Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Andrew C, Warden"'
Autor:
Raquel A. Rocha, Liam A. Wilson, Brett D. Schwartz, Andrew C. Warden, Luke W. Guddat, Robert E. Speight, Lara Malins, Gerhard Schenk, Colin Scott
Publikováno v:
Catalysts, Vol 14, Iss 7, p 399 (2024)
Synthetic nicotinamide biomimetics (NCBs) have emerged as alternatives to the use of natural cofactors. The relatively low cost and ease of manufacture of NCBs may enable the scaling of biocatalytic reactions to produce bulk chemicals (e.g., biofuels
Externí odkaz:
https://doaj.org/article/f233fd543a43465c88348977a4dee2f2
Autor:
Sundara M. U. P. Mawalagedera, Cecile Gueidan, Matthew Taylor, Andrew C. Warden, Juanita Rodriguez
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 145 (2022)
Small metabolites and venom metabolites produced by insects are known to exhibit biological activity. These metabolites could be used to develop natural product-based therapeutics. To screen for these metabolites, insects must be collected and accura
Externí odkaz:
https://doaj.org/article/27ca6eff63bc4700ad9c7f1c1ec50ded
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Lichen associations, a classic model for successful and sustainable interactions between micro-organisms, have been studied for many years. However, there are significant gaps in our understanding about how the lichen symbiosis operates at the molecu
Externí odkaz:
https://doaj.org/article/1a8d1e6f95b344f2bb722f78f3ed119f
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
Autor:
Rhys Grinter, Blair Ney, Rajini Brammananth, Christopher K. Barlow, Paul R. F. Cordero, David L. Gillett, Thierry Izoré, Max J. Cryle, Liam K. Harold, Gregory M. Cook, George Taiaroa, Deborah A. Williamson, Andrew C. Warden, John G. Oakeshott, Matthew C. Taylor, Paul K. Crellin, Colin J. Jackson, Ralf B. Schittenhelm, Ross L. Coppel, Chris Greening
Publikováno v:
mSystems, Vol 5, Iss 3 (2020)
ABSTRACT F420 is a low-potential redox cofactor used by diverse bacteria and archaea. In mycobacteria, this cofactor has multiple roles, including adaptation to redox stress, cell wall biosynthesis, and activation of the clinical antitubercular prodr
Externí odkaz:
https://doaj.org/article/b31841d86def486ba529324116760dbf
Publikováno v:
Metabolomics. 19
Introduction Nuclear magnetic resonance (NMR) is widely used in metabolomics but it focusses on 1H over other NMR-active nuclei. Objectives To evaluate the potential of alternative NMR-sensitive nuclei to generate useful metabolomic data. Method Prot
Autor:
F. Hafna Ahmed, Alessandro T. Caputo, Nigel G. French, Thomas S. Peat, Jason Whitfield, Andrew C. Warden, Janet Newman, Colin Scott
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:599-612
Anthozoan chromoproteins are highly pigmented, diversely coloured and readily produced in recombinant expression systems. While they are a versatile and powerful building block in synthetic biology for applications such as biosensor development, they
Autor:
Adam J. Olszewski, Damien Kee, Clare L. Scott, Shirley D'Sa, Marie José Kersten, Ibrahim Tohidi-Esfahani, Carl Harrington, Ruth Spearing, Judith Trotman, Peter Liburdi deNardis, Maria Lia Palomba, Stephen Opat, Marita Black, Javier Haurat, Andrew C. Warden, Elena Malunis
Publikováno v:
American journal of hematology, 96(6), E218-E222. Wiley-Liss Inc.
Autor:
Blair Ney, Carlo R. Carere, Richard Sparling, Thanavit Jirapanjawat, Matthew B. Stott, Colin J. Jackson, John G. Oakeshott, Andrew C. Warden, Chris Greening
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
F420 is a microbial cofactor that mediates a wide range of physiologically important and industrially relevant redox reactions, including in methanogenesis and tetracycline biosynthesis. This deazaflavin comprises a redox-active isoalloxazine headgro
Externí odkaz:
https://doaj.org/article/8fdbefb240e94075a13a6913a4db3a74
Autor:
Yao Zhi, Matthew C. Taylor, Peter M. Campbell, Andrew C. Warden, Pushkar Shrestha, Anna El Tahchy, Vivien Rolland, Thomas Vanhercke, James R. Petrie, Rosemary G. White, Wenli Chen, Surinder P. Singh, Qing Liu
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Lipid droplets (LDs) are composed of a monolayer of phospholipids (PLs), surrounding a core of non-polar lipids that consist mostly of triacylglycerols (TAGs) and to a lesser extent diacylglycerols. In this study, lipidome analysis illustrated striki
Externí odkaz:
https://doaj.org/article/e05ba77c1d934a6dbdd791e04984ba58
Autor:
Chris Greening, Thanavit Jirapanjawat, Shahana Afroze, Blair Ney, Colin Scott, Gunjan Pandey, Brendon M. Lee, Robyn J. Russell, Colin J. Jackson, John G. Oakeshott, Matthew C. Taylor, Andrew C. Warden
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
An unusual aspect of actinobacterial metabolism is the use of the redox cofactor F420. Studies have shown that actinobacterial F420H2-dependent reductases promiscuously hydrogenate diverse organic compounds in biodegradative and biosynthetic processe
Externí odkaz:
https://doaj.org/article/9c3eee481f1c46efab8c6eb800289757