Zobrazeno 1 - 10
of 449
pro vyhledávání: '"Andrew D, McCulloch"'
Autor:
Annabelle Fowler, Katherine R. Knaus, Stephanie Khuu, Ali Khalilimeybodi, Simon Schenk, Samuel R. Ward, Andrew C. Fry, Padmini Rangamani, Andrew D. McCulloch
Publikováno v:
Experimental Physiology, Vol 109, Iss 6, Pp 939-955 (2024)
Abstract Exercise‐induced muscle adaptations vary based on exercise modality and intensity. We constructed a signalling network model from 87 published studies of human or rodent skeletal muscle cell responses to endurance or resistance exercise in
Externí odkaz:
https://doaj.org/article/586603ec32d34a84bb57dc961d082bb0
Autor:
Sachin Govil, Brendan T. Crabb, Yu Deng, Laura Dal Toso, Esther Puyol-Antón, Kuberan Pushparajah, Sanjeet Hegde, James C. Perry, Jeffrey H. Omens, Albert Hsiao, Alistair A. Young, Andrew D. McCulloch
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 25, Iss 1, Pp 1-17 (2023)
Abstract Background Cardiac shape modeling is a useful computational tool that has provided quantitative insights into the mechanisms underlying dysfunction in heart disease. The manual input and time required to make cardiac shape models, however, l
Externí odkaz:
https://doaj.org/article/7253f2fe19814843b57f4da35e842e8e
Autor:
Sachin Govil, Charlène Mauger, Sanjeet Hegde, Christopher J. Occleshaw, Xiaoyang Yu, James C. Perry, Alistair A. Young, Jeffrey H. Omens, Andrew D. McCulloch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Current indications for pulmonary valve replacement (PVR) in repaired tetralogy of Fallot (rTOF) rely on cardiovascular magnetic resonance (CMR) image-based indices but are inconsistently applied, lead to mixed outcomes, and remain debated.
Externí odkaz:
https://doaj.org/article/5eef84314cdc4ee7bf4fd56c52eedb59
Autor:
Anna Mîra, Pablo Lamata, Kuberan Pushparajah, Georgina Abraham, Charlène A. Mauger, Andrew D. McCulloch, Jeffrey H. Omens, Malenka M. Bissell, Zach Blair, Tyler Huffaker, Animesh Tandon, Sandy Engelhardt, Sven Koehler, Thomas Pickardt, Philipp Beerbaum, Samir Sarikouch, Heiner Latus, Gerald Greil, Alistair A. Young, Tarique Hussain
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Maladaptive remodelling mechanisms occur in patients with repaired tetralogy of Fallot (rToF) resulting in a cycle of metabolic and structural changes. Biventricular shape analysis may indicate mechanisms associated with adverse e
Externí odkaz:
https://doaj.org/article/46946418b9d843c8970348b2e2cee889
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Mechanosignaling describes processes by which biomechanical stimuli are transduced into cellular responses. External biophysical forces can be transmitted via structural protein networks that span from the cellular membrane to the cytoskeleton and th
Externí odkaz:
https://doaj.org/article/a8c76fad22c34a39ab8411aede7882b8
Autor:
Charlène A. Mauger, Sachin Govil, Radomir Chabiniok, Kathleen Gilbert, Sanjeet Hegde, Tarique Hussain, Andrew D. McCulloch, Christopher J. Occleshaw, Jeffrey Omens, James C. Perry, Kuberan Pushparajah, Avan Suinesiaputra, Liang Zhong, Alistair A. Young
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Relationships between right ventricular (RV) and left ventricular (LV) shape and function may be useful in determining optimal timing for pulmonary valve replacement in patients with repaired tetralogy of Fallot (rTOF). However, t
Externí odkaz:
https://doaj.org/article/939fea1d2170486599fe9552534a2bd1
Right Ventricular Flow Vorticity Relationships With Biventricular Shape in Adult Tetralogy of Fallot
Autor:
Ayah Elsayed, Charlène A. Mauger, Edward Ferdian, Kathleen Gilbert, Miriam Scadeng, Christopher J. Occleshaw, Boris S. Lowe, Andrew D. McCulloch, Jeffrey H. Omens, Sachin Govil, Kuberan Pushparajah, Alistair A. Young
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Remodeling in adults with repaired tetralogy of Fallot (rToF) may occur due to chronic pulmonary regurgitation, but may also be related to altered flow patterns, including vortices. We aimed to correlate and quantify relationships between vorticity a
Externí odkaz:
https://doaj.org/article/c807bb0ed73b44c680bdcbe6ebf56952
Autor:
Hari K. Narayan, Ronghui Xu, Nickolas Forsch, Sachin Govil, David Iukuridze, Lanie Lindenfeld, Eric Adler, Sanjeet Hegde, Adriana Tremoulet, Bonnie Ky, Saro Armenian, Jeffrey Omens, Andrew D. McCulloch
Publikováno v:
Cardio-Oncology, Vol 6, Iss 1, Pp 1-9 (2020)
Abstract Background Adverse cardiac remodeling is an important precursor to anthracycline-related cardiac dysfunction, however conventional remodeling indices are limited. We sought to examine the utility of statistical atlas-derived measures of vent
Externí odkaz:
https://doaj.org/article/ef83fa9344c94b95af2e44beee2578c2
Autor:
Eric D. Carruth, Irvin Teh, Jurgen E. Schneider, Andrew D. McCulloch, Jeffrey H. Omens, Lawrence R. Frank
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Background Pressure overload left ventricular (LV) hypertrophy is characterized by increased cardiomyocyte width and ventricle wall thickness, however the regional variation of this remodeling is unclear. Cardiovascular magnetic resonance (C
Externí odkaz:
https://doaj.org/article/af3384477c1a49bab642ef5e82ffc6f2
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
A wide range of arrhythmogenic phenotypes have been associated with heterogeneous mechanical dyskinesis. Pro-arrhythmic effects are often associated with dysregulated intra-cellular calcium handling, especially via the development of intra- and inter
Externí odkaz:
https://doaj.org/article/92c44e5403204b9789c9db74eac53eee