellular integrins on monocytes. As a result, integrin signaling via Src activation leads to the functional activation of paxillin required for efficient viral entry and
Externí odkaz:
https://doaj.org/article/e08ee6e133b24746a9af40f6a861e6db
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human cytomegalovirus (HCMV) is a significant cause of morbidity and mortality in the immunocompromised and developing fetuses. Infection has also been linked to chronic inflammatory diseases, cardiovascular disease, and the development of certain ca
Externí odkaz:
https://doaj.org/article/9df979cbdfb34d30944522c303243c3a
Autor:
Byeong-Jae Lee, Chan-Ki Min, Meaghan Hancock, Daniel N. Streblow, Patrizia Caposio, Felicia D. Goodrum, Andrew D. Yurochko
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Viruses have evolved diverse strategies to manipulate cellular signaling pathways in order to promote infection and/or persistence. Human cytomegalovirus (HCMV) possesses a number of unique properties that allow the virus to alter cellular events req
Externí odkaz:
https://doaj.org/article/5c4294f8eb494330a7d035bdf35bd0b7
Autor:
Lindsey B. Crawford, Patrizia Caposio, Craig Kreklywich, Andrew H. Pham, Meaghan H. Hancock, Taylor A. Jones, Patricia P. Smith, Andrew D. Yurochko, Jay A. Nelson, Daniel N. Streblow
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human cytomegalovirus (HCMV) infection of CD34+ hematopoietic progenitor cells (CD34+ HPCs) provides a critical reservoir of virus in stem cell transplant patients, and viral reactivation remains a significant cause of morbidity and mortalit
Externí odkaz:
https://doaj.org/article/2213cd7c92b0456f946b96b2a577e848
Autor:
Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected ce
Externí odkaz:
https://doaj.org/article/e112ec564a7b40c191ff06dc9080fbc1
Autor:
Andrew D. Yurochko
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Viruses have evolved many novel mechanisms to promote infection and to mitigate the host cell response to that infection. In the article by M. H. Hancock et al. (mBio 8:e00109-17, 2017, https://doi.org/10.1128/mBio.00109-17 ), the authors de
Externí odkaz:
https://doaj.org/article/e8a7e69c78b848978e80a3ac3187d5a5
Autor:
Bailey S. Mosher, Heather L. Fulkerson, Tori Boyle, Liudmila S. Chesnokova, Stephen J. Cieply, Andrew D. Yurochko
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) exhibits a complex host-pathogen interaction with peripheral blood monocytes. We have identified a unique, cell-type specific retrograde-like intracellular trafficking pattern that HCMV utilizes to gain access to the mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaf8071a3c4a096bfa874f478206657
https://doi.org/10.1128/jvi.00819-22
https://doi.org/10.1128/jvi.00819-22
Autor:
William M. Baldwin, Robert D. Dayton, Aaron W. Bivins, Rona S. Scott, Andrew D. Yurochko, John A. Vanchiere, Terry Davis, Connie L. Arnold, Jose.E.T. Asuncion, Mohammad A.N. Bhuiyan, Brandon Snead, William Daniel, Deborah G. Smith, Nicholas E. Goeders, Christopher G. Kevil, Jennifer Carroll, Kevin S. Murnane
Publikováno v:
Environmental Research. 222:115351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041f0ea94c1386a78effdf99db226c21
https://doi.org/10.1016/j.envres.2023.115351
https://doi.org/10.1016/j.envres.2023.115351
Autor:
Jung Heon Kim, Heather L Fulkerson, Gary C. Chan, Laura E Frazier, Liudmila S. Chesnokova, Jamil Mahmud, Andrew D. Yurochko
Publikováno v:
Proc Natl Acad Sci U S A
Previous analysis of postentry events revealed that human cytomegalovirus (HCMV) displays a unique, extended nuclear translocation pattern in monocytes. We determined that c-Src signaling through pentamer engagement of integrins is required upon HCMV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21de1b9abe923cd4dca183a551fe58ed
https://doi.org/10.1073/pnas.2003549117
https://doi.org/10.1073/pnas.2003549117
Autor:
Rachel M. Gerstein, Patrizia Caposio, Gary C. Chan, Jill M. Perreira, Ronghua ZhuGe, Timothy F. Kowalik, Paul Meraner, Andrew D. Yurochko, Abraham L. Brass, Xiaofei E, William M. McDougall, Aaron M. Aker, Ping Lu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Identifying cell-surface receptors required for viral infection is important for developing antiviral therapies and effective vaccines. Human cytomegalovirus (HCMV) infects epithelial cells during interhost transmission. The pentameric p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17eda7aeda16760e9d96fb80ab538609
https://doi.org/10.1073/pnas.1814850116
https://doi.org/10.1073/pnas.1814850116