Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Andrew C. Keates"'
Publikováno v:
PLoS ONE, Vol 8, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/e96d09887d1d4328921efdb2c71cd2c2
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2323
Spontaneous tumor regression following bacterial infection has been observed for hundreds of years. These observations along with anecdotal medical findings in 1890s led to the development of Coley's "toxins," consisting of killed Streptococcus pyoge
Publikováno v:
RNA Scaffolds ISBN: 9781071614983
Spontaneous tumor regression following bacterial infection has been observed for hundreds of years. These observations along with anecdotal medical findings in 1890s led to the development of Coley's "toxins," consisting of killed Streptococcus pyoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88e1e2883ed50a29b18cc119f341018
https://doi.org/10.1007/978-1-0716-1499-0_19
https://doi.org/10.1007/978-1-0716-1499-0_19
Publikováno v:
Oncotarget
Recent advances in cancer genomics have opened up unlimited potential for treating cancer by directly targeting culprit genes. However, novel delivery methods are needed in order for this potential to be translated into clinically viable treatments f
Autor:
Jie Lin Zhang, Chiang J. Li, Thu Nguyen, Johannes Fruehauf, Andrew C. Keates, Hongnian Guo, C Inal
Publikováno v:
Gene Therapy. 18:95-105
RNA interference (RNAi) has been established as an important research tool that carries great potential for gene therapy. However, targeted induction of RNAi in vivo has met with significant challenges. In this study, a novel pSLS plasmid capable of
Autor:
Beat M. Künzli, K. Becker, Sarah Keates, Sunil A Sheth, Pelayo Correa, Maria Blanca Piazuelo, Richard M. Peek, Ciaran P. Kelly, Sanjeev Tummala, Eva Csizmadia, Simon C. Robson, Judith Romero-Gallo, Andrew C. Keates
Publikováno v:
Infection and Immunity. 76:3992-3999
Chronic infection with the gastric pathogen Helicobacter pylori significantly increases the risk of developing atrophic gastritis, peptic ulcer disease, and gastric adenocarcinoma. H. pylori strains that possess the cag pathogenicity island, which tr
Publikováno v:
Biotechnology and Genetic Engineering Reviews. 25:113-128
Since its discovery in 1998 RNA interference (RNAi), a potent and highly selective gene silencing mechanism, has revolutionized the field of biological science. The ability of RNAi to specifically down-regulate the expression of any cellular protein
Publikováno v:
Pharmacogenomics. 8:867-871
Cequent Pharmaceuticals, Inc. is a recently established biopharmaceutical company that aims to develop clinically compatible therapies based on RNAi, a potent gene-silencing mechanism discovered in 1998. The company’s proprietary technology, transk
Publikováno v:
Gut. 54:1363-1369
Background and aims: Helicobacter pylori, in particular cytotoxin associated gene (cag)+ strains, have been shown to enhance gastric epithelial cell proliferation in vivo, an effect that likely contributes to gastric carcinogenesis. Early growth resp
Publikováno v:
Journal of Biological Chemistry. 279:25179-25188
Flagellin, a specific ligand for Toll-like receptor 5 (TLR5), is a molecular pattern associated with several bacterial species. Recently, TLR signaling has been intensively studied. However, TLR5-associated signaling in non-transformed colonocytes ha