Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Andrew Brenner"'
Autor:
Chase Christenson, Chengyue Wu, David A. Hormuth, II, Shiliang Huang, Ande Bao, Andrew Brenner, Thomas E. Yankeelov
Publikováno v:
Brain Multiphysics, Vol 5, Iss , Pp 100084- (2023)
Rhenium-186 (186Re) labeled nanoliposome (RNL) therapy for recurrent glioblastoma patients has shown promise to improve outcomes by locally delivering radiation to affected areas. To optimize the delivery of RNL, we have developed a framework to pred
Externí odkaz:
https://doaj.org/article/1176bf43f8224916b4901975af7a052c
Autor:
Subapriya Rajamanickam, Jun Hyoung Park, Panneerdoss Subbarayalu, Santosh Timilsina, Kaitlyn Bates, Pooja Yadav, Saif S. R. Nirzhor, Vijay Eedunuri, Tabrez A. Mohammad, Kwang Hwa Jung, Benjamin Onyeagucha, Nourhan Abdelfattah, Raymond Benevides, Grace Lee, Yidong Chen, Ratna Vadlamudi, Andrew Brenner, Virginia Kaklamani, Ismail Jatoi, John Kuhn, Robert Hromas, Yogesh K. Gupta, Benny A. Kaipparettu, Jack L. Arbiser, Manjeet K. Rao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
A report of the small molecule Carbazole Blue demonstrates inhibition of breast cancer growth and metastasis without adverse effects on normal tissue.
Externí odkaz:
https://doaj.org/article/7a4cae1b109747c5bf6ef01173eb2df8
Autor:
Bryan McClellan, Tommy Pham, Brittany Harlow, Gabby Lee, Duan Quach, Christopher Jolly, Andrew Brenner, Linda deGraffenried
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 16 (2022)
Purpose: The objective of this study is to determine the impact of exposure to obesity-related systemic factors on fatty acid synthase enzyme (FASN) expression in breast cancer cells. Methods: MCF-7 breast cancer cells were exposed to sera from patie
Externí odkaz:
https://doaj.org/article/fc05823491154e1a92ec210b700f6884
Autor:
Adam Kosti, Patricia Rosa de Araujo, Wei-Qing Li, Gabriela D. A. Guardia, Jennifer Chiou, Caihong Yi, Debashish Ray, Fabiana Meliso, Yi-Ming Li, Talia Delambre, Mei Qiao, Suzanne S. Burns, Franziska K. Lorbeer, Fanny Georgi, Markus Flosbach, Sarah Klinnert, Anne Jenseit, Xiufen Lei, Carolina Romero Sandoval, Kevin Ha, Hong Zheng, Renu Pandey, Aleksandra Gruslova, Yogesh K. Gupta, Andrew Brenner, Erzsebet Kokovay, Timothy R. Hughes, Quaid D. Morris, Pedro A. F. Galante, Stefano Tiziani, Luiz O. F. Penalva
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-32 (2020)
Abstract Background RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiation and growth. Ident
Externí odkaz:
https://doaj.org/article/351c24c3b258441fade10ab7e34c510d
Autor:
Gerald Falchook, Jeffrey Infante, Hendrik-Tobias Arkenau, Manish R. Patel, Emma Dean, Erkut Borazanci, Andrew Brenner, Natalie Cook, Juanita Lopez, Shubham Pant, Arthur Frankel, Peter Schmid, Kathleen Moore, William McCulloch, Katharine Grimmer, Marie O'Farrell, George Kemble, Howard Burris
Publikováno v:
EClinicalMedicine, Vol 34, Iss , Pp 100797- (2021)
Background: We conducted a first-in-human dose-escalation study with the oral FASN inhibitor TVB-2640 to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D), as monotherapy and with a taxane. Methods: This completed open-la
Externí odkaz:
https://doaj.org/article/2febb21dda0b44dcb8507b74f4dd5b16
Autor:
Nourhan Abdelfattah, Subapriya Rajamanickam, Subbarayalu Panneerdoss, Santosh Timilsina, Pooja Yadav, Benjamin C. Onyeagucha, Michael Garcia, Ratna Vadlamudi, Yidong Chen, Andrew Brenner, Peter Houghton, Manjeet K. Rao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
The radiation and chemotherapy used for treating medulloblastoma patients cause debilitating side effects. Here, the authors show that miR-584 acts as a therapeutic adjuvant as it sensitizes medulloblastoma to radiation and chemotherapy by targeting
Externí odkaz:
https://doaj.org/article/7e6b817f247d44dd9e1ce5001fd43f4d
Autor:
William Kelly, Adolfo Enrique Diaz Duque, Joel Michalek, Brandon Konkel, Laura Caflisch, Yidong Chen, Sarath Chand Pathuri, Vinu Madhusudanannair-Kunnuparampil, John Floyd, Andrew Brenner
Publikováno v:
Clinical Cancer Research. :OF1-OF7
Purpose: Glioblastoma represents the most common primary brain tumor. Although antiangiogenics are used in the recurrent setting, they do not prolong survival. Glioblastoma is known to upregulate fatty acid synthase (FASN) to facilitate lipid biosynt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2942e2b8e31dc8727eb3305f95ec388
https://doi.org/10.1158/1078-0432.ccr-22-2807
https://doi.org/10.1158/1078-0432.ccr-22-2807
Publikováno v:
Cancer Research. 83:P1-14
Purpose: Sacituzumab govitecan has shown efficacy and acceptable tolerability in a multicenter phase I/II clinical trial (NCT01631552) in patients with advanced epithelial cancers. Our study was initiated to determine the bioavailability of Sacituzum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c436ab07eb89b862e7185c9061fa1ea
https://doi.org/10.1158/1538-7445.sabcs22-p1-14-04
https://doi.org/10.1158/1538-7445.sabcs22-p1-14-04
Autor:
Andrew Brenner
Publikováno v:
Philosophy of Science. :1-15
I present new counterexamples to the asymmetry of grounding: we have prima facie reason to think that some conditional probabilities partially ground their inverse conditional probabilities, and vice versa. These new counterexamples may require that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc39560f264101de8c2058dc31b2b037
https://doi.org/10.1017/psa.2022.85
https://doi.org/10.1017/psa.2022.85
Autor:
Andrew Brenner, John Floyd, Vinu Madhusudanannair-Kunnuparampil, Sarath Chand Pathuri, Yidong Chen, Laura Caflisch, Brandon Konkel, Joel Michalek, Adolfo Enrique Diaz Duque, William Kelly
Representativeness of Study Participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e609cdfa6edf1ea970dc0868baed67
https://doi.org/10.1158/1078-0432.22787533
https://doi.org/10.1158/1078-0432.22787533
