Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew C. Orcutt"'
Autor:
Anthony W. Stowers, Gregory E. D. Mullen, Andrew C. Orcutt, Aaron P. Miles, Jin Wang, May Awkal, Julie H. McArthur, Birgitte Giersing, Louis H. Miller, Siddhartha Mahanty, Carole A. Long, John R. Perreault, Anna P. Durbin, Olga Muratova, Elissa Malkin, Hong Zhou, Allan Saul, David Diemert
Publikováno v:
Infection and Immunity. 73:3677-3685
Apical membrane antigen 1 (AMA1), a polymorphic merozoite surface protein, is a leading blood-stage malaria vaccine candidate. A phase 1 trial was conducted with 30 malaria-naïve volunteers to assess the safety and immunogenicity of the AMA1-C1 mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a74c4fe1d0999fb45bd5aa00e9cf9c
https://doi.org/10.1128/iai.73.6.3677-3685.2005
https://doi.org/10.1128/iai.73.6.3677-3685.2005
Publikováno v:
Photochemistry and Photobiology. 69:443-447
— The evaluation of the equilibrium constants for charge-transfer complex formation has been of interest for five decades. During this time, absorption spectroscopy using Benesi-Hildebrand, or related methods, has been used to obtain the equilibriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6d300fc58a9efb5841ca7785e772e7
https://doi.org/10.1111/j.1751-1097.1999.tb03310.x
https://doi.org/10.1111/j.1751-1097.1999.tb03310.x
Autor:
Louis H. Miller, Donna Shaffer, Daming Zhu, Anna P. Durbin, Michael P. Fay, Joan Aebig, Anders Mogensen, Ruth D. Ellis, Kazutoyo Miura, David L. Narum, Andrew C. Orcutt, Carole A. Long, Laura B. Martin, Kelly M. Rausch, Yimin Wu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46094 (2012)
PLoS ONE, Vol 7, Iss 10, p e46094 (2012)
A Phase 1 dose escalating study was conducted in malaria naive adults to assess the safety, reactogenicity, and immunogenicity of the blood stage malaria vaccine BSAM2/Alhydrogel®+ CPG 7909. BSAM2 is a combination of the FVO and 3D7 alleles of recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e61050f01b8ef6da37e837c0b7e6b61
https://pubmed.ncbi.nlm.nih.gov/23056238
https://pubmed.ncbi.nlm.nih.gov/23056238
Autor:
Andrew C. Orcutt, Olga Muratova, Kazutoyo Miura, Carole A. Long, Birgitte Giersing, Louis H. Miller, Hong Zhou
At least a million people, mainly African children under 5 years old, still die yearly from malaria, and the burden of disease and death has increased. Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is one of the most promising blood-stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9aa4e2fb2489985468ff82283c4087
https://europepmc.org/articles/PMC2168362/
https://europepmc.org/articles/PMC2168362/
Publikováno v:
Vaccine. 26(2)
Enzyme linked immunosorbent assay (ELISA) has been widely used to measure antibody titers for evaluating the immunogenicity of a vaccine. However, there is as yet no generally accepted way of expressing the ELISA results in the case of experimental v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a36217a2401bc441f0a4cdb5c32578
https://pubmed.ncbi.nlm.nih.gov/18054414
https://pubmed.ncbi.nlm.nih.gov/18054414
Autor:
Donna Shaffer, Guanhong Song, Daming Zhu, Olga Muratova, Joan Aebig, Ruth D. Ellis, Kazutoyo Miura, Lynn Lambert, Kelly M. Rausch, Yimin Wu, Anna P. Durbin, Allan Saul, Carole A. Long, Elissa Malkin, Erica Fontes, David L. Narum, Michael P. Fay, Aaron P. Miles, Andrew C. Orcutt, Louis H. Miller, Siddhartha Mahanty
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 7, p e2636 (2008)
PLoS ONE, Vol 3, Iss 7, p e2636 (2008)
BackgroundPfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, dose escalating,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079801c20b59f4577ae05f8af40fe2e6
https://doi.org/10.1371/journal.pone.0002636
https://doi.org/10.1371/journal.pone.0002636
Phase 1 Study of Two Merozoite Surface Protein 1 (MSP142) Vaccines for Plasmodium falciparum Malaria
Autor:
Eveline L. Tierney, Elissa Malkin, Andrew C. Orcutt, Anthony W. Stowers, Michael P. Fay, Louis H. Miller, Siddhartha Mahanty, Laura B. Martin, Olga Muratova, Aaron P. Miles, Nicholas J. MacDonald, Carole A. Long, Sanjay Singh, Samuel E. Moretz, David L. Narum, Hong Zhou, Philip T. Leese, Lanling Zou, Ababacar Diouf, Allan Saul
Publikováno v:
PLoS Clinical Trials
Objectives: To assess the safety and immunogenicity of two vaccines, MSP142-FVO/Alhydrogel and MSP142-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum parasites. Design: A Phase 1 open-label, dose-escalating study. Setting: Quintiles Phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb525a7247ce971b905006a483dc7143
https://doi.org/10.1371/journal.pctr.0020012
https://doi.org/10.1371/journal.pctr.0020012