Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

Autor: Martyn A. Sharpe, Andrew D. Livingston, Taylor L. Gist, Pardip Ghosh, Junyan Han, David S. Baskin

Publikováno v: EBioMedicine, Vol 2, Iss 9, Pp 1122-1132 (2015)

The last major advance in the treatment of glioblastoma multiforme (GBM) was the introduction of temozolomide in 1999. Treatment with temozolomide following surgical debulking extends survival rate compared to radiotherapy and debulking alone. Howeve

Externí odkaz: https://doaj.org/article/9a0a9c3e875642ee9b1dd58b1d72a711

Acute Onset of Guillain-Barré Syndrome After Elective Spinal Surgery

Autor: Ericka Simpson, Paul J. Holman, Andrew D. Livingston, Zain Boghani, Robert G. Grossman

Publikováno v: World Neurosurgery. 84:376-379

Background Guillain-Barre syndrome (GBS) is an acute peripheral neuropathy caused by an autoimmune response against myelin of peripheral nerves. GBS has been reported after surgery, in general, and after spinal surgery, in particular. In most cases,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ae8071a2fa48d41e0a55f11c7775c6
https://doi.org/10.1016/j.wneu.2015.03.036

Dissemination of Prostate Adenocarcinoma to the Skull Base Mimicking Giant Trigeminal Schwannoma: Anatomic Relevance of the Extradural Neural Axis Component

Autor: Yi Jonathan Zhang, James E. Rose, Yvonne Kew, Jaime Gasco, Andrew D. Livingston

Publikováno v: Skull Base. 19:425-430

We report an unusual case of a large metastatic lesion from prostate adenocarcinoma with its epicenter located in Meckel's cave. The patient presented with acute neurological deterioration due to pontomesencephalic, cranial nerve, and temporal lobe c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2455d5c117527d59d5f6d678eabd7237
https://doi.org/10.1055/s-0029-1224774

Sacral radiculopathy due to cement leakage from percutaneous sacroplasty, successfully treated with surgical decompression

Autor: Andrew D. Livingston, David A. Cech, Sean M. Barber

Publikováno v: Journal of neurosurgery. Spine. 18(5)

Percutaneous sacroplasty is a procedure adapted from vertebroplasty, which is designed to ameliorate the painful morbidity associated with sacral insufficiency fractures without the invasiveness of open surgery. Early estimates of efficacy, according

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39ae1bc16795b3ea17fc48d4487657e
https://pubmed.ncbi.nlm.nih.gov/23521686

GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

Autor: Paul Dickinson, Kevin A. Robertson, Marie Craigon, Thorsten Forster, Stuart L. Moodie, Garwin Sing, Muriel Mewissen, Andrew D Livingston, Alan J. Ross, Peter Ghazal, J. S. Beattie, Graeme R. Grimes

Publikováno v: Grimes, G R, Moodie, S, Beattie, J S, Craigon, M, Dickinson, P, Forster, T, Livingston, A D, Mewissen, M, Robertson, K A, Ross, A J, Sing, G & Ghazal, P 2005, ' GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults ', BMC Genomics, vol. 6, no. 178, pp. 1-8 . https://doi.org/10.1186/1471-2164-6-178
BMC Genomics
BMC Genomics, Vol 6, Iss 1, p 178 (2005)

Background Macrophages play an integral role in the host immune system, bridging innate and adaptive immunity. As such, they are finely attuned to extracellular and intracellular stimuli and respond by rapidly initiating multiple signalling cascades

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1047fa84d65952438694d385e94c854f
https://www.pure.ed.ac.uk/ws/files/1405408/Grimes_et_at_2005.pdf