Zobrazeno 1 - 10
of 723
pro vyhledávání: '"Andrew D Smith"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/e52c9ea152604e49a8d02146cd20677c
Autor:
Kissa W. Mwamwitwa, Bugusu Nyamweru, Mohamed A. Iwodyah, Gerald Sambu, Goodluck G. Nyondo, Emili Yondu, Adam M. Fimbo, Vicky Manyanga, Wilber Sabiiti, Danstan H. Shewiyo, Morven C. Shearer, Andrew D. Smith, Eliangiringa A. Kaale
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The aim of this study was to develop and validate a High-Performance Thin Layer Chromatographic (HPTLC) method for simultaneous determination of ceftriaxone and ceftriaxone e-isomer in powder for injection formulation. Ceftriaxone sodium inj
Externí odkaz:
https://doaj.org/article/b3b890b36f6a4b52b75890d6d52ca79a
Autor:
Lori L O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M Hasso, Young-Jin Lee, Alan Fang, Albert D Kim, Jinjin Guo, Trudy M Hong, Kevin A Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D Smith, Anton Valouev, Andrew P McMahon
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007181 (2018)
Nephron progenitor number determines nephron endowment; a reduced nephron count is linked to the onset of kidney disease. Several transcriptional regulators including Six2, Wt1, Osr1, Sall1, Eya1, Pax2, and Hox11 paralogues are required for specifica
Externí odkaz:
https://doaj.org/article/435e97a2f642461e8fa6f0e4415c1cce
Autor:
M Joaquina Delás, Leah R Sabin, Egor Dolzhenko, Simon RV Knott, Ester Munera Maravilla, Benjamin T Jackson, Sophia A Wild, Tatjana Kovacevic, Eva Maria Stork, Meng Zhou, Nicolas Erard, Emily Lee, David R Kelley, Mareike Roth, Inês AM Barbosa, Johannes Zuber, John L Rinn, Andrew D Smith, Gregory J Hannon
Publikováno v:
eLife, Vol 6 (2017)
A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis a
Externí odkaz:
https://doaj.org/article/e9c2590fa9734ed099eb3c9e83222b6f
Autor:
Kissa W. Mwamwitwa PhD, Elias M. Bukundi Msc, Betty A. Maganda PhD, Castory Munishi MPhil, Adam M. Fimbo PhD, Deus Buma PhD, Eva P. Muro PhD, Wilber Sabiiti PhD, Danstan H. Shewiyo PhD, Morven C. Shearer PhD, Andrew D. Smith PhD, Eliangiringa A. Kaale PhD
Publikováno v:
Inquiry: The Journal of Health Care Organization, Provision, and Financing, Vol 61 (2024)
The use of chiral medicines (possessing center(s) of asymmetric carbon) may cause adverse drug reactions (ADRs). The safety assurance of these medicines is critical. We aimed to evaluate registered and commonly used anti-infective chiral medicines ci
Externí odkaz:
https://doaj.org/article/f57cb79dcf0f4d78828dc7a9ca4fbbb3
Autor:
Ralf Eggeling, André Gohr, Jens Keilwagen, Michaela Mohr, Stefan Posch, Andrew D Smith, Ivo Grosse
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85629 (2014)
The binding affinity of DNA-binding proteins such as transcription factors is mainly determined by the base composition of the corresponding binding site on the DNA strand. Most proteins do not bind only a single sequence, but rather a set of sequenc
Externí odkaz:
https://doaj.org/article/de9f98e2c7434908ae45c71a18e090e9
Autor:
Saleh Tamim, Dat T Vo, Philip J Uren, Mei Qiao, Eckart Bindewald, Wojciech K Kasprzak, Bruce A Shapiro, Helder I Nakaya, Suzanne C Burns, Patricia R Araujo, Ichiro Nakano, Agnes J Radek, Scott Kuersten, Andrew D Smith, Luiz O F Penalva
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85591 (2014)
miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma
Externí odkaz:
https://doaj.org/article/07dfca16fddd4fbc9d890bfd951dd082
Autor:
Joanne Preston, Andrew D Smith, Eleanor J Schofield, Alan V Chadwick, Mark A Jones, Joy E M Watts
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e84169 (2014)
The Tudor warship the Mary Rose has reached an important transition point in her conservation. The 19 year long process of spraying with polyethylene glycol (PEG) has been completed (April 29(th) 2013) and the hull is air drying under tightly control
Externí odkaz:
https://doaj.org/article/fbb3572e782345a4a9a49c99a67286a0
Autor:
Qiang Song, Benjamin Decato, Elizabeth E Hong, Meng Zhou, Fang Fang, Jianghan Qu, Tyler Garvin, Michael Kessler, Jun Zhou, Andrew D Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81148 (2013)
DNA methylation is implicated in a surprising diversity of regulatory, evolutionary processes and diseases in eukaryotes. The introduction of whole-genome bisulfite sequencing has enabled the study of DNA methylation at a single-base resolution, reve
Externí odkaz:
https://doaj.org/article/1962e1593e194a7e84cb8f31f867c408
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/56164988267a40edb89701b78f5da837