Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Andrew Chi Kin Law"'
Autor:
Way K.W. Lau, Andrew Chi Kin Law, Rui Feng, Sze-Wah Tam, Patrick Ka Kit Yeung, Sookja K. Chung
Publikováno v:
J Biol Chem
Endothelin-1 (ET-1) is a neuroactive peptide produced by neurons, reactive astrocytes, and endothelial cells in the brain. Elevated levels of ET-1 have been detected in the post-mortem brains of individuals with Alzheimer's disease (AD). We have prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29ee6cefb07c8d6129072abc9d60edf
https://doi.org/10.1074/jbc.ra118.005155
https://doi.org/10.1074/jbc.ra118.005155
Publikováno v:
Geriatrics & Gerontology International. 15:96-103
Aim The objective of the present study was to investigate the reliability and the validity of the Cantonese Chinese Montreal Cognitive Assessment (MoCA) as a brief screening tool of amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7af020fef8f40b614a1ea03b47437b6
https://doi.org/10.1111/ggi.12237
https://doi.org/10.1111/ggi.12237
Publikováno v:
Molecular Psychiatry. 19:159-167
Alzheimer's disease (AD) and vascular dementia are the major causes of cognitive disorders worldwide. They are characterized by cognitive impairments along with neuropsychiatric symptoms, and that their pathogeneses show overlapping multifactorial me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51a95db49ceb2f0a05a7be8cc334991
https://doi.org/10.1038/mp.2013.171
https://doi.org/10.1038/mp.2013.171
Publikováno v:
Ageing Research Reviews. 12:67-75
Depression is one of the most common psychiatric disorders with inadequately understood disease mechanisms. It has long been considered that dendritic regression and decrease in the number of dendritic spines are involved in depression. Dendrites mad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1752873f947b84ee1a87b3ac06d9d1ab
https://doi.org/10.1016/j.arr.2012.08.004
https://doi.org/10.1016/j.arr.2012.08.004
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3722aca2ae42510ed05e1e829626f6f1
https://doi.org/10.1016/j.jalz.2016.06.1274
https://doi.org/10.1016/j.jalz.2016.06.1274
Publikováno v:
Progress in Neurobiology. 91:362-375
Alzheimer's disease (AD) is the leading neurodegenerative cause of dementia in the elderly. Thus far, there is no curative treatment for this devastating condition, thereby creating significant social and medical burdens. AD is characterized by progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce19c4478c79b60b84ef26f52083f5c4
https://doi.org/10.1016/j.pneurobio.2010.04.005
https://doi.org/10.1016/j.pneurobio.2010.04.005
Publikováno v:
Neurobiology of Aging. 24:187-190
Impairments in cognitive performance have been observed in aged apolipoprotein E (apoE)-deficient mice, and apoE epsilon 4 allele is a risk factor in Alzheimer's disease (AD). The absence of apoE correlates with diminished antioxidative capacity in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5797f31772d1b15810b10a64a0affb4
https://doi.org/10.1016/s0197-4580(02)00068-4
https://doi.org/10.1016/s0197-4580(02)00068-4
Autor:
Andrew Chi Kin Law, Jerry Wing Fai Yeung, Jenny S.W. Lee, Corine Sau Man Wong, James Ka-Hay Luk, Wai Chi Chan, Linda C. W. Lam, Ka Fai Chung
Publikováno v:
Journal of the American Medical Directors Association. 16(2)
Objective Numerous studies have reported the prevention of falls through exercise among cognitively healthy older people. This study aimed to determine whether the current evidence supports that physical exercise is also efficacious in preventing fal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bacc0e5679eceefe5397504e02acb42c
https://pubmed.ncbi.nlm.nih.gov/25304179
https://pubmed.ncbi.nlm.nih.gov/25304179
Publikováno v:
British Journal of Pharmacology. 133:1114-1124
Beta amyloid (Aβ) is implicated in Alzheimer's disease (AD). Aβ1–42 (5, 10, or 20 μM) was able to increase NO release and decrease cellular viability in primary rat cortical mixed cultures. L-NOARG and SMTC (both at 10 or 100 μM) – type I NOS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfea65d28d32b9d246a12dcfa943f28
https://doi.org/10.1038/sj.bjp.0704179
https://doi.org/10.1038/sj.bjp.0704179
Publikováno v:
Neuroscience. 100:769-775
Neuronal nitric oxide synthase and haem oxygenase-2 are postulated to be important enzymes involved in neuronal transmission and modulation of free radical levels in neurons. Hippocampal and cortical neuronal nitric oxide synthase and haem oxygenase-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d839d9c37dea071bfb4fb3dfcad00576
https://doi.org/10.1016/s0306-4522(00)00316-x
https://doi.org/10.1016/s0306-4522(00)00316-x