Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Andrew C. Rankin"'
Publikováno v:
Clinical Hemorheology and Microcirculation. 5:281-289
Publikováno v:
Postgraduate Medical Journal. 91:379-383
Background Doctors are taught to auscultate with the stethoscope applied to the skin, but in practice may be seen applying the stethoscope to the gown. Objectives To determine how often doctors auscultate heart and breath sounds through patients’ g
Publikováno v:
QJM. 107:895-902
Background: A recording of ≥30 s is required for diagnosis of paroxysmal atrial fibrillation (AF) when using ambulatory electrocardiography (ECG) monitoring. It is unclear if shorter runs of atrial arrhythmia are relevant with regard to stroke risk
Autor:
Arun V. Holden, Antony J. Workman, Irina V. Biktasheva, Sanjay Kharche, Henggui Zhang, Michael A. Colman, Tomas Stary, Andrew C. Rankin
Publikováno v:
EP Europace. 16:1524-1533
Aims Atrial anti-arrhythmic effects of β-adrenoceptor antagonists (β-blockers) may involve both a suppression of pro-arrhythmic effects of catecholamines, and an adaptational electrophysiological response to chronic β-blocker use; so-called ‘pha
Publikováno v:
The Journal of Physiology. 590:4289-4305
Human atrial transient outward K(+) current (I(TO)) is decreased in a variety of cardiac pathologies, but how I(TO) reduction alters action potentials (APs) and arrhythmia mechanisms is poorly understood, owing to non-selectivity of I(TO) blockers. T
Autor:
Susan Currie, Kathleen A. Kane, Andrew C. Rankin, Julie Russell, Antony J. Workman, John Dempster, Gillian E. Marshall, Pardeep S. Jhund, James O. Tellez, Mark R. Boyett
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 463:537-548
Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K(+) currents. The aim of
Publikováno v:
Pharmacology & Therapeutics. 131:221-241
Atrial fibrillation (AF) is a disorder of the rhythm of electrical activation of the cardiac atria. It is the most common cardiac arrhythmia, has multiple aetiologies, and increases the risk of death from stroke. Pharmacological therapy is the mainst
Autor:
Antony J. Workman, Kathleen A. Kane, Davide Pau, Gillian E. Marshall, Andrew C. Rankin, Julie Russell, Calum J. Redpath, John Norrie
Publikováno v:
Heart Rhythm. 6:445-451
Left ventricular systolic dysfunction (LVSD) is a risk factor for atrial fibrillation (AF), but the atrial cellular electrophysiological mechanisms in humans are unclear.This study sought to investigate whether LVSD in patients who are in sinus rhyth
Autor:
M.R.C.P. Andrew D. McGAVIGAN M.D., Elaine Clark, M.R.C.P. F. Russell Quinn Ph.D., F.R.C.P. Peter W. Macfarlane D.Sc, M.R.C.P. Andrew C. Rankin M.D.
Publikováno v:
Pacing and Clinical Electrophysiology. 30:998-1002
Background: There are several published algorithms for the prediction of accessory pathway (AP) location in the Wolff-Parkinson-White syndrome from the 12-lead electrocardiogram (ECG). Most depend on stepwise criteria, and minor disagreements between
Publikováno v:
Journal of Molecular and Cellular Cardiology
5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT(4) receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown. The whole-cell perforated pat