Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Andrew D, Luster"'
Autor:
Laura Bricio-Moreno, Juliana Barreto de Albuquerque, Jake M. Neary, Thao Nguyen, Lucy F. Kuhn, YeePui Yeung, Kathryn M. Hastie, Sara Landeras-Bueno, Eduardo Olmedillas, Chitra Hariharan, Anusha Nathan, Matthew A. Getz, Alton C. Gayton, Ashok Khatri, Gaurav D. Gaiha, Erica Ollmann Saphire, Andrew D. Luster, James J. Moon
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Understanding adaptive immunity against SARS-CoV-2 is a major requisite for the development of effective vaccines and treatments for COVID-19. CD4+ T cells play an integral role in this process primarily by generating antiviral cytokines and providin
Externí odkaz:
https://doaj.org/article/c24e9f2a0035458781607e8fc3058230
Autor:
Hen Prizant, Nilesh Patil, Seble Negatu, Noor Bala, Alexander McGurk, Scott A. Leddon, Angela Hughson, Tristan D. McRae, Yu-Rong Gao, Alexandra M. Livingstone, Joanna R. Groom, Andrew D. Luster, Deborah J. Fowell
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109523- (2021)
Summary: Correct positioning of T cells within infected tissues is critical for T cell activation and pathogen control. Upon tissue entry, effector T cells must efficiently locate antigen-presenting cells (APC) for peripheral activation. We reveal th
Externí odkaz:
https://doaj.org/article/0a85c8030eb34cd78c988f80a522b72a
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: Generating robust CD4+ T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting a
Externí odkaz:
https://doaj.org/article/9420a957baf34ddb9e5d4ea8ab298466
Autor:
Alessandro Angelini, Yoshishige Miyabe, Daniel Newsted, Byron H. Kwan, Chie Miyabe, Ryan L. Kelly, Misha N. Jamy, Andrew D. Luster, K. Dane Wittrup
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
CXCR2 antagonism has been shown to be anti-arthritic, but anti-chemokine therapies usually fail in the clinic owing to redundancy in chemokine-receptor interactions. Here the authors develop single-chain antibodies with multiple chemokine specificiti
Externí odkaz:
https://doaj.org/article/c0b1123a348f40e095ceb7693a617ee1
Autor:
Björn Corleis, Allison N. Bucsan, Maud Deruaz, Vladimir D. Vrbanac, Antonella C. Lisanti-Park, Samantha J. Gates, Alice H. Linder, Jeffrey M. Paer, Gregory S. Olson, Brittany A. Bowman, Abigail E. Schiff, Benjamin D. Medoff, Andrew M. Tager, Andrew D. Luster, Shabaana A. Khader, Deepak Kaushal, Douglas S. Kwon
Publikováno v:
Cell Reports, Vol 26, Iss 6, Pp 1409-1418.e5 (2019)
Summary: Lung interstitial CD4+ T cells are critical for protection against pulmonary infections, but the fate of this population during HIV-1 infection is not well described. We studied CD4+ T cells in the setting of HIV-1 infection in human lung ti
Externí odkaz:
https://doaj.org/article/c3a8ebd845244172b1ccf580eea85e7f
Autor:
Jehan Alladina, Neal P. Smith, Tristan Kooistra, Kamil Slowikowski, Isabela J. Kernin, Jacques Deguine, Henry L. Keen, Kasidet Manakongtreecheep, Jessica Tantivit, Rod A. Rahimi, Susan L. Sheng, Nhan D. Nguyen, Alexis M. Haring, Francesca L. Giacona, Lida P. Hariri, Ramnik J. Xavier, Andrew D. Luster, Alexandra-Chloé Villani, Josalyn L. Cho, Benjamin D. Medoff
Publikováno v:
Science Immunology. 8
Asthma is a chronic disease most commonly associated with allergy and type 2 inflammation. However, the mechanisms that link airway inflammation to the structural changes that define asthma are incompletely understood. Using a human model of allergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac21e1ceafad0c752193c03305d44e3
https://doi.org/10.1126/sciimmunol.abq6352
https://doi.org/10.1126/sciimmunol.abq6352
Autor:
Albert Zlotnik, Osamu Yoshie, Mohib Uddin, Marcus Thelen, Alexander H. Sparre-Ulrich, Silvano Sozzani, Antal Rot, Mette M. Rosenkilde, Amanda E. I. Proudfoot, Christine A. Power, Joost J. Oppenheim, Hisayuki Nomiyama, Robert J. B. Nibbs, Philip M. Murphy, Georgios L. Moschovakis, Amy E. Monaghan, Kouji Matsushima, Alberto Mantovani, Andrew D. Luster, Massimo Locati, Richard Horuk, Rebecca Hills, Gerard J. Graham, Joshua M. Farber, Reinhold Förster, Christophe Combadiere, Israel F. Charo, Amanda M. Burkhardt, Adit Ben-Baruch, Francoise Bachelerie
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [438, 437, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdabff92dd3a87ec119470747102cddc
https://doi.org/10.2218/gtopdb/f14/2023.1
https://doi.org/10.2218/gtopdb/f14/2023.1
Autor:
Isabella C. Hirako, Marco A. Ataide, Lucas Faustino, Patricia A. Assis, Elizabeth W. Sorensen, Hisashi Ueta, Natalia M. Araújo, Gustavo B. Menezes, Andrew D. Luster, Ricardo T. Gazzinelli
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Cerebral malaria is an often fatal complication ofPlasmodium infection involving accumulation of inflammatory leukocytes in the central nervous system. Here the authors map the development and trafficking of CCR5+ monocyte-derived dendritic cells fro
Externí odkaz:
https://doaj.org/article/e5eb47b2e1724e06b7bcc6f82348fd32
Autor:
Lee Adam Wheeler, Radiana T. Trifonova, Vladimir Vrbanac, Natasha S. Barteneva, Xing Liu, Brooke Bollman, Lauren Onofrey, Sachin Mulik, Shahin Ranjbar, Andrew D. Luster, Andrew M. Tager, Judy Lieberman
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1715-1727 (2016)
Despite their antiviral effect, the in vivo effect of interferons on HIV transmission is difficult to predict, because interferons also activate and recruit HIV-susceptible cells to sites of infection. HIV does not normally induce type I interferons
Externí odkaz:
https://doaj.org/article/940201b95fe94b65a6d5c87d94abd150
Autor:
April M. Jorge, Taotao Lao, Rachel Kim, Samantha Licciardi, Joseph El Khoury, Andrew D. Luster, Terry K. Means, Zaida G. Ramirez-Ortiz
Publikováno v:
J Immunol
Deficiency in the clearance of cellular debris is a major pathogenic factor in the emergence of autoimmune diseases. We previously demonstrated that mice deficient for scavenger receptor class F member 1 (SCARF1) develop a lupus-like autoimmune disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073a8d89b632e720d9f187176749d663
https://doi.org/10.4049/jimmunol.2100532
https://doi.org/10.4049/jimmunol.2100532