Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Andrew D Watt"'
Autor:
Afsana Afroz, Bodrun Naher Siddiquea, Hasina Akhter Chowdhury, Timothy Nw Jackson, Andrew D Watt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012080 (2024)
BackgroundSnakebite envenoming represents a significant and often neglected public health challenge, particularly in rural communities across tropical and subtropical regions. An estimated 1.2-5.5 million people are envenomed by snakebites annually.
Externí odkaz:
https://doaj.org/article/9178eb46f2f74b18b601ba9550d496ee
Autor:
Afsana Afroz, Bodrun Naher Siddiquea, Aishwarya Narendra Shetty, Timothy N W Jackson, Andrew D Watt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 2, p e0011048 (2023)
BackgroundSnakebite envenoming is a serious and life-threatening medical condition that predominantly affects people living in rural communities across Africa, Asia, and Latin America. As our climate changes, there is a growing concern that negative
Externí odkaz:
https://doaj.org/article/1f82f243ff0a41079c6c825571372d12
Publikováno v:
Journal of Alzheimer's Disease
There is hope that the continuing efforts of researchers will yield a disease-modifying drug for Alzheimer’s disease. Such a drug is likely to be capable of halting, or significantly slowing, the underlying pathological processes driving cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7779d4f738b895fdbe25bbe9a6e38562
https://doi.org/10.3233/jad-180865
https://doi.org/10.3233/jad-180865
Publikováno v:
Journal of Alzheimer's Disease. 68:1321-1323
Rosen et al. thoughtfully extend the ethical discussion surrounding disease-modifying therapies in late-stage Alzheimer's disease (AD) to correctly emphasize that the perceived quality of life (QoL) of the individual living with the disease is a crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaa94900547706d4fde7756a6bc8231
https://doi.org/10.3233/jad-190033
https://doi.org/10.3233/jad-190033
Autor:
S.J. Hermans, Kevin J. Barnham, Tracy L. Nero, Andrew D Watt, Luke A. Miles, Gabriela A. N. Crespi, Nancy C. Hancock, Michael W. Parker
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd4a711ba9c9e0d40720785688e0013
https://doi.org/10.1016/j.jalz.2018.06.738
https://doi.org/10.1016/j.jalz.2018.06.738
Autor:
Alan Rembach, Christopher Fowler, Keyla Perez, Brett Trounson, Rebecca L. Rumble, Victor L. Villemagne, Noel G. Faux, Kevin J. Barnham, Kelly K. Pertile, Andrew D Watt, Paul O'Donnell, Colin L. Masters, Ching-Seng Ang
Publikováno v:
Journal of Alzheimer's Disease. 44:1131-1143
Biomarkers enabling the preclinical identification of Alzheimer's disease (AD) remain one of the major unmet challenges in the field. The blood cellular fractions offer a viable alternative to current cerebrospinal fluid and neuroimaging modalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b403d89e0f4ed36a0a358339fea5d561
https://doi.org/10.3233/jad-142286
https://doi.org/10.3233/jad-142286
Autor:
Victor L. Villemagne, Kevin J. Barnham, Adam P Gunn, Gabriela A. N. Crespi, Keyla Perez, Andrew D Watt, Russell A. Down, Catriona McLean, Luke A. Miles, Michael W. Parker, David B. Ascher
Publikováno v:
Acta Neuropathologica. 127:803-810
Reducing amyloid-β peptide (Aβ) burden at the pre-symptomatic stages of Alzheimer's disease (AD) is currently the advocated clinical strategy for treating this disease. The most developed method for targeting Aβ is the use of monoclonal antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057bbedda794ead791033d29ca97bb19
https://doi.org/10.1007/s00401-014-1290-2
https://doi.org/10.1007/s00401-014-1290-2
Autor:
Andrew D Watt, Kevin J. Barnham, Blaine R. Roberts, Alan Rembach, Colin L. Masters, Timothy M. Ryan, James D. Doecke, William Wilson
Publikováno v:
Biomarkers in Medicine. 7:641-662
Alzheimer’s disease (AD) is the most common cause of dementia in the elderly population and attempts to develop therapies have been unsuccessful because there is no means to target an effective therapeutic window. CNS biomarkers are insightful but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f97cdef103d96cabf969c70480896f
https://doi.org/10.2217/bmm.13.59
https://doi.org/10.2217/bmm.13.59
Autor:
Noel G. Faux, Irene Volitakis, Brett Trounson, Blaine R. Roberts, James D. Doecke, Kathryn A. Ellis, Andrew D Watt, David Ames, Kelly K. Pertile, Victor L. Villemagne, Colin L. Masters, Ashley I. Bush, Ralph N. Martins, Alan Rembach, Christopher Fowler, William Wilson, Rebecca L. Rumble, Christopher C. Rowe
Publikováno v:
Journal of Alzheimer's Disease. 34:171-182
BACKGROUND: Several studies have reported that peripheral levels of copper and ceruloplasmin (CP) can differentiate patients with Alzheimer's disease (AD) from non-AD cases. The aim of this study was to determine the diagnostic value of serum copper,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ed712929ed5de1f3c9dc0d15dab372
https://doi.org/10.3233/jad-121474
https://doi.org/10.3233/jad-121474
Autor:
Lin Wai Hung, Keyla Perez, Nicki A. Sherrat, Colin L. Masters, Victor L. Villemagne, Andrew D Watt, Alan Rembach, Timothy Johanssen, Kevin J. Barnham, Craig A. Hutton, Michelle T. Fodero-Tavoletti, Catriona McLean, Woan Mei Kok
Publikováno v:
Acta Neuropathologica. 125:549-564
The formation of low-order oligomers of β-amyloid (Aβ) within the brain is widely believed to be a central component of Alzheimer's disease (AD) pathogenesis. However, despite advances in high-throughput and high-resolution techniques such as xMAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af5b27efaf04c5231af113afd742c16
https://doi.org/10.1007/s00401-013-1083-z
https://doi.org/10.1007/s00401-013-1083-z