Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Andrew C Issekutz"'
Autor:
Yin Ye, De-Tao Yin, Li Chen, Quansheng Zhou, Rulong Shen, Gang He, Qingtao Yan, Zhenyu Tong, Andrew C Issekutz, Charles L Shapiro, Sanford H Barsky, Haifan Lin, Jian-Jian Li, Jian-Xin Gao
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13406 (2010)
PIWIL2, a member of PIWI/AGO gene family, is expressed in the germline stem cells (GSCs) of testis for gametogenesis but not in adult somatic and stem cells. It has been implicated to play an important role in tumor development. We have previously re
Externí odkaz:
https://doaj.org/article/9a911db065244378b3e102cf91e5b5fd
Autor:
John J Heath, Fabian Käsermann, Beata Derfalvi, Sarah M. McAlpine, Andrew C. Issekutz, Sarah E. Roberts, Thomas B. Issekutz
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Intravenous immunoglobulin (IVIG) is an effective immunomodulatory treatment for immune dysregulation diseases. However, the mechanisms by which it reduces systemic inflammation are not well understood. NK cell cytotoxicity is decreased by IVIG in wo
Publikováno v:
Mediators of Inflammation, Vol 1, Iss 5, Pp 347-353 (1992)
The cytokines IL-1 and TNF-α are involved in inflammation and their production is stimulated by various agents, especially endotoxin (LPS). Here, using the human IL-1 receptor antagonist (IL-1RA) and a new monoclonal antibody (mAb 7F11) to rabbit TN
Externí odkaz:
https://doaj.org/article/dd504e70841145ea910d933bcdb43aab
Publikováno v:
Clinical Immunology. 161:373-383
Intravenous IgG (IVIG) therapy can be used for immunomodulation. IL-2 is an immunoregulatory cytokine. We evaluated IVIG modulation of human blood lymphocyte response to IL-2 and other cytokines. Neither IVIG nor low concentrations of IL-2 (3-30U/ml)
Autor:
Andrés Augusto Arias, Paola Capasso, Federica Barzaghi, Bertrand Boisson, Aziz Bousfiha, Jean-Laurent Casanova, Carmen Oleaga-Quintas, José Luis Franco, Luca Basso-Ricci, Jérémie Rosain, Stefania Giannelli, Claudia Sartirana, Roberta Caorsi, Maria Pia Cicalese, Jacinta Bustamante, Bénédicte Neven, Kerry Dobbs, Marta Benavides-Nieto, Yu Nee Lee, Anna Villa, Lucia Piceni Sereni, Jesús A. Álvarez-Álvarez, Benedetta Mazzi, Andrew C. Issekutz, Alessandro Aiuti, Francesca Dionisio, Nufar Marcus, Despina Moshous, Angelo Lombardo, Loïc Dupré, Stefano Volpi, Raz Somech, Laurène Pfajfer, Marcela Vélez, Luca Pavesi, Immacolata Brigida, Cristina Scielzo, Thomas B. Issekutz, Massimo Degano, Joëlle Khourieh, Serena Scala, Paolo Picco, Matteo Zoccolillo, Luigi D. Notarangelo, Marco Gattorno, Giuseppe Raiola
ARPC1B is a key factor for the assembly and maintenance of the ARP2/3 complex that is involved in actin branching from an existing filament. Germline biallelic mutations in ARPC1B have been recently described in 6 patients with clinical features of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05430ed184b064337b8db85cf18662fd
http://hdl.handle.net/11567/930064
http://hdl.handle.net/11567/930064
Autor:
James A. Deane, A. Richard Kitching, Andrew C. Issekutz, Zachary Chow, Michael J. Hickey, Clare L. V. Westhorpe, Maliha A. Alikhan, Latasha D. Abeynaike
Publikováno v:
The Journal of Immunology. 193:4934-4944
Regulatory T cells (Tregs) play critical roles in restricting T cell–mediated inflammation. In the skin, this is dependent on expression of selectin ligands required for leukocyte rolling in dermal microvessels. However, whether there are differenc
Autor:
Mohammad K. Eldomery, Olaug K. Rødningen, Cecilia Poli, Debra Canter, Berit Flatø, Ketil Heimdal, Nicholas L. Rider, Silje F. Jørgensen, Hasibe Artac, Hans Christian Erichsen, Francisco Javier Espinosa Rosales, Ivan K. Chinn, Alison A. Bertuch, Bo Yuan, Jordan S. Orange, Emily M. Mace, Wojciech Wiszniewski, Robert Lyle, Shalini N. Jhangiani, Tobias Gedde-Dahl, Carla M. Davis, Carl E. Allen, I. Celine Hanson, Magnus K. O. Burstedt, Thomas B. Issekutz, Mari Ann Kulseth, Yavuz Bayram, Eric A. Smith, Tram N. Cao, Stephen Jolles, Andrew C. Issekutz, Pubudu S. Samarakoon, Alice Y. Chan, Gozde Yesil, Eva Holmberg, Børre Fevang, Diana K. Bayer, John W. Belmont, Asbjørg Stray-Pedersen, Timothy J. Vece, Magdalena Walkiewicz, James R. Lupski, Ying Sheng, Trine Prescott, Liv T. N. Osnes, Cecilie F. Rustad, Nina Denisse Guerrero-Cursaru, Juan Carlos Aldave Becerra, Victor Wei Zhang, Philip M. Boone, Mohammad S. Ehlayel, Jason W. Caldwell, Tore G. Abrahamsen, José Luis Franco, Harshal Abhyankar, Henrik