Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Andrew C. Doxey"'
Autor:
Briallen Lobb, Matthew C. Lee, Christi L. McElheny, Yohei Doi, Kristin Yahner, Alejandro Hoberman, Judith M. Martin, Jeremy A. Hirota, Andrew C. Doxey, Nader Shaikh
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Acute otitis media (AOM) is the most common childhood bacterial infectious disease requiring antimicrobial therapy. Most cases of AOM are caused by translocation of Streptococcus pneumoniae or Haemophilus influenzae from the nasopharynx to t
Externí odkaz:
https://doaj.org/article/4db5dbea45d049d69db4920aeb5b1bf5
Autor:
Harold P. Hodgins, Pengsheng Chen, Briallen Lobb, Xin Wei, Benjamin J. M. Tremblay, Michael J. Mansfield, Victoria C. Y. Lee, Pyung-Gang Lee, Jeffrey Coffin, Ana T. Duggan, Alexis E. Dolphin, Gabriel Renaud, Min Dong, Andrew C. Doxey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The analysis of microbial genomes from human archaeological samples offers a historic snapshot of ancient pathogens and provides insights into the origins of modern infectious diseases. Here, we analyze metagenomic datasets from 38 human arc
Externí odkaz:
https://doaj.org/article/d801818533014c76b1548ef357de2773
Autor:
Nadia Milad, Matthew F. Fantauzzi, Joshua J.C. McGrath, Steven P. Cass, Danya Thayaparan, Peiyao Wang, Sam Afkhami, Jennifer A. Aguiar, Kjetil Ask, Andrew C. Doxey, Martin R. Stampfli, Jeremy A. Hirota
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Rationale Despite its increasingly widespread use, little is known about the impact of cannabis smoking on the response to viral infections like influenza A virus (IAV). Many assume that cannabis smoking will disrupt antiviral responses in a manner s
Externí odkaz:
https://doaj.org/article/701d31614b5d4540a65bf088276e3fa6
Autor:
Songhai Tian, Xiaozhe Xiong, Ji Zeng, Siyu Wang, Benjamin Jean-Marie Tremblay, Peng Chen, Baohua Chen, Min Liu, Pengsheng Chen, Kuanwei Sheng, Daniel Zeve, Wanshu Qi, David T. Breault, César Rodríguez, Ralf Gerhard, Rongsheng Jin, Andrew C. Doxey, Min Dong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Toxin B (TcdB) is a major exotoxin responsible for diseases associated with C. difficile infection. Here, Tian et al. show that several TcdB subtypes do not recognize the established FZD receptors, and identify a different host protein (TFPI) as a re
Externí odkaz:
https://doaj.org/article/794a66b7501d4c9db6602d45ebb015c0
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13955- (2023)
Cytokinin is a major phytohormone that has been used in agriculture as a plant-growth stimulating compound since its initial discovery in the 1960s. Isopentenyl transferase (IPT) is a rate-limiting enzyme for cytokinin biosynthesis, which is produced
Externí odkaz:
https://doaj.org/article/bfdb410e13f542d9a41a81ea20348ac4
Autor:
Seiji N. Sugiman-Marangos, Shivneet K. Gill, Michael J. Mansfield, Kathleen E. Orrell, Andrew C. Doxey, Roman A. Melnyk
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Toxic proteins are responsible for the disease symptoms accompanying bacterial infections. Sugiman-Marangos et al. report crystal structures of two diphtheria toxin homologs, therefore providing structural insights into this family of toxins and the
Externí odkaz:
https://doaj.org/article/d2c33bb959a14000812163c9bb5ae287
Autor:
Yechan Kim, Vincent Hou, Ryan D. Huff, Jennifer A. Aguiar, Spencer Revill, Nicholas Tiessen, Quynh Cao, Matthew S. Miller, Mark D. Inman, Kjetil Ask, Andrew C. Doxey, Jeremy A. Hirota
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Introduction Over 300 million people in the world live with asthma, resulting in 500,000 annual global deaths with future increases expected. It is estimated that around 50–80% of asthma exacerbations are due to viral infections. Currently
Externí odkaz:
https://doaj.org/article/1c48fa1db9b840728ed1afd05afc5735
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background A substantial fraction of genes identified within bacterial genomes encode proteins of unknown function. Identifying which of these proteins represent potential virulence factors, and mapping their key virulence determinants, is a
Externí odkaz:
https://doaj.org/article/5a80211491ed4afea061680d98b1e9e7
Publikováno v:
Viruses, Vol 15, Iss 5, p 1116 (2023)
Phycodnaviridae are large double-stranded DNA viruses, which facilitate studies of host–virus interactions and co-evolution due to their prominence in algal infection and their role in the life cycle of algal blooms. However, the genomic interpreta
Externí odkaz:
https://doaj.org/article/366babd1a49b4139ad2fe05de9a49760
Autor:
Daniel Richard, Pushpanathan Muthuirulan, Jennifer Aguiar, Andrew C. Doxey, Arinjay Banerjee, Karen Mossman, Jeremy Hirota, Terence D. Capellini
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104614- (2022)
Summary: The angiotensin-converting enzyme 2 (ACE2) protein is a key catalytic regulator of the renin-angiotensin system (RAS), involved in fluid homeostasis and blood pressure modulation. ACE2 also serves as a cell-surface receptor for some coronavi
Externí odkaz:
https://doaj.org/article/44c0b628ea214c9c84b80ab8741b75bf