Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Andrew D Nelson"'
Autor:
Siavash Fazel Darbandi, Andrew D. Nelson, Emily Ling-lin Pai, Kevin J. Bender, John L. R. Rubenstein
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Tbr1 encodes a T-box transcription factor and is considered a high confidence autism spectrum disorder (ASD) gene. Tbr1 is expressed in the postmitotic excitatory neurons of the deep neocortical layers 5 and 6. Postnatally and neo
Externí odkaz:
https://doaj.org/article/84bffeb264cd437ea7a13c0b6e52968d
Autor:
J. Porter Hunt, Emily Long Zhao, Mehran Soltani, Madison Frei, J. Andrew D. Nelson, Bradley C. Bundy
Publikováno v:
Synthetic and Systems Biotechnology, Vol 4, Iss 4, Pp 220-224 (2019)
An “endotoxin-free” E. coli-based cell-free protein synthesis system has been reported to produce therapeutic proteins rapidly and on-demand. However, preparation of the most complex CFPS reagent – the cell extract – remains time-consuming an
Externí odkaz:
https://doaj.org/article/0ac47d24b4404df2bf8c2ed1b80c3cfe
Autor:
Dennis M Echevarria-Cooper, Nicole A Hawkins, Sunita N Misra, Alexandra M Huffman, Tyler Thaxton, Christopher H Thompson, Roy Ben-Shalom, Andrew D Nelson, Anna M Lipkin, Alfred L George Jr, Kevin J Bender, Jennifer A Kearney
Publikováno v:
Human Molecular Genetics. 31:2964-2988
Genetic variants in SCN2A, encoding the NaV1.2 voltage-gated sodium channel, are associated with a range of neurodevelopmental disorders with overlapping phenotypes. Some variants fit into a framework wherein gain-of-function missense variants that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ad66b61c945b641d39053bd5e0936c
https://doi.org/10.1093/hmg/ddac087
https://doi.org/10.1093/hmg/ddac087
Autor:
Sydney A. Smith, Caleb M. Lindgren, Landon E. Ebbert, Tyler J. Free, J. Andrew D. Nelson, Katelyn M. Simonson, J. Porter Hunt, Bradley C. Bundy
Publikováno v:
Biotechnology Progress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb14e73286458b95f72cc841b93a00e4
https://doi.org/10.1002/btpr.3332
https://doi.org/10.1002/btpr.3332
Autor:
Andrew D. Nelson, Paul M. Jenkins
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Neurons are highly specialized cells of the nervous system that receive, process and transmit electrical signals critical for normal brain function. Here, we review the intricate organization of axonal membrane domains that facilitate rapid action po
Externí odkaz:
https://doaj.org/article/053e84ad2cf041bc932dbe2f2cba0fb5
Autor:
Andrew D. Nelson, Amanda M. Catalfio, Julie M. Gupta, Lia Min, Rene N. Caballero-Floran, Kendall P. Dean, Carina C. Elvira, Kimberly D. Derderian, Henry Kyoung, Atehsa Sahagun, Stephan J. Sanders, Kevin J. Bender, Paul M. Jenkins
Dysfunction in sodium channels and their ankyrin scaffolding partners have both been implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD). In particular, the genes SCN2A, which encodes the sodium channel NaV1.2, and AN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da3ec1831db7357a03e80a8f144d952
https://doi.org/10.1101/2022.05.31.494205
https://doi.org/10.1101/2022.05.31.494205
Autor:
Serena Tamura, Andrew D. Nelson, Perry W.E. Spratt, Henry Kyoung, Xujia Zhou, Zizheng Li, Jingjing Zhao, Stephanie S. Holden, Atehsa Sahagun, Caroline M. Keeshen, Congyi Lu, Elizabeth C. Hamada, Roy Ben-Shalom, Jen Q. Pan, Jeanne T. Paz, Stephan J. Sanders, Navneet Matharu, Nadav Ahituv, Kevin J. Bender
The majority of autism spectrum disorder (ASD) risk genes are associated with ASD due to haploinsufficiency, where only one gene copy is functional. Here, using SCN2A haploinsufficiency, a major risk factor for ASD, we show that increasing the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d212615c2b4c849b63226b88633234
https://doi.org/10.1101/2022.03.30.486483
https://doi.org/10.1101/2022.03.30.486483
Autor:
Annie Dufficy, Andrew D. Nelson, Sebastian Fernando Torrealba, Marcus Vinícius Estigoni, Guilherme de Lima
Publikováno v:
Integrated Environmental Assessment and Management. 16:572-582
The debris flood created by the 5 November 2015 failure of the Fundão dam in Brazil injected a large amount of fine sediment in the Gualaxo do Norte River system. Although coarse and sand-sized sediment injections in rivers have been studied in rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407a590a63e5cf706a4b2c3df504d224
https://doi.org/10.1002/ieam.4293
https://doi.org/10.1002/ieam.4293
Publikováno v:
Case Reports in Pulmonology, Vol 2015 (2015)
We describe the development of rheumatoid factor-positive migratory polyarthritis in a 5-year-old male who had been administered bidaily oral mineral oil as a laxative since birth. Minor respiratory symptoms, radiographic and bronchoscopic findings w
Externí odkaz:
https://doaj.org/article/f8f63cf7362941a4aaa1987c6ff5ace8
Publikováno v:
The Science of the total environment. 826
Variation in sediment yield may reflect a signal of disturbances in the upstream landscape, modified by sediment routing. This study, conducted in a forested drainage basin in the inland Pacific Northwest, USA, sought to generate a better insight int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3288d383d98f8df044307f181decb8
https://pubmed.ncbi.nlm.nih.gov/35181366
https://pubmed.ncbi.nlm.nih.gov/35181366