Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew C. S. Saphire"'
Autor:
Philippe Gallay, Hsiu-Cheng Hung, Zhe Zhang, Andrew C. S. Saphire, Xiaocong Yu, Bernadette Van der Schueren, Michael Bobardt, Guido David
Publikováno v:
Immunity. 18:27-39
This study demonstrates that syndecan functions as an in trans HIV receptor. We show that syndecan, when expressed in nonpermissive cells, becomes the major mediator for HIV adsorption. This adsorption is mediated by the binding of gp120 to the hepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c26f556b6b3467b020558fff9cdc8d3
https://doi.org/10.1016/s1074-7613(02)00504-6
https://doi.org/10.1016/s1074-7613(02)00504-6
Publikováno v:
Journal of Virology. 75:9187-9200
To date, the human immunodeficiency virus type 1 (HIV-1) receptor complex known to be essential for virus entry consists of CD4 molecules expressed on T cells, macrophages, dendritic cells, and microglia and a member of the seven-transmembrane chemok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41feef68a7101790b3dcac6ec57832ba
https://doi.org/10.1128/jvi.75.19.9187-9200.2001
https://doi.org/10.1128/jvi.75.19.9187-9200.2001
Publikováno v:
The EMBO Journal. 18:6771-6785
The present study proposes a novel mode of action for cyclophilin A (CypA) in the HIV-1 life cycle. We demonstrate that CypA-deficient viruses do not replicate because they fail to attach to target cells. We show that CypA is exposed at the viral mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e88cbdcc26a7960f0a130294ea0403
https://doi.org/10.1093/emboj/18.23.6771
https://doi.org/10.1093/emboj/18.23.6771
Autor:
Andrew C. S. Saphire, D. A. Byrd, Larry Gerace, Tinglu Guan, U. Aebi, Nelly Panté, Konstantin N. Konstantinov, C. S. Cooper, Deborah J. Sweet, P. J. Mitchell
Publikováno v:
The Journal of Cell Biology
From a panel of monoclonal antibodies raised against fractions of rat liver nuclear envelopes (NEs), we have identified an antibody, RL30, which reacts with novel nuclear pore complex (NPC) antigens that are not O-glycosylated. By immunofluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d6d3c9b967c25cd389fc53e0731b29
http://europepmc.org/articles/PMC2120283
http://europepmc.org/articles/PMC2120283
Autor:
Andrew C. S. Saphire, Souad Naji, Géza Ambrus, Paul Vesely, Peter Cimermancic, Michael D. Huber, Jason R. Reyes, Nevan J. Krogan, Jeffrey R. Johnson, John R. Yates, Larry Gerace, Rebecca Filbrandt
Publikováno v:
Molecularcellular proteomics : MCP. 11(4)
The HIV-1 Rev protein plays a key role in the late phase of virus replication. It binds to the Rev Response Element found in underspliced HIV mRNAs, and drives their nuclear export by the CRM1 receptor pathway. Moreover, mounting evidence suggests th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddec47426a0d7263e774877d9a0dd4f0
https://pubmed.ncbi.nlm.nih.gov/22174317
https://pubmed.ncbi.nlm.nih.gov/22174317
Publikováno v:
Journal of proteome research. 5(3)
A major challenge to studying virus-incorporated host proteins is the fact that they are not encoded by the viral genome. We used Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) on whole virions to obtain a snapshot of the HIV-1 proteome. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dc5e880afa09139d2697ee7b3ba3a0
https://pubmed.ncbi.nlm.nih.gov/16512667
https://pubmed.ncbi.nlm.nih.gov/16512667
Publikováno v:
Journal of virology. 76(9)
Cyclophilin A (CypA) is necessary for effective human immunodeficiency virus type 1 (HIV-1) replication. However, the functions of CypA and the precise steps at which CypA acts in the HIV-1 life cycle remain to be determined. By using a methodology t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7757a5feec54ad7507171df9edc42405
https://pubmed.ncbi.nlm.nih.gov/11932436
https://pubmed.ncbi.nlm.nih.gov/11932436
Publikováno v:
The Journal of biological chemistry. 275(6)
Adenovirus, a respiratory virus with a double-stranded DNA genome, replicates in the nuclei of mammalian cells. We have developed a cytosol-dependent in vitro assay utilizing adenovirus nucleocapsids to examine the requirements for adenovirus docking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a56efe48eeeabfa6b74e1d407140048
https://pubmed.ncbi.nlm.nih.gov/10660598
https://pubmed.ncbi.nlm.nih.gov/10660598
Publikováno v:
The Journal of biological chemistry. 273(45)
The information that targets a protein to the nucleus often consists of a short cluster of basic amino acids called a nuclear localization sequence (NLS). Since a wide range of sequences rich in basic amino acid residues function as NLSs, we postulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae4c7ec6e4f0ca4af33c8e0614edd74
https://pubmed.ncbi.nlm.nih.gov/9792690
https://pubmed.ncbi.nlm.nih.gov/9792690
Publikováno v:
Journal of Proteome Research. 5:1279-1279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0232adfb70c840fb42553a979935c5ce
https://doi.org/10.1021/pr068001z
https://doi.org/10.1021/pr068001z