A retrospective analysis of pathogen profile, antimicrobial resistance and mortality in neonatal hospital-acquired bloodstream infections from 2009-2018 at Tygerberg Hospital, South Africa.

Autor: Kessendri Reddy, Adrie Bekker, Andrew C Whitelaw, Tonya M Esterhuizen, Angela Dramowski

Publikováno v: PLoS ONE, Vol 16, Iss 1, p e0245089 (2021)

BackgroundAnalysis of hospital-acquired bloodstream infection (HA-BSI) trends is important to monitor emerging antimicrobial resistance (AMR) threats and guide empiric antibiotic choices.MethodsA retrospective 10-year review of neonatal HA-BSI was pe

Externí odkaz: https://doaj.org/article/fb952fa64caf4ca1ade322d623afe95b

SafeHANDS: A Multimodal Hand Hygiene Intervention in a Resource-Limited Neonatal Unit

Autor: Angela Dramowski, Louisa M. Erasmus, Marina Aucamp, Aaqilah Fataar, Mark F. Cotton, Susan E. Coffin, Adrie Bekker, Andrew C. Whitelaw

Publikováno v: Tropical Medicine and Infectious Disease, Vol 8, Iss 1, p 27 (2022)

Background: Hand hygiene (HH) is a cornerstone of programmes to prevent healthcare associated infections (HAI) globally, but HH interventions are seldom reported from African neonatal units. Methods: We conducted a quasi-experimental study evaluating

Externí odkaz: https://doaj.org/article/f7ebb48806c74ab7857043b58d14ef50

Molecular characterization of multidrug-resistant Klebsiella pneumoniae and Escherichia coli harbouring extended spectrum beta-lactamases and carbapenemases genes at a tertiary hospital, Kenya

Autor: Daniel Maina, Gunturu Revathi, Andrew C. Whitelaw

Publikováno v: Microbiologia Medica, Vol 32, Iss 4 (2017)

Background. Multidrug-resistant (MDR) Gram negative rods are increasingly being reported in sub-Saharan Africa. Molecular investigations play an important role, alongside other measures, in controlling nosocomial infections attributed to these organi

Externí odkaz: https://doaj.org/article/3a914e619df2411299f1f218c8331780

Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study

Autor: Rebecca Milton, David Gillespie, Calie Dyer, Khadijeh Taiyari, Maria J Carvalho, Kathryn Thomson, Kirsty Sands, Edward A R Portal, Kerenza Hood, Ana Ferreira, Thomas Hender, Nigel Kirby, Jordan Mathias, Maria Nieto, William J Watkins, Delayehu Bekele, Mahlet Abayneh, Semaria Solomon, Sulagna Basu, Ranjan K Nandy, Bijan Saha, Kenneth Iregbu, Fatima Z Modibbo, Stella Uwaezuoke, Rabaab Zahra, Haider Shirazi, Syed U Najeeb, Jean-Baptiste Mazarati, Aniceth Rucogoza, Lucie Gaju, Shaheen Mehtar, Andre N H Bulabula, Andrew C Whitelaw, Timothy R Walsh, Grace J Chan, Oludare Odumade, Rozina Ambachew, Zenebe Gebre Yohannes, Gesit Metaferia, Redeat Workneh, Tefera Biteye, Yahya Zekaria Mohammed, Alula M Teklu, Balkachew Nigatu, Wendimagegn Gezahegn, Partha Sarathi Chakravorty, Sharmi Naha, Anuradha Mukherjee, Khairiyya Muhammad Umar, Asunugwo Vivian Akunna, Queen Nsude, Ifeoma Uke, Mary-Joe Okenu, Chinenye Akpulu, Chukwuemeka Mmadueke, Samuel Yakubu, Lamidi Audu, Nura Idris, Safiya Gambo, Jamila Ibrahim, Edwin Chinago, Ashiru Yusuf, Shamsudden Gwadabe, Adeola Adeleye, Muhammad Aliyu, Amina Muhammad, Aishatu Kassim, Aisha Sani Mukaddas, Rashida Yakubu Khalid, Fatima Ibrahim Alkali, Maryam Yahaya Muhammad, Fatima Muhammad Tukur, Surayya Mustapha Muhammad, Adeola Shittu, Murjanatu Bello, Fatima Habib Sa ad, Shaheed Zulfiqar, Adil Muhammad, Muhammad Hilal Jan, Lauren Paterson

Background\udNeonatal sepsis is a primary cause of neonatal mortality and is an urgent global health concern, especially within low-income and middle-income countries (LMICs), where 99% of global neonatal mortality occurs. The aims of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cec59aff3258d66c0750e53f6f1f57
https://orca.cardiff.ac.uk/id/eprint/149183/1/PIIS2214109X22000432.pdf

A comparison of cases of paediatric-onset and adult-onset cryptococcosis detected through population-based surveillance, 2005–2007

Autor: Susan T, Meiring, Vanessa C, Quan, Cheryl, Cohen, Halima, Dawood, Alan S, Karstaedt, Kerrigan M, McCarthy, Andrew C, Whitelaw, Nelesh P, Govender

Publikováno v: AIDS. 26:2307-2314

OBJECTIVE We compared the epidemiology of laboratory-confirmed paediatric cryptococcal disease with adult-onset disease in the South African population. METHODS The study was an active, prospective, population-based, laboratory-based surveillance in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a8713bca5bb06a452f03f3e4c86e0d
https://doi.org/10.1097/qad.0b013e3283570567