Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrew Civitarese"'
Autor:
Natasha K. Tuano, Jonathan Beesley, Murray Manning, Wei Shi, Laura Perlaza-Jimenez, Luis F. Malaver-Ortega, Jacob M. Paynter, Debra Black, Andrew Civitarese, Karen McCue, Aaron Hatzipantelis, Kristine Hillman, Susanne Kaufmann, Haran Sivakumaran, Jose M. Polo, Roger R. Reddel, Vimla Band, Juliet D. French, Stacey L. Edwards, David R. Powell, Georgia Chenevix-Trench, Joseph Rosenbluh
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Background Genome-wide association studies (GWAS) have identified > 200 loci associated with breast cancer risk. The majority of candidate causal variants are in non-coding regions and likely modulate cancer risk by regulating gene expressio
Externí odkaz:
https://doaj.org/article/6fa5b74012424fbe8ef3072e8a09b991
Autor:
Christos Xiao, Mariska Miranda, Wei Shi, Jonathan Beesley, Jodi M. Saunus, Andrew Civitarese, Debra M. Black, Meagan Ruppert, Melrine Pereira, Susan Jackson, Zachary Teale, Dylan Carter-Cusack, Lauren Kalinowski, Jamie R. Kutasovic, Amy E. McCart Reed, Herlina Y. Handoko, XiaoQing Chen, Darrell Bessette, Kelli MacDonald, Sunil R. Lakhani, Georgia Chenevix-Trench, Kara Britt, Fares Al-Ejeh
BackgroundGenome-wide association studies have identified a breast cancer risk locus at 19q13.31. The candidate causal variants at this locus are located in the first exon ofKCNN4.KCNN4, which regulates membrane potential and Ca2+signaling, is a good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21c8cc28c52b9353dcff96e792037d73
https://doi.org/10.1101/2023.04.25.538345
https://doi.org/10.1101/2023.04.25.538345
Autor:
Stacey L. Edwards, Francesmary Modugno, Michael E. Carney, Jonathan Tyrer, Klaus Bauman, Jue-Sheng Ong, Tanja Pejovic, Rosalind Glasspool, Matthias Dürst, Bryan M. McCauley, Javier Benitez, Andreas du Bois, Ann-Marie Patch, Karen McCue, Florian Heitz, Diether Lambrechts, Paul D.P. Pharoah, Beth Y. Karlan, David G. Huntsman, Matthias W. Beckmann, Wei Shi, Penelope M. Webb, Michelle M.M. Woo, Kathryn L. Terry, Georgia Chenevix-Trench, Puya Gharahkhani, Melissa C. Larson, Kirsten B. Moysich, Estrid Høgdall, Sian Fereday, Julie M. Cunningham, Joellen M. Schildkraut, Andrew Civitarese, Jenny Lester, Peter A. Fasching, Ellen L. Goode, Stuart MacGregor, Jonathan Beesley, Allan Jensen, Michael Friedlander, Claus Høgdall, Stacey J. Winham, Yi Lu, Marc T. Goodman, Thilo Dörk, Dylan M. Glubb, Sharon E. Johnatty, Digna R. Velez Edwards, Tracy A. O'Mara, Melissa Moffitt, Taymaa May, Marjorie J. Riggan, Andrew Berchuck, Jacobus Pfisterer, Bo Gao, María Josefa Mosteiro García, Samantha Hinsley, Alicia Beeghly-Fadiel, Ignace Vergote, Michael C.J. Quinn, Sebastian M. Armasu, Anna deFazio, Line Bjørge, Daniel W. Cramer, Gabrielle Ene, Catherine J. Kennedy, Susanne K. Kjaer
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 30:1669-1680
Background: Many loci have been found to be associated with risk of epithelial ovarian cancer (EOC). However, although there is considerable variation in progression-free survival (PFS), no loci have been found to be associated with outcome at genome
CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci
Autor:
Joseph Rosenbluh, Natasha Tuano, Jonathan Beesley, Murray Manning, Wei Shi, Luis Malaver-Ortega, Jacob Paynter, Debra Black, Andrew Civitarese, Karen McCue, Aaron Hatzipantelis, Kristine Hillman, Susanne Kaufmann, Haran Sivakumaran, Jose Polo, Roger Reddel, Vimla Band, Juliet French, Stacey Edwards, David Powell, Georgia Chenevix-Trench
Genome-wide association studies (GWAS) have identified >200 loci associated with breast cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding regions and likely modulate cancer risk by regulating gene expression. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05b95125d449603d1d2e4477888a32e
https://doi.org/10.21203/rs.3.rs-1223972/v1
https://doi.org/10.21203/rs.3.rs-1223972/v1
CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci
Autor:
Wei Shi, Joseph Rosenbluh, Georgia Chenevix-Trench, Jonathan Beesley, Jacob M. Paynter, Juliet D. French, Roger R. Reddel, Vimla Band, Natasha K Tuano, Stacey L. Edwards, Andrew Civitarese, Debra Black, Aaron Hatzipantelis, Karen McCue, Luis F. Malaver-Ortega, Murray Manning, Jose M. Polo, Susanne Kaufmann, David R. Powell, Haran Sivakumaran, Kristine M. Hillman
SummaryGenome-wide association studies (GWAS) have identified >200 loci associated with breast cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding regions and are likely to modulate cancer risk by regulating gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13e2c6d144cc1f637a3193b5535d943
https://doi.org/10.1101/2021.09.07.459221
https://doi.org/10.1101/2021.09.07.459221
Autor:
Michael C J, Quinn, Karen, McCue, Wei, Shi, Sharon E, Johnatty, Jonathan, Beesley, Andrew, Civitarese, Tracy A, O'Mara, Dylan M, Glubb, Jonathan P, Tyrer, Sebastian M, Armasu, Jue-Sheng, Ong, Puya, Gharahkhani, Yi, Lu, Bo, Gao, Ann-Marie, Patch, Peter A, Fasching, Matthias W, Beckmann, Diether, Lambrechts, Ignace, Vergote, Digna R, Velez Edwards, Alicia, Beeghly-Fadiel, Javier, Benitez, Maria J, Garcia, Marc T, Goodman, Thilo, Dörk, Matthias, Dürst, Francesmary, Modugno, Kirsten, Moysich, Andreas, du Bois, Jacobus, Pfisterer, Klaus, Bauman, Beth Y, Karlan, Jenny, Lester, Julie M, Cunningham, Melissa C, Larson, Bryan M, McCauley, Susanne K, Kjaer, Allan, Jensen, Claus K, Hogdall, Estrid, Hogdall, Joellen M, Schildkraut, Marjorie J, Riggan, Andrew, Berchuck, Daniel W, Cramer, Kathryn L, Terry, Line, Bjorge, Penelope M, Webb, Michael, Friedlander, Tanja, Pejovic, Melissa, Moffitt, Rosalind, Glasspool, Taymaa, May, Gabrielle E V, Ene, David G, Huntsman, Michelle, Woo, Michael E, Carney, Samantha, Hinsley, Florian, Heitz, Sian, Fereday, Catherine J, Kennedy, Stacey L, Edwards, Stacey J, Winham, Anna, deFazio, Paul D P, Pharoah, Ellen L, Goode, Stuart, MacGregor, Georgia, Chenevix-Trench
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 30(9)
Many loci have been found to be associated with risk of epithelial ovarian cancer (EOC). However, although there is considerable variation in progression-free survival (PFS), no loci have been found to be associated with outcome at genome-wide levels