Zobrazeno 1 - 10
of 773
pro vyhledávání: '"Andrew Chan"'
Autor:
Sneha Vishwanath, George William Carnell, Martina Billmeier, Luis Ohlendorf, Patrick Neckermann, Benedikt Asbach, Charlotte George, Maria Suau Sans, Andrew Chan, Joey Olivier, Angalee Nadesalingam, Sebastian Einhauser, Nigel Temperton, Diego Cantoni, Joe Grove, Ingo Jordan, Volker Sandig, Paul Tonks, Johannes Geiger, Christian Dohmen, Verena Mummert, Anne Rosalind Samuel, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Updates of SARS-CoV-2 vaccines are required to generate immunity in the population against constantly evolving SARS-CoV-2 variants of concerns (VOCs). Here we describe three novel in-silico designed spike-based antigens capable of inducing n
Externí odkaz:
https://doaj.org/article/82ef274560d34dc98c35687c198efcf5
Autor:
Madeleine Wiebe, Marnie Mackay, Ragur Krishnan, Julie Tian, Jakob Larsson, Setayesh Modanloo, Christiane Job McIntosh, Melissa Sztym, Gail Elton-Smith, Alyssa Rose, Chester Ho, Andrew Greenshaw, Bo Cao, Andrew Chan, Jake Hayward
Publikováno v:
PLOS Digital Health, Vol 3, Iss 8, p e0000571 (2024)
IntroductionCommon, consumer-grade biosensors mounted on fitness trackers and smartwatches can measure an array of biometrics that have potential utility in post-discharge medical monitoring, especially in remote/rural communities. The feasibility ch
Externí odkaz:
https://doaj.org/article/2ed7fe21c3544d61a51503a50d675401
Autor:
Matthias Schwab, Andrew Chan, Anna-Katharina Eser, Boris Kallmann, Dieter Pöhlau, Joachim Richter, Torsten B. Wagner, Christoph Grothe
Publikováno v:
Neurology and Therapy, Vol 13, Iss 3, Pp 641-653 (2024)
Abstract Introduction Treatment adherence is a critical success factor in the disease-modifying therapy (DMT) of multiple sclerosis (MS). The REBISTART study prospectively evaluated adherence in patients using components of a patient support program
Externí odkaz:
https://doaj.org/article/37e20567ddba4394b0fa4dbb255d5e11
Autor:
Michael Graber, Alice Panchaud, Helene Legardeur, Tobias Derfuss, Christoph Friedli, Claudio Gobbi, Chiara Zecca, Cristina Granziera, Ilijas Jelcic, Helly Noemi Hammer, Sandra Bigi, Lara Diem, Nicole Kamber, Veronika Kana, Jens Kuhle, Stefanie Müller, Anke Salmen, Robert Hoepner, Philipp Do Canto, Marie Théaudin, Daniel Surbek, Caroline Pot, Andrew Chan
Publikováno v:
Clinical and Translational Neuroscience, Vol 8, Iss 3, p 26 (2024)
A large number of disease-modifying immunotherapies are available for the treatment of people with multiple sclerosis. Many disease-modifying immunotherapies show scarce or no safety data in pregnancy and breastfeeding and are labeled as being contra
Externí odkaz:
https://doaj.org/article/86372ba7025c406cb56b08a023c68ebc
Autor:
Martina Greselin, Po-Jui Lu, Lester Melie-Garcia, Mario Ocampo-Pineda, Riccardo Galbusera, Alessandro Cagol, Matthias Weigel, Nina de Oliveira Siebenborn, Esther Ruberte, Pascal Benkert, Stefanie Müller, Sebastian Finkener, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Claire Bridel, Chiara Zecca, Tobias Derfuss, Johanna M. Lieb, Michael Diepers, Franca Wagner, Maria I. Vargas, Renaud Du Pasquier, Patrice H. Lalive, Emanuele Pravatà, Johannes Weber, Claudio Gobbi, David Leppert, Olaf Chan-Hi Kim, Philippe C. Cattin, Robert Hoepner, Patrick Roth, Ludwig Kappos, Jens Kuhle, Cristina Granziera
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 858 (2024)
The detection of contrast-enhancing lesions (CELs) is fundamental for the diagnosis and monitoring of patients with multiple sclerosis (MS). This task is time-consuming and suffers from high intra- and inter-rater variability in clinical practice. Ho
Externí odkaz:
https://doaj.org/article/753b7b7b06c042a89d9dbeabe7219d4d
Autor:
Christoph Friedli, Nik Krajnc, Helly N. Hammer, Stefanie Marti, Tobias Zrzavy, Maria E. Evangelopoulos, Ioanna Kapsali, Paulus Rommer, Thomas Berger, Andrew Chan, Gabriel Bsteh, Robert Hoepner
Publikováno v:
Journal of Central Nervous System Disease, Vol 16 (2024)
Introduction Patients with Multiple Sclerosis (pwMS) treated with anti-CD20 (cluster of differentiation) monoclonal antibodies (mAbs) such as ocrelizumab (OCR) and ofatumumab (OFA) show a reduction mainly of B-lymphocytes, but also other lymphocyte s
Externí odkaz:
https://doaj.org/article/f71d643750d84c1694bf98728b6a6655
Autor:
Pauline Thränhardt, Admirim Veselaj, Christoph Friedli, Franca Wagner, Stefanie Marti, Lara Diem, Helly Hammer, Piotr Radojewski, Roland Wiest, Andrew Chan, Robert Hoepner, Anke Salmen
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Reporting of sex-specific analyses in multiple sclerosis (MS) is sparse. Disability accrual results from relapses (relapse-associated worsening) and independent thereof (progression independent of relapses). Objectives: A population of MS
Externí odkaz:
https://doaj.org/article/a108a207b1be44cd83470a9499408994
Autor:
Vincent Pernet, Sandrine Joly, Sebastian Spiegel, Ivo Meli, Sherif Idriss, Frank Maigler, Julius Baya Mdzomba, Anna K. Roenneke, Alessandra Franceschini, Ludovico Silvestri, Francesco S. Pavone, Martino Calamai, Katharina Schindowski, Andrew Chan
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Systemic administration of Nogo-A-neutralizing antibody ameliorates experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. However, the blood-brain barrier (BBB) is a major obstacle limiting the passage of sy
Externí odkaz:
https://doaj.org/article/d00b63c25f75423b80156f4f14bad991
Publikováno v:
Sensors, Vol 24, Iss 14, p 4706 (2024)
As Canada’s population of older adults rises, the need for aging-in-place solutions is growing due to the declining quality of long-term-care homes and long wait times. While the current standards include questionnaire-based assessments for monitor
Externí odkaz:
https://doaj.org/article/12fca8ca4899480bbcfe8420f0ca9bfa
Autor:
Stephen L. Hauser, Ludwig Kappos, Amit Bar-Or, Heinz Wiendl, David Paling, Mitzi Williams, Ralf Gold, Andrew Chan, Ron Milo, Ayan Das Gupta, Goeril Karlsson, Roseanne Sullivan, Gordon Graham, Martin Merschhemke, Dieter A. Häring, Patrick Vermersch
Publikováno v:
Neurology and Therapy, Vol 12, Iss 5, Pp 1491-1515 (2023)
Abstract The importance of B cells in multiple sclerosis (MS) has been demonstrated through the advent of B-cell-depleting anti-CD20 antibody therapies. Ofatumumab is the first fully human anti-CD20 monoclonal antibody (mAb) developed and tested for
Externí odkaz:
https://doaj.org/article/eebd67c7598744dda6a94266f7a71dd5