Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Andrew Carroll"'
Autor:
Alexey Kolesnikov, Daniel Cook, Maria Nattestad, Lucas Brambrink, Brandy McNulty, John Gorzynski, Sneha Goenka, Euan A. Ashley, Miten Jain, Karen H. Miga, Benedict Paten, Pi-Chuan Chang, Andrew Carroll, Kishwar Shafin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Long-read sequencing technology has enabled variant detection in difficult-to-map regions of the genome and enabled rapid genetic diagnosis in clinical settings. Rapidly evolving third-generation sequencing platforms like Pacific Biosciences
Externí odkaz:
https://doaj.org/article/9736ff93823742a28239875aa6195f95
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTMany people experience traumatic or negative events, but few develop mental health issues as a result. This study investigated whether newborn DNA methylation (DNAm) previously associated with maternal childhood physical abuse by her father a
Externí odkaz:
https://doaj.org/article/cf9861d483fb4242835e4e772501d3da
P582: CSMD1 intragenic exonic deletions strengthen the association with neurodevelopmental disorders
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101488- (2024)
Externí odkaz:
https://doaj.org/article/71dca5844e9c4e609b9740dac766105a
Autor:
Min Gao, Yunjia Chen, Pongtawat Lertwilaiwittaya, Anna Hurst, Ali Al-Beshri, Andrew Carroll, Fady Mikhail
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101640- (2024)
Externí odkaz:
https://doaj.org/article/2520512b6e094ae4978e0ffaa31cad73
Autor:
Nae-Chyun Chen, Alexey Kolesnikov, Sidharth Goel, Taedong Yun, Pi-Chuan Chang, Andrew Carroll
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Large-scale population variant data is often used to filter and aid interpretation of variant calls in a single sample. These approaches do not incorporate population information directly into the process of variant calling, and are often li
Externí odkaz:
https://doaj.org/article/de20f720f9fe4afaaf0a8c86095f5110
Autor:
Keyur Talsania, Tsai-wei Shen, Xiongfong Chen, Erich Jaeger, Zhipan Li, Zhong Chen, Wanqiu Chen, Bao Tran, Rebecca Kusko, Limin Wang, Andy Wing Chun Pang, Zhaowei Yang, Sulbha Choudhari, Michael Colgan, Li Tai Fang, Andrew Carroll, Jyoti Shetty, Yuliya Kriga, Oksana German, Tatyana Smirnova, Tiantain Liu, Jing Li, Ben Kellman, Karl Hong, Alex R. Hastie, Aparna Natarajan, Ali Moshrefi, Anastasiya Granat, Tiffany Truong, Robin Bombardi, Veronnica Mankinen, Daoud Meerzaman, Christopher E. Mason, Jack Collins, Eric Stahlberg, Chunlin Xiao, Charles Wang, Wenming Xiao, Yongmei Zhao
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-33 (2022)
Abstract Background The cancer genome is commonly altered with thousands of structural rearrangements including insertions, deletions, translocation, inversions, duplications, and copy number variations. Thus, structural variant (SV) characterization
Externí odkaz:
https://doaj.org/article/3cca47d9f72844a39a3e5ac2ef139231
Autor:
Rachel Przeslawski, Neville Barrett, Andrew Carroll, Scott Foster, Brooke Gibbons, Alan Jordan, Jacquomo Monk, Tim Langlois, Ana Lara-Lopez, Jay Pearlman, Kim Picard, Joni Pini-Fitzsimmons, Paul van Ruth, Joel Williams
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Since 2012, there has been a surge in the numbers of marine science publications that use the term ‘best practice’, yet the term is not often defined, nor is the process behind the best practice development described. Importantly a ‘best practi
Externí odkaz:
https://doaj.org/article/f2bbb90d6d91409f9f06d96871c5316e
Autor:
Zachary R. McCaw, Thomas Colthurst, Taedong Yun, Nicholas A. Furlotte, Andrew Carroll, Babak Alipanahi, Cory Y. McLean, Farhad Hormozdiari
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
GWAS often assume a linear phenotype-covariate relationship which may not hold in practice. Here the authors present DeepNull, in which they apply deep learning to identify and adjust for complex non-linear relationships, improving phenotypic predict
Externí odkaz:
https://doaj.org/article/f951999ae2b6444297e7d38d051566d6
Autor:
Yunjia Chen, Ender Karaca, Nathaniel Robin, Dana Goodloe, Ali Al-Beshri, S. Joy Dean, Anna Hurst, Andrew Carroll, Fady Mikhail
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100487- (2023)
Externí odkaz:
https://doaj.org/article/04d79fbf72d44419b154ce328890d0a9
Autor:
Michael M. Khayat, Sayed Mohammad Ebrahim Sahraeian, Samantha Zarate, Andrew Carroll, Huixiao Hong, Bohu Pan, Leming Shi, Richard A. Gibbs, Marghoob Mohiyuddin, Yuanting Zheng, Fritz J. Sedlazeck
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Genomic structural variations (SV) are important determinants of genotypic and phenotypic changes in many organisms. However, the detection of SV from next-generation sequencing data remains challenging. Results In this study, DNA
Externí odkaz:
https://doaj.org/article/0f705634bb9d4e6ebe2949ac7601e5f7