Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrew Craig Donohue"'
Autor:
Sarah M. Y. Ng, Andrew Craig Donohue, Adrian Sulistio, Cindy C. Shu, John F. Quinn, Stephen Lonsdale Birkett, Michael R. Whittaker, Thomas P. Davis, David Valade, Christopher B. Little, Anton Blencowe, Alison M. Bendele, Friederike M. Mansfeld, Asha M. D’Souza, Felisa Reyes-Ortega, Russell John Tait, Greg G. Qiao
The most common treatment for osteoarthritis is daily oral administration of a nonsteroidal anti-inflammatory drug such as diclofenac. This daily dosage regime is often associated with severe side effects. In this study, we explored the potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a30b61e9ea86a32c81bda06881c0240
https://hdl.handle.net/11541.2/138572
https://hdl.handle.net/11541.2/138572
Autor:
Laura Andrau, Margarita Kurek, R Marcel Kling, Andrew Craig Donohue, Harrison Sikanyika, David M. Shackleford, Andrew F. Wilks, John Thomas Feutrill, Tracy L. Nero, Emmanuelle Fantino, Herbert R. Treutlein, Michelle Farrugia, Ian D Phillips, Michelle Leanne Styles, David Gerard Bourke, Jun Zeng, Thao Kim Nu Nguyen, Christopher J. Burns, James T. Palmer, Max Joffe, Xianyong Bu, Stephen Su, Susan A. Charman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5887-5892
A series of phenylaminopyrimidines has been identified as inhibitors of Janus kinases (JAKs). Development of this initial series led to the potent JAK2/JAK1 inhibitor CYT387 (N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0ae62a5d282604aedf6d7be8aa9d41
https://doi.org/10.1016/j.bmcl.2009.08.071
https://doi.org/10.1016/j.bmcl.2009.08.071
Publikováno v:
Tetrahedron: Asymmetry. 12:657-667
Enantioselective hydrogenation of some α,β-unsaturated nitriles and their corresponding methyl esters bearing a phthalimidomethyl substituent at the α-carbon using Rh-DuPHOS catalysts afforded β-amino acid precursors with modest e.e.s of up to 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807790e53ec9e9ca53d39b1487bfb98f
https://doi.org/10.1016/s0957-4166(01)00097-0
https://doi.org/10.1016/s0957-4166(01)00097-0
Publikováno v:
ChemInform. 32
Enantioselective hydrogenation of some α,β-unsaturated nitriles and their corresponding methyl esters bearing a phthalimidomethyl substituent at the α-carbon using Rh-DuPHOS catalysts afforded β-amino acid precursors with modest e.e.s of up to 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef320b9d7834b4e7d10f3284e3d6b98b
https://doi.org/10.1002/chin.200131035
https://doi.org/10.1002/chin.200131035