Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Andrew D, Griffiths"'
Autor:
Sandeep Ameta, Simon Arsène, Sophie Foulon, Baptiste Saudemont, Bryce E. Clifton, Andrew D. Griffiths, Philippe Nghe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Autocatalytic networks may have started evolution during the origin of life. Here, the authors establish a landscape of thousands of RNA networks by barcoded sequencing and microfluidics, and derive relationships between topology and Darwinian proper
Externí odkaz:
https://doaj.org/article/6d823f6cb37a4853929c43211e561f99
Autor:
François Mallet, Léa Diouf, Boris Meunier, Magali Perret, Frédéric Reynier, Philippe Leissner, Laurence Quemeneur, Andrew D. Griffiths, Virginie Moucadel, Alexandre Pachot, Fabienne Venet, Guillaume Monneret, Alain Lepape, Thomas Rimmelé, Lionel K. Tan, Karen Brengel-Pesce, Julien Textoris
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionWe analysed blood DNAemia of TTV and four herpesviruses (CMV, EBV, HHV6, and HSV-1) in the REAnimation Low Immune Status Marker (REALISM) cohort of critically ill patients who had presented with either sepsis, burns, severe trauma, or maj
Externí odkaz:
https://doaj.org/article/82deb0a7f6ea4478b09c1d14639fd76e
Autor:
Maxime Bodinier, Estelle Peronnet, Karen Brengel-Pesce, Filippo Conti, Thomas Rimmelé, Julien Textoris, Christophe Vedrine, Laurence Quemeneur, Andrew D. Griffiths, Lionel K. Tan, Fabienne Venet, Delphine Maucort-Boulch, Guillaume Monneret, the REALISM study group
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The immune system plays a key role in sepsis onset and remains dysregulated over time in a heterogeneous manner. Here, we decipher the heterogeneity o
Externí odkaz:
https://doaj.org/article/2cd9c0d146304e6d83a767d4e12c26e6
Autor:
Sebastian Hutchinson, Sophie Foulon, Aline Crouzols, Roberta Menafra, Brice Rotureau, Andrew D Griffiths, Philippe Bastin
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009904 (2021)
The long and complex Trypanosoma brucei development in the tsetse fly vector culminates when parasites gain mammalian infectivity in the salivary glands. A key step in this process is the establishment of monoallelic variant surface glycoprotein (VSG
Externí odkaz:
https://doaj.org/article/7b767c10b42f4580b431be7a1bac6069
Autor:
Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, TR Thurston, T. R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg
Publikováno v:
Science. 378:186-192
Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with single-molecule sensitivity. Here, we demonstrate single-molecule protein sequencing using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3367086ac787e208c4c79a68cbb83f
https://doi.org/10.1126/science.abo7651
https://doi.org/10.1126/science.abo7651
Autor:
Thomas Moragues, Diana Arguijo, Thomas Beneyton, Cyrus Modavi, Karolis Simutis, Adam R. Abate, Jean-Christophe Baret, Andrew J. deMello, Douglas Densmore, Andrew D. Griffiths
Publikováno v:
Nature Reviews Methods Primers. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d72cae8021d05ba5c85bf78a2727a1ed
https://doi.org/10.1038/s43586-023-00212-3
https://doi.org/10.1038/s43586-023-00212-3
RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling
Autor:
Sandeep Ameta, Camille N Lambert, Alex Blokhuis, Cyrille Jeancolas, Thomas Alline, Andrew D. Griffiths, Sandeep Krishna, Mykhailo Vybornyi, Philippe Nghe, Yoshiya J. Matsubara
Publikováno v:
Chemical Communications, 57(61), 7517-7520. ROYAL SOC CHEMISTRY
Chemical Communications (Cambridge, England)
Chemical Communications (Cambridge, England)
We demonstrate that a recombinase ribozyme achieves multiple functions in the same reaction network: self-reproduction, iterative elongation and circularization of other RNAs, leading to synthesis of diverse products predicted by a kinetic model. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eefbf9689632270e6facb197771c13b
https://doi.org/10.1039/d1cc02290c
https://doi.org/10.1039/d1cc02290c
Autor:
Denis Cottinet, Florence Condamine, Nicolas Bremond, Andrew D Griffiths, Paul B Rainey, J Arjan G M de Visser, Jean Baudry, Jérôme Bibette
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152395 (2016)
Determining the phenotype and genotype of single cells is central to understand microbial evolution. DNA sequencing technologies allow the detection of mutants at high resolution, but similar approaches for phenotypic analyses are still lacking. We s
Externí odkaz:
https://doaj.org/article/6332a03f34ec4c6fa0ba5c08143c43d9
Autor:
Andrew D Griffiths, Andrew J Powers, James H Rizor, Jacob T Fagnani, Shelby Cooper, Rosalynn K. Nguyen, Nicholas J. Hellenthal, Michael P Damiani, Daphne Monie
Publikováno v:
The American Surgeon. 86:773-781
Background Increased prevalence of patients on anticoagulants and the advent of new therapies raise concern over how these patients fare if they sustain a traumatic injury. We investigated the role of prehospitalization anticoagulation therapy in tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ea912fd119956eaf5a25bd629d3483
https://doi.org/10.1177/0003134820934419
https://doi.org/10.1177/0003134820934419
Autor:
Andrew D. Griffiths, Alexei Godina, Guillaume Mottet, Gaël A. Millot, Bingqing Shen, Samantha N. Stewart, Vera Menrath, Sosthene Essono, Baptiste Saudemont, Clément Nizak, Annabelle Gérard, Antoine Sautel-Caillé, Scott McNamara, Matthieu Delince, Sami Ellouze, Jean Baudry, Marcel Reichen, Pablo Canales-Herrerias, Charina Ortega, Patrick England, Carlos Castrillon, Odile Richard-Le Goff, Colin Brenan, Klaus Eyer, Pascaline Mary, Luis Briseño-Roa, Allan Jensen, Pierre Bruhns, Raphael Clement Li-Ming Doineau, Adam Woolfe, Roshan Kumar, Bin Jia, Bruno Iannascoli, Yannick Pousse, Kevin Grosselin, Gregory Rose, Adeline Poitou
Publikováno v:
Nature Biotechnology
Nature Biotechnology, 2020, 38, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, Nature Publishing Group, 2020, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, 38
Nature Biotechnology, 2020, 38, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, Nature Publishing Group, 2020, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, 38
International audience; Mining the antibody repertoire of plasma cells and plasmablasts could enable the discovery of useful antibodies for therapeutic or research purposes1. We present a method for high-throughput, single-cell screening of IgG-secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbfb651784dad67e1736e002c8ce9cc
https://doi.org/10.1038/s41587-020-0466-7
https://doi.org/10.1038/s41587-020-0466-7