Hjorth-Hansen, Liliana Bezrodnik, Vegard Skogen, Nicola A.M. Wright, Lisa R. Forbes, Anne Grete Bechensteen, Christine R. Beck, Saul Oswaldo Lugo Reyes, Lee-Jun C. Wong, Shen Gu, Sarah K. Nicholas, Christina E. West, Filiz O. Seeborg, Mehmed M. Atik, Eric Boerwinkle, Luis A. Pedroza, Caterina Cancrini, Hanne Sørmo Sorte, Yaping Yang, Christine M. Eng, Richard A. Gibbs, Lenora M. Noroski, Alessandro Aiuti, Ender Karaca, Torstein Øverland, Claudia Milena Trujillo Vargas, Jordan K. Abbott, Geir E. Tjønnfjord, William T. Shearer, Javier Chinen, Ingunn Dybedal, Tomasz Gambin, Donna M. Muzny, Pål Aukrust, Ingvild Nordøy, María Soledad Caldirola, Jianhong Hu, Zeynep Coban Akdemir
Publikováno v:
The Journal of allergy and clinical immunology, vol 139, iss 1
WOS: 000393996800025
PubMed: 27577878
Background: Primary immunodeficiency diseases (PIDDs) are clinically and genetically heterogeneous disorders thus far associated with mutations in more than 300 genes. The clinical phenotypes derived fr
PubMed: 27577878
Background: Primary immunodeficiency diseases (PIDDs) are clinically and genetically heterogeneous disorders thus far associated with mutations in more than 300 genes. The clinical phenotypes derived fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abf0338cd9012533e4851a811cd28aa
https://escholarship.org/uc/item/8188960d
https://escholarship.org/uc/item/8188960d
Autor:
Fabio Candotti, Yongmei Liu, Amy S. Paller, G.A. Montealegre Sanchez, Huseyin Mehmet, Raphaela Goldbach-Mansky, Susan Moir, Anna M. Trier, Nicole Plass, S Hill, B Marrero, Mark Raffeld, Iren Horkayne-Szakaly, Sofia Rosenzweig, Ira Palmer, Thomas A. Fleisher, Michael A. DiMattia, Hye Sun Kuehn, Joshua J McElwee, Caterina P. Minniti, A.C. Steven, Steven M. Holland, Chyi-Chia Richard Lee, Manfred Boehm, Stephen R. Brooks, Yhu Chering Huang, Wanxia L. Tsai, Angelique Biancotto, Andrei Barysenka, Jason D. Hughes, Benito Gonzalez, Klaus Tenbrock, Joseph R. Fontana, Deborah L. Stone, Andrew C. Issekutz, Dan Yang, Helmut Wittkowski, Zuoming Deng, Dirk Foell, A Almeida de Jesus, Olcay Y. Jones, C. St. Hilaire, Shakuntala Gurprasad, Suzanne E. Ramsey, Daniel L. Kastner, D. Chapelle, Massimo Gadina, Hanna Kim, Edward W. Cowen, J.J. DiGiovanna, H. Kim, Paul T. Wingfield
Publikováno v:
New England Journal of Medicine. 371:507-518
BACKGROUND The study of autoinflammatory diseases has uncovered mechanisms underlying cytokine dysregulation and inflammation. METHODS We analyzed the DNA of an index patient with early-onset systemic inflammation, cutaneous vasculopathy, and pulmona
Autor:
Duncan Letenyi, Andrew C. Issekutz, Brianna McKelvie, Christine McCusker, Karina A. Top, Thomas B. Issekutz
Publikováno v:
Journal of Clinical Immunology. 34:267-271
IRAK-4 deficiency causes IL-1R and TLR signaling failure, resulting in minimal clinical features despite invasive bacterial infection. We report the course of a 7-year-old IRAK-4-deficient girl presenting in the first year with multiple occult Staphy
Autor:
Andrew C. Issekutz, Manel Juan, Damien Chaussabel, Huey Hsuan Chang, Pegah Ghandil, Laurent Abel, László Maródi, Jean-Laurent Casanova, Capucine Picard, Laia Alsina, Carlos Rodríguez-Gallego, Xiaoxia Li, Lucile Janniere, Horst von Bernuth, Imen Ben Mustapha, Margarida Guedes, Helen Chapel, Claudia Fortuny, Júlia Vasconcelos, Zhongbo Jin, Yoann Rose, Artur Bonito Vitor, Carlos Rodrigo, Anne Puel, Yildiz Camcioglu, Estibaliz Ruiz-Ortiz, Maya Chrabieh, Juan I. Aróstegui, Jacques Banchereau, Ben Zion Garty, Jordi Anton, Jordi Yagüe, Hui Xiao, Cheng-Lung Ku, María José Herrero-Mata, Nicolas Sirvent, Rungnapa Pankla, Mariona Pascal
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2008, 321 (5889), pp.691-6. ⟨10.1126/science.1158298⟩
Science, American Association for the Advancement of Science, 2008, 321 (5889), pp.691-6. 〈10.1126/science.1158298〉
Science, American Association for the Advancement of Science, 2008, 321 (5889), pp.691-6. ⟨10.1126/science.1158298⟩
Science, American Association for the Advancement of Science, 2008, 321 (5889), pp.691-6. 〈10.1126/science.1158298〉
International audience; MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to a broad range of pathogens in experimental settings of infection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b03fa197258e35b56f16ee9001674d3
https://ora.ox.ac.uk/objects/uuid:1e60df7a-baf4-4a83-a265-89dcf4cc3036
https://ora.ox.ac.uk/objects/uuid:1e60df7a-baf4-4a83-a265-89dcf4cc3036