Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Andrew C. Keates"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2323
Spontaneous tumor regression following bacterial infection has been observed for hundreds of years. These observations along with anecdotal medical findings in 1890s led to the development of Coley's "toxins," consisting of killed Streptococcus pyoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e01ab5cf735a224c97e3dc51941b0b25
https://pubmed.ncbi.nlm.nih.gov/34086287
https://pubmed.ncbi.nlm.nih.gov/34086287
Publikováno v:
RNA Scaffolds ISBN: 9781071614983
Spontaneous tumor regression following bacterial infection has been observed for hundreds of years. These observations along with anecdotal medical findings in 1890s led to the development of Coley's "toxins," consisting of killed Streptococcus pyoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88e1e2883ed50a29b18cc119f341018
https://doi.org/10.1007/978-1-0716-1499-0_19
https://doi.org/10.1007/978-1-0716-1499-0_19
Publikováno v:
PLoS ONE, Vol 8, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/e96d09887d1d4328921efdb2c71cd2c2
Autor:
Tanya Sperling, Monika Ołdak, Barbara Walch-Rückheim, Claudia Wickenhauser, John Doorbar, Herbert Pfister, Magdalena Malejczyk, Sławomir Majewski, Andrew C Keates, Sigrun Smola
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002833 (2012)
Infection with genus beta human papillomaviruses (HPV) is implicated in the development of non-melanoma skin cancer. This was first evidenced for HPV5 and 8 in patients with epidermodysplasia verruciformis (EV), a genetic skin disease. So far, it has
Externí odkaz:
https://doaj.org/article/81898d1f4f5346f598d0d19c9c2dbe17
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43628 (2012)
The cancer stem cell (CSC) model posits the presence of a small number of CSCs in the heterogeneous cancer cell population that are ultimately responsible for tumor initiation, as well as cancer recurrence and metastasis. CSCs have been isolated from
Externí odkaz:
https://doaj.org/article/10dd6b7fba284a5aa1320ec67ee57328
Publikováno v:
Oncotarget
Recent advances in cancer genomics have opened up unlimited potential for treating cancer by directly targeting culprit genes. However, novel delivery methods are needed in order for this potential to be translated into clinically viable treatments f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f358e94a40498fb7f22f7459cf4f372f
https://doi.org/10.18632/oncotarget.490
https://doi.org/10.18632/oncotarget.490
Autor:
Jie Lin Zhang, Chiang J. Li, Thu Nguyen, Johannes Fruehauf, Andrew C. Keates, Hongnian Guo, C Inal
Publikováno v:
Gene Therapy. 18:95-105
RNA interference (RNAi) has been established as an important research tool that carries great potential for gene therapy. However, targeted induction of RNAi in vivo has met with significant challenges. In this study, a novel pSLS plasmid capable of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4206fea166f0fe6feed869abf68ea2
https://doi.org/10.1038/gt.2010.112
https://doi.org/10.1038/gt.2010.112
Autor:
Beat M. Künzli, K. Becker, Sarah Keates, Sunil A Sheth, Pelayo Correa, Maria Blanca Piazuelo, Richard M. Peek, Ciaran P. Kelly, Sanjeev Tummala, Eva Csizmadia, Simon C. Robson, Judith Romero-Gallo, Andrew C. Keates
Publikováno v:
Infection and Immunity. 76:3992-3999
Chronic infection with the gastric pathogen Helicobacter pylori significantly increases the risk of developing atrophic gastritis, peptic ulcer disease, and gastric adenocarcinoma. H. pylori strains that possess the cag pathogenicity island, which tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9ba9f5f8e9d1edd9cde31ab8eec7d0
https://doi.org/10.1128/iai.00584-08
https://doi.org/10.1128/iai.00584-08
Publikováno v:
Biotechnology and Genetic Engineering Reviews. 25:113-128
Since its discovery in 1998 RNA interference (RNAi), a potent and highly selective gene silencing mechanism, has revolutionized the field of biological science. The ability of RNAi to specifically down-regulate the expression of any cellular protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95096415e6ccdfa6278546097ca31f73
https://doi.org/10.5661/bger-25-113
https://doi.org/10.5661/bger-25-113
Publikováno v:
Pharmacogenomics. 8:867-871
Cequent Pharmaceuticals, Inc. is a recently established biopharmaceutical company that aims to develop clinically compatible therapies based on RNAi, a potent gene-silencing mechanism discovered in 1998. The company’s proprietary technology, transk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36278469e9fc32c8a26286a40a1fcb58
https://doi.org/10.2217/14622416.8.7.867
https://doi.org/10.2217/14622416.8.7.867