Testing for Gluten-Related Disorders in Clinical Practice: The Role of Serology in Managing the Spectrum of Gluten Sensitivity

Autor: David Armstrong, Andrew C Don-Wauchope, Elena F Verdu

Publikováno v: Canadian Journal of Gastroenterology, Vol 25, Iss 4, Pp 193-197 (2011)

Immunoglobulin A tissue transglutaminase is the single most efficient serological test for the diagnosis of celiac disease. It is well known that immunoglobulin A tissue transglutaminase levels correlate with the degree of intestinal damage, and that

Externí odkaz: https://doaj.org/article/8970d8e62b244089bfef8fee0a774d5a

A Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients

Autor: Meera Shanmuganathan, Andrew C. Don-Wauchope, Holly Philbrick, David S. Wishart, Zachary Kroezen, Mohammad Omair Sarfaraz, Marco Puglia, Richel Poon, Philip Britz-McKibbin

Publikováno v: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)

Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4183d41b412aa6864844e96acbbf92f5
https://doi.org/10.3389/fmolb.2021.676349

Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children

Autor: Lyne Cloutier, G. V. Ramesh Prasad, George K. Dresser, Steven E. Gryn, Kara Nerenberg, Sonia Butalia, Alexander A. Leung, Andrew C. Don-Wauchope, Vincent Woo, Karen C. Tran, Simon L. Bacon, Laura M. Kuyper, Andrew L. Pipe, Marcel Ruzicka, George Honos, Milan Gupta, Janusz Feber, Richard Lewanczuk, Pavel Hamet, Gordon W. Moe, Kerry McBrien, Kevin C. Harris, Evelyne Rey, Theodore Wein, Mike Sharma, Donna McLean, Tavis S. Campbell, Ally P.H. Prebtani, Michael Roerecke, Robert A. Hegele, Peter Bolli, Janis M. Dionne, Swapnil Hiremath, Raj Padwal, Geneviève Benoit, Michel Vallée, Simon W. Rabkin, Guy Tremblay, Stella S. Daskalopoulou, S. Brian Penner, Sheldon W. Tobe, Thalia S. Field, Janusz Kaczorowski, Laura A. Magee, Ernesto L. Schiffrin, Meranda Nakhla, Charlotte Jones, Kaberi Dasgupta, Richard E. Gilbert, Anne-Marie Côté, JoAnne Arcand, Ross D. Feldman, Jean Grégoire, Tabassum Firoz, Alexander G. Logan, Michael D. Hill, Steven A. Grover, Alain Milot, Jonathan Y. Gabor, Peter Selby, Luc Trudeau, Philip A. McFarlane, Ellen Burgess, Patrice Lindsay, Maxime Lamarre-Cliche, Ross T. Tsuyuki, Praveena Sivapalan, Norman R.C. Campbell, Jonathan G. Howlett, Kim L. Lavoie, Anne Fournier, Doreen M. Rabi, Kelly B. Zarnke, Lawrence A. Leiter, Paul Oh, Cedric Edwards, Robert J. Herman, Raymond R. Townsend, Mark Gelfer, Gregory A. Kline, Ashkan Shoamanesh, Luc Poirier

Publikováno v: Nerenberg, K A, Zarnke, K B, Leung, A A, Dasgupta, K, Butalia, S, McBrien, K, Harris, K C, Nakhla, M, Cloutier, L, Gelfer, M, Lamarre-Cliche, M, Milot, A, Bolli, P, Tremblay, G, McLean, D, Padwal, R S, Tran, K C, Grover, S, Rabkin, S W, Moe, G W, Howlett, J G, Lindsay, P, Hill, M D, Sharma, M, Field, T, Wein, T H, Shoamanesh, A, Dresser, G K, Hamet, P, Herman, R J, Burgess, E, Gryn, S E, Grégoire, J C, Lewanczuk, R, Poirier, L, Campbell, T S, Feldman, R D, Lavoie, K L, Tsuyuki, R T, Honos, G, Prebtani, A P H, Kline, G, Schiffrin, E L, Don-Wauchope, A, Tobe, S W, Gilbert, R E, Leiter, L A, Jones, C, Woo, V, Hegele, R A, Selby, P, Pipe, A, McFarlane, P A, Oh, P, Gupta, M, Bacon, S L, Kaczorowski, J, Trudeau, L, Campbell, N RC, Hiremath, S, Roerecke, M, Arcand, J, Ruzicka, M, Prasad, G V R, Vallée, M, Edwards, C, Sivapalan, P, Penner, S B, Fournier, A, Benoit, G, Feber, J, Dionne, J, Magee, L A, Logan, A G, Côté, A-M, Rey, E, Firoz, T, Kuyper, L M, Gabor, J Y, Townsend, R R, Rabi, D M & Daskalopoulou, S S 2018, ' Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children ', Canadian Journal of Cardiology . https://doi.org/10.1016/j.cjca.2018.02.022

Hypertension Canada provides annually-updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension in adults and children. This year, the adult and pediatric guidelines are combined in one document. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcc1108bc80632b46250a8df9f500cb
https://doi.org/10.1016/j.cjca.2018.02.022

Point-of-care testing (POCT) and evidence-based laboratory medicine (EBLM) – does it leverage any advantage in clinical decision making?

Autor: Andrew C. Don-Wauchope, Christopher Florkowski, Karina Rodriguez-Capote, Julien Wils, Nuria Giménez, Annalise E Zemlin

Publikováno v: Critical Reviews in Clinical Laboratory Sciences. 54:471-494

Point-of-care testing (POCT) is the analysis of patient specimens outside the clinical laboratory, near or at the site of patient care, usually performed by clinical staff without laboratory training, although it also encompasses patient self-monitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0e62658882a50332ed675a74e97ffe
https://doi.org/10.1080/10408363.2017.1399336

Frameshift mutation in the APOA5 gene causing hypertriglyceridemia in a Pakistani family: Management and considerations for cardiovascular risk

Autor: Andrew C. Don-Wauchope, Guillaume Paré, Katherine M. Morrison, Michael Chong, Sébastien Thériault, Ricky Lali

Publikováno v: Journal of Clinical Lipidology. 10:1272-1277

We report a novel homozygous apolipoprotein A5 (APOA5) frameshift mutation (c.G425del-C, p.Arg143AlafsTer57) identified in a 12-year-old boy of Pakistani origin with severe hypertriglyceridemia (up to 35 mmol/L) and type V hyperlipoproteinemia. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14c11db1f5f571fde8fa09ab18d4f17
https://doi.org/10.1016/j.jacl.2016.07.009