Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrew C R Epstein"'
Autor:
Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe
Publikováno v:
PLoS Biology, Vol 2, Iss 10, p e289 (2004)
The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated alpha subunits of hypoxia-inducible factor (HIF). Although studies of VHL-defective renal carcinoma cells suggest the
Externí odkaz:
https://doaj.org/article/eb68e705940c425ca62a683545f28f74
Autor:
Jonathan N. Townend, Sagar N. Doshi, Andrew C R Epstein, Peter Ludman, Nigel P. Buller, Helen Routledge, Colin D. Chue
Publikováno v:
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 75(4)
Objectives: To determine the 3 year safety and efficacy of crush-stenting with paclitaxel-eluting stents. Background: The optimum two-stent strategy for treatment of coronary bifurcation lesions is undetermined. Crush-stenting is advocated to minimiz
Autor:
Christopher W. Pugh, Andrew C. R Epstein, Jonathan M. Gleadle, Kah Weng Lau, Peter J. Ratcliffe, Martin S. Taylor, Jonathan Hodgkin, Stuart K. Kim, Tammie Bishop, Delia O'Rourke, Min Jiang
Publikováno v:
Bishop, T, Lau, K W, Epstein, A C R, Kim, S K, Jiang, M, O'Rourke, D, Pugh, C W, Gleadle, J M, Taylor, M S, Hodgkin, J & Ratcliffe, P J 2004, ' Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans ', PLoS Biology, vol. 2, no. 10, pp. e289 . https://doi.org/10.1371/journal.pbio.0020289
PLoS Biology
Flinders University PURE
PLoS Biology, Vol 2, Iss 10, p e289 (2004)
PLoS Biology
Flinders University PURE
PLoS Biology, Vol 2, Iss 10, p e289 (2004)
The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated α subunits of hypoxia-inducible factor (HIF). Although studies of VHL-defective renal carcinoma cells suggest the exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4001c0e1fe709ee7848bfedd511fbd
https://www.pure.ed.ac.uk/ws/files/7944160/Genetic_analysis_of_pathways_regulated_by_the_von_Hippel_Lindau_tumor_suppressor_in_Caenorhabditis_elegans.pdf
https://www.pure.ed.ac.uk/ws/files/7944160/Genetic_analysis_of_pathways_regulated_by_the_von_Hippel_Lindau_tumor_suppressor_in_Caenorhabditis_elegans.pdf
Autor:
David R. Mole, Christopher J. Schofield, Robert Barstead, Norma Masson, Andrew C. R Epstein, Patrick H. Maxwell, Donald L. Hamilton, Mridul Mukherji, Luke A. McNeill, Ya-Min Tian, J F O'Rourke, Jonathan Hodgkin, Anu Dhanda, Jonathan M. Gleadle, Christopher W. Pugh, Panu Jaakkola, Eric Metzen, Kirsty S. Hewitson, Michael A Wilson, Peter J. Ratcliffe
Publikováno v:
Flinders University PURE
HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. Recent studies have defined posttranslational modification by prolyl hydroxylation as a key regulatory event that targets HIF-α subunits for proteasomal dest