Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Andrew Butterfield"'
Autor:
Edward R. Polanco, Tarek E. Moustafa, Andrew Butterfield, Sandra D. Scherer, Emilio Cortes-Sanchez, Tyler Bodily, Benjamin T. Spike, Bryan E. Welm, Philip S. Bernard, Thomas A. Zangle
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The authors developed a real-time and label-free approach based on quantitative phase imaging to determine drug sensitivity with significant advantages over endpoint viability or metabolic assays, and which reveals single cell response heterogeneity.
Externí odkaz:
https://doaj.org/article/bdafcd4216674d5e8612300cafe2762b
Autor:
Blake R. Wilde, Mohan R. Kaadige, Katrin P. Guillen, Andrew Butterfield, Bryan E. Welm, Donald E. Ayer
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Protein synthesis is regulated by the availability of amino acids, the engagement of growth factor signaling pathways, and adenosine triphosphate (ATP) levels sufficient to support translation. Crosstalk between these inputs is ex
Externí odkaz:
https://doaj.org/article/c974fd6b85e94429a1a2e9d12bfd477a
Autor:
Andrew Butterfield
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 167, Iss Proc. UITP 2014, Pp 14-22 (2014)
We describe a prototype theorem prover, UTP2, developed to match the style of hand-written proof work in the Unifying Theories of Programming semantical framework. This is based on alphabetised predicates in a 2nd-order logic, with a strong emphasis
Externí odkaz:
https://doaj.org/article/fc6b5103b41b4c6592928d33e5420769
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Histone deacetylase (HDAC) inhibition has sporadic clinical efficacy in urothelial carcinoma; the genomic basis for clinical response is not known. In two separate phase I clinical trials testing pharmacokinetic aspects of HDAC inhibitors in advanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec4e1e38652dd7a79529d4ba01a40db4
https://doi.org/10.1158/1535-7163.c.6537834.v1
https://doi.org/10.1158/1535-7163.c.6537834.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
GSEA with Hallmark gene sets performed on transcriptional changes in HT1197 cells treated with panobinostat for 48 hours. A. Top 6 downregulated GSEA signatures B. Top 6 upregulated GSEA signatures C. GSEA HT1197 vs UMUC3 ( comparison of transcriptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3dc70c008073ca019badbdc66ba909
https://doi.org/10.1158/1535-7163.22504713
https://doi.org/10.1158/1535-7163.22504713
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Heat map of top 50 genes affected in HT1197 cells when treated with panobinostat at 48 hours log2 gene expression change(HT1197 A-B and C represent control replicates, HT1197 Pano A, B, C represent treated replicates). For the cell lines with replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a56af42c97fabe3bfcd48fef55e9f8
https://doi.org/10.1158/1535-7163.22504722
https://doi.org/10.1158/1535-7163.22504722
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Individual drug characteristics and doses, maximum plasma levels and protein binding of panobinostat and belinostat in the two phase 1 studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881bc6ec7f2724358ba7b34045aa5295
https://doi.org/10.1158/1535-7163.22504716
https://doi.org/10.1158/1535-7163.22504716
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Study Schema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d03082dfc96e6a789b51e7093790f38
https://doi.org/10.1158/1535-7163.22504728.v1
https://doi.org/10.1158/1535-7163.22504728.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Swimmer Plot to show the best overall response and duration of benefit in seven bladder cancer patients from Table 1 treated with HDAC inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abb7b29048342a29e3e1e00fea1a0e2
https://doi.org/10.1158/1535-7163.22504725.v1
https://doi.org/10.1158/1535-7163.22504725.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Demographic and clinical characteristics of patients treated with belinostat and panobinostat with archived tumor tissue available for study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c198553b1a7942eb81be0ac158350da0
https://doi.org/10.1158/1535-7163.22504719.v1
https://doi.org/10.1158/1535-7163.22504719.v1