Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew C. Mansfield"'
Publikováno v:
Journal of Flow Chemistry. 5:148-150
The catalyzed and uncatalyzed preparation of ethyl levulinate from levulinic acid and ethanol is presented. In the case of acid-catalyzed reactions, conditions were optimized in batch using microwave heating and then scaled-up using continuousflow pr
Publikováno v:
Journal of Flow Chemistry. 2:47-51
A highly scalable and efficient flow-system has been developed to perform the catalyzed acetylation of alcohols and phenols, such as salicylic acid, at room temperature in excellent yield. The volumetric throughput and the amount of product can be in
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 1150-1157 (2011)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
A product-scalable, catalytically mediated flow system has been developed to perform Suzuki–Miyaura reactions under a microwave heating regime, in which the volumetric throughput of a Pd-supported silica monolith can be used to increase the quantit
Publikováno v:
Journal of Porous Materials. 18:501-508
For applications as catalyst supports in flow reactors, porous silica monoliths require a combination of connected pores of micron-scale to enable fluid flow plus nm-scale pores to enable high catalyst area and activity. We have synthesised a range p
Publikováno v:
Tetrahedron Letters. 51:1026-1029
The [3+2] dipolar cycloaddition reactions of the unstabilised azomethine ylide precursor benzyl(methoxymethyl)(trimethylsilylmethyl)amine with 12 electron-deficient alkenes in the presence of catalytic trifluoroacetic acid are examined under continuo
Publikováno v:
Angewandte Chemie. 121:4077-4081
Autor:
Francesca Perrucio, M. Abid Masood, Graham Smith, Charles E. Mowbray, M. J. Gardner, Helen Kenyon-Edwards, Charlotte Alice Louise Lane, Rhys M. Jones, Andrew Simon Bell, Wai L. Liu, Andrew C. Mansfield, Matthew D. Selby, Nick Clarke, Christopher D. Brown, Rachel Osborne
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(21)
We describe the identification of a potent, selective lead series that shows antagonism against the human histamine H4 receptor from thirteen actives identified in an HTS as part of a hit to lead program. By focusing on ligand efficiency and concurre
Publikováno v:
Angewandte Chemie (International ed. in English). 48(22)
Mehrstufig und fliesend: Das Seyferth-Gilbert-Reagens 1 wurde in einem Durchfluss-System zur schnellen Synthese von terminalen Alkinen eingesetzt. Weitere Anwendung fand das System bei der Synthese des Triazols 3 aus dem Alkohol 2 in einer dreistufig
Autor:
Andrew C. Mansfield, Paul D. I. Fletcher, Stephen J. Haswell, Grant Chaplain, Stephen M. Kelly
Publikováno v:
Australian Journal of Chemistry. 66:208
We show how in-line Raman spectroscopy can be used to monitor both reactant and product concentrations for a heterogeneously catalysed Suzuki cross reaction operating in continuous flow. The flow system consisted of an HPLC pump to drive a homogeneou