Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Andrew D Yurochko"'
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human cytomegalovirus (HCMV) is a significant cause of morbidity and mortality in the immunocompromised and developing fetuses. Infection has also been linked to chronic inflammatory diseases, cardiovascular disease, and the development of certain ca
Externí odkaz:
https://doaj.org/article/9df979cbdfb34d30944522c303243c3a
Autor:
Byeong-Jae Lee, Chan-Ki Min, Meaghan Hancock, Daniel N. Streblow, Patrizia Caposio, Felicia D. Goodrum, Andrew D. Yurochko
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Viruses have evolved diverse strategies to manipulate cellular signaling pathways in order to promote infection and/or persistence. Human cytomegalovirus (HCMV) possesses a number of unique properties that allow the virus to alter cellular events req
Externí odkaz:
https://doaj.org/article/5c4294f8eb494330a7d035bdf35bd0b7
Autor:
Chan-Ki Min, Akhalesh K. Shakya, Byeong-Jae Lee, Daniel N. Streblow, Patrizia Caposio, Andrew D. Yurochko
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Viral dissemination is a key mechanism responsible for persistence and disease following human cytomegalovirus (HCMV) infection. Monocytes play a pivotal role in viral dissemination to organ tissue during primary infection and following reactivation
Externí odkaz:
https://doaj.org/article/f0f19a05541441f78a83141f40b1e6a3
Autor:
Lindsey B. Crawford, Patrizia Caposio, Craig Kreklywich, Andrew H. Pham, Meaghan H. Hancock, Taylor A. Jones, Patricia P. Smith, Andrew D. Yurochko, Jay A. Nelson, Daniel N. Streblow
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human cytomegalovirus (HCMV) infection of CD34+ hematopoietic progenitor cells (CD34+ HPCs) provides a critical reservoir of virus in stem cell transplant patients, and viral reactivation remains a significant cause of morbidity and mortalit
Externí odkaz:
https://doaj.org/article/2213cd7c92b0456f946b96b2a577e848
Autor:
Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Andrew D. Yurochko, Felicia D. Goodrum, Jay A. Nelson, Patrizia Caposio
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 525 (2020)
Human cytomegalovirus (HCMV) infection is a serious complication in hematopoietic stem cell transplant (HSCT) recipients due to virus-induced myelosuppression and impairment of stem cell engraftment. Despite the clear clinical link between myelosuppr
Externí odkaz:
https://doaj.org/article/fd04cf77fd6d44d2a57c0f8ec7654d01
Autor:
Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected ce
Externí odkaz:
https://doaj.org/article/e112ec564a7b40c191ff06dc9080fbc1
Autor:
Andrew D. Yurochko
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Viruses have evolved many novel mechanisms to promote infection and to mitigate the host cell response to that infection. In the article by M. H. Hancock et al. (mBio 8:e00109-17, 2017, https://doi.org/10.1128/mBio.00109-17 ), the authors de
Externí odkaz:
https://doaj.org/article/e8a7e69c78b848978e80a3ac3187d5a5
Autor:
Bailey S. Mosher, Heather L. Fulkerson, Tori Boyle, Liudmila S. Chesnokova, Stephen J. Cieply, Andrew D. Yurochko
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) exhibits a complex host-pathogen interaction with peripheral blood monocytes. We have identified a unique, cell-type specific retrograde-like intracellular trafficking pattern that HCMV utilizes to gain access to the mono
Autor:
Emily V. Stevenson, Donna Collins-McMillen, Jung Heon Kim, Stephen J. Cieply, Gretchen L. Bentz, Andrew D. Yurochko
Publikováno v:
Viruses, Vol 6, Iss 2, Pp 782-807 (2014)
The wide range of disease pathologies seen in multiple organ sites associated with human cytomegalovirus (HCMV) infection results from the systemic hematogenous dissemination of the virus, which is mediated predominately by infected monocytes. In add
Externí odkaz:
https://doaj.org/article/d06780e9e14a470386ea7ca4de64f54d
Autor:
William M. Baldwin, Robert D. Dayton, Aaron W. Bivins, Rona S. Scott, Andrew D. Yurochko, John A. Vanchiere, Terry Davis, Connie L. Arnold, Jose.E.T. Asuncion, Mohammad A.N. Bhuiyan, Brandon Snead, William Daniel, Deborah G. Smith, Nicholas E. Goeders, Christopher G. Kevil, Jennifer Carroll, Kevin S. Murnane
Publikováno v:
Environmental Research. 222:115351