Characterisation of mobile colistin resistance genes (mcr-3 and mcr-5) in river and storm water in regions of the Western Cape of South Africa

Autor: Yolandi Snyman, Andrew C. Whitelaw, Jo M. Barnes, Motlatji R. B. Maloba, Mae Newton-Foot

Publikováno v: Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-9 (2021)

Abstract Background Colistin is regarded as a last-resort antimicrobial against multi-drug resistant Gram-negative bacteria (GNB), therefore the dissemination of colistin resistance in the environment is of great concern. Horizontal transfer of mobil

Externí odkaz: https://doaj.org/article/cb16954c36354fa888cd74172221b099

SafeHANDS: A Multimodal Hand Hygiene Intervention in a Resource-Limited Neonatal Unit

Autor: Angela Dramowski, Louisa M. Erasmus, Marina Aucamp, Aaqilah Fataar, Mark F. Cotton, Susan E. Coffin, Adrie Bekker, Andrew C. Whitelaw

Publikováno v: Tropical Medicine and Infectious Disease, Vol 8, Iss 1, p 27 (2022)

Background: Hand hygiene (HH) is a cornerstone of programmes to prevent healthcare associated infections (HAI) globally, but HH interventions are seldom reported from African neonatal units. Methods: We conducted a quasi-experimental study evaluating

Externí odkaz: https://doaj.org/article/f7ebb48806c74ab7857043b58d14ef50

Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study)

Autor: Yolandi Snyman, Andrew C. Whitelaw, Motlatji R.B. Maloba, Anneke C. Hesseling, Mae Newton-Foot

Publikováno v: Southern African Journal of Infectious Diseases, Vol 36, Iss 1, Pp e1-e4 (2021)

Colistin is a last-resort antibiotic against multidrug-resistant, Gram-negative bacteria. Colistin resistance has been described in the clinical settings in South Africa. However, information on carriage of these bacteria in communities is limited. T

Externí odkaz: https://doaj.org/article/da79d6f6c68b41868c98efe87ad106c2

The effect of storage conditions on microbial communities in stool.

Autor: Kristien Nel Van Zyl, Andrew C Whitelaw, Mae Newton-Foot

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227486 (2020)

Microbiome research has experienced a surge of interest in recent years due to the advances and reduced cost of next-generation sequencing technology. The production of high quality and comparable data is dependent on proper sample collection and sto

Externí odkaz: https://doaj.org/article/8ade3bf9b4ca4883b8a8b705ddab6d4d

Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study

Autor: Rebecca Milton, David Gillespie, Calie Dyer, Khadijeh Taiyari, Maria J Carvalho, Kathryn Thomson, Kirsty Sands, Edward A R Portal, Kerenza Hood, Ana Ferreira, Thomas Hender, Nigel Kirby, Jordan Mathias, Maria Nieto, William J Watkins, Delayehu Bekele, Mahlet Abayneh, Semaria Solomon, Sulagna Basu, Ranjan K Nandy, Bijan Saha, Kenneth Iregbu, Fatima Z Modibbo, Stella Uwaezuoke, Rabaab Zahra, Haider Shirazi, Syed U Najeeb, Jean-Baptiste Mazarati, Aniceth Rucogoza, Lucie Gaju, Shaheen Mehtar, Andre N H Bulabula, Andrew C Whitelaw, Timothy R Walsh, Grace J Chan, Oludare Odumade, Rozina Ambachew, Zenebe Gebre Yohannes, Gesit Metaferia, Redeat Workneh, Tefera Biteye, Yahya Zekaria Mohammed, Alula M Teklu, Balkachew Nigatu, Wendimagegn Gezahegn, Partha Sarathi Chakravorty, Sharmi Naha, Anuradha Mukherjee, Khairiyya Muhammad Umar, Asunugwo Vivian Akunna, Queen Nsude, Ifeoma Uke, Mary-Joe Okenu, Chinenye Akpulu, Chukwuemeka Mmadueke, Samuel Yakubu, Lamidi Audu, Nura Idris, Safiya Gambo, Jamila Ibrahim, Edwin Chinago, Ashiru Yusuf, Shamsudden Gwadabe, Adeola Adeleye, Muhammad Aliyu, Amina Muhammad, Aishatu Kassim, Aisha Sani Mukaddas, Rashida Yakubu Khalid, Fatima Ibrahim Alkali, Maryam Yahaya Muhammad, Fatima Muhammad Tukur, Surayya Mustapha Muhammad, Adeola Shittu, Murjanatu Bello, Fatima Habib Sa ad, Shaheed Zulfiqar, Adil Muhammad, Muhammad Hilal Jan, Lauren Paterson

Background\udNeonatal sepsis is a primary cause of neonatal mortality and is an urgent global health concern, especially within low-income and middle-income countries (LMICs), where 99% of global neonatal mortality occurs. The aims of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cec59aff3258d66c0750e53f6f1f57
https://orca.cardiff.ac.uk/id/eprint/149183/1/PIIS2214109X22000432.pdf