Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Andrew C Doxey"'
Autor:
Michael J Mansfield, Benjamin J-M Tremblay, Ji Zeng, Xin Wei, Harold Hodgins, Jay Worley, Lynn Bry, Min Dong, Andrew C Doxey
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009181 (2020)
Clostridioides difficile is the major worldwide cause of antibiotic-associated gastrointestinal infection. A pathogenicity locus (PaLoc) encoding one or two homologous toxins, toxin A (TcdA) and toxin B (TcdB), is essential for C. difficile pathogeni
Externí odkaz:
https://doaj.org/article/ee195c9c70c64736827f09a77c84e596
Autor:
Michael Guo, Zun Liu, Jessie Willen, Cameron P Shaw, Daniel Richard, Evelyn Jagoda, Andrew C Doxey, Joel Hirschhorn, Terence D Capellini
Publikováno v:
eLife, Vol 6 (2017)
GWAS have identified hundreds of height-associated loci. However, determining causal mechanisms is challenging, especially since height-relevant tissues (e.g. growth plates) are difficult to study. To uncover mechanisms by which height GWAS variants
Externí odkaz:
https://doaj.org/article/8f603b92444e499599c4d55217f0523c
Autor:
Jiujun Cheng, Tatyana Romantsov, Katja Engel, Andrew C Doxey, David R Rose, Josh D Neufeld, Trevor C Charles
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172545 (2017)
The techniques of metagenomics have allowed researchers to access the genomic potential of uncultivated microbes, but there remain significant barriers to determination of gene function based on DNA sequence alone. Functional metagenomics, in which D
Externí odkaz:
https://doaj.org/article/77caf1414ef84624aaa3e28f7aad6726
Autor:
Angelika Böttger, Andrew C Doxey, Michael W Hess, Kristian Pfaller, Willi Salvenmoser, Rainer Deutzmann, Andreas Geissner, Barbara Pauly, Johannes Altstätter, Sandra Münder, Astrid Heim, Hans-Joachim Gabius, Brendan J McConkey, Charles N David
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52278 (2012)
The single-cell layered ectoderm of the fresh water polyp Hydra fulfills the function of an epidermis by protecting the animals from the surrounding medium. Its outer surface is covered by a fibrous structure termed the cuticle layer, with similarity
Externí odkaz:
https://doaj.org/article/3beaa3f1a0eb46c399639e61109a9fed
Autor:
Nadia Milad, Matthew F. Fantauzzi, Joshua J.C. McGrath, Steven P. Cass, Danya Thayaparan, Peiyao Wang, Sam Afkhami, Jennifer A. Aguiar, Kjetil Ask, Andrew C. Doxey, Martin R. Stampfli, Jeremy A. Hirota
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Rationale Despite its increasingly widespread use, little is known about the impact of cannabis smoking on the response to viral infections like influenza A virus (IAV). Many assume that cannabis smoking will disrupt antiviral responses in a manner s
Externí odkaz:
https://doaj.org/article/701d31614b5d4540a65bf088276e3fa6
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Figure from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab0cf07dbc910ec9d05a0fcb07970e6
https://doi.org/10.1158/1541-7786.22528076.v1
https://doi.org/10.1158/1541-7786.22528076.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Data from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ecf07276bacf58f9440d1b432cabf6
https://doi.org/10.1158/1541-7786.22528079.v1
https://doi.org/10.1158/1541-7786.22528079.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mitochondrial electron transport chain (ETC) activity. AML cells are distinct from their normal hematopoietic counterparts by this metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e265a1dc866eec9722f84e745fe748f
https://doi.org/10.1158/1541-7786.c.6545609
https://doi.org/10.1158/1541-7786.c.6545609
Autor:
Joseph F.A. Varga, Sascha R. Brunner, Grant Cheng, Daniel Min, Marc G. Aucoin, Andrew C. Doxey, Brian Dixon
Publikováno v:
Developmental and comparative immunology. 137
The overuse and misuse of antibiotics has led to the emergence of antibiotic-resistant bacterial species which remain a challenge to treat therapeutically. Novel and efficacious drugs are desperately needed to combat pathogens. One method to facilita
Autor:
Songhai Tian, Xiaozhe Xiong, Ji Zeng, Siyu Wang, Benjamin Jean-Marie Tremblay, Peng Chen, Baohua Chen, Min Liu, Pengsheng Chen, Kuanwei Sheng, Daniel Zeve, Wanshu Qi, David T. Breault, César Rodríguez, Ralf Gerhard, Rongsheng Jin, Andrew C. Doxey, Min Dong
Publikováno v:
Nature communications, vol 13, iss 1
Toxin B (TcdB) is a major exotoxin responsible for diseases associated with Clostridioides difficile infection. Its sequence variations among clinical isolates may contribute to the difficulty in developing effective therapeutics. Here, we investigat