Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew Boghossian"'
Autor:
Wei Qiu, Qi Sun, Yi Yang, Chirag Patel, Meng Sun, Yue Liu, Kyle Halliwill, Sarah Kim, Rebecca Mathew, Jennifer M Frost, Jennifer A Roth, Domenick Kennedy, Robert T Manguso, Kathleen B Yates, Hakimeh Ebrahimi-Nik, Christina K Baumgartner, Arvin Iracheta-Vellve, Keith M Hamel, Kira Olander, Thomas GR Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Ashwin V Kammula, Audrey J Muscato, Prasanthi Geda, Kelly Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Carey Backus, Angeline Chen, Kenton Longenecker, Joseph Klahn, Cara Hrusch, Navasona Krishnan, Charles W Hutchins, Jacqueline Aguado, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa Ronan, Meng-Ju Wu, Debattama R Sen, Gabriel K Griffin, Nabeel El-Bardeesy, Patricia Trusk, Joshua H Decker, Stacey Fossey, Marcia N Paddock, Elliot P Farney, Clay Beauregard, Philip R Kym
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/11356ff1bf1f4b63ab1324cafa253315
Autor:
Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y. Kim, Xijun Zhu, Andrew Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Stephen M. Hinshaw, Behnam Nabet, Steven M. Corsello, Nicholas Kwiatkowski, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray
Publikováno v:
J Med Chem
Transcriptional enhanced associate domain (TEAD) proteins together with their transcriptional coactivator yes-associated protein (YAP) and transcriptional coactivator with the PDZ-binding motif (TAZ) are important transcription factors and cofactors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad6d58cc21b14e6d0f6ee62852637f6
https://doi.org/10.1021/acs.jmedchem.2c01548
https://doi.org/10.1021/acs.jmedchem.2c01548
Autor:
Matthew G. Rees, Lisa Brenan, Mariana do Carmo, Patrick Duggan, Besnik Bajrami, Michael Arciprete, Andrew Boghossian, Emma Vaimberg, Steven J. Ferrara, Timothy A. Lewis, Danny Rosenberg, Tenzin Sangpo, Jennifer A. Roth, Virendar K. Kaushik, Federica Piccioni, John G. Doench, David E. Root, Cory M. Johannessen
Publikováno v:
Nature Chemical Biology. 18:615-624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ac7ee4182f44347d0a5bf923187d891
https://doi.org/10.1038/s41589-022-00996-7
https://doi.org/10.1038/s41589-022-00996-7
Autor:
Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve, Kira E. Olander, Thomas R.G. Davis, Sarah Y. Kim, Mitchell D. Yeary, James C. Patti, Tyler M. Balon, Omar Ismail Avila, Cun Lan Chuong, Meng-Ju Wu, Christina K. Baumgartner, Keith M. Hamel, Kathleen A. McGuire, Rebecca Mathew, Carey Backus, Ian C. Kohnle, Zhaoming Xiong, Elliot P. Farney, Jennifer M. Frost, Geoff T. Halvorsen, Matthew Rees, Andrew Boghossian, Melissa Ronan, Jennifer A. Roth, Todd R. Golub, Gabriel K. Griffin, Nabeel El-Bardeesy, Clay C. Beauregard, Philip R. Kym, Kathleen B. Yates, Robert T. Manguso
Publikováno v:
Cancer Immunology Research. 10:A41-A41
Immune checkpoint blockade is effective for a subset of patients across many cancers, but most patients are refractory to current immunotherapies and new approaches are needed to overcome resistance. The protein tyrosine phosphatase PTPN2 is a centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f4e8814e7bd29051c6abf0b707bbe5
https://doi.org/10.1158/2326-6074.tumimm22-a41
https://doi.org/10.1158/2326-6074.tumimm22-a41
Autor:
Mohammad H. Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann DeVine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer P. Gale, Rik Derynck, Thomas Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger-Mathason, Anne E. Carpenter
Identifying chemical regulators of biological pathways is currently a time-consuming bottleneck in developing therapeutics and small-molecule research tools. Typically, thousands to millions of candidate small molecules are tested in target-based bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa998708d494bc5bb5f98affb1ae7d3
https://doi.org/10.1101/2021.07.29.454377
https://doi.org/10.1101/2021.07.29.454377
Autor:
Matthew G, Rees, Lisa, Brenan, Mariana, do Carmo, Patrick, Duggan, Besnik, Bajrami, Michael, Arciprete, Andrew, Boghossian, Emma, Vaimberg, Steven J, Ferrara, Timothy A, Lewis, Danny, Rosenberg, Tenzin, Sangpo, Jennifer A, Roth, Virendar K, Kaushik, Federica, Piccioni, John G, Doench, David E, Root, Cory M, Johannessen
Publikováno v:
Nature chemical biology. 18(6)
The ability to understand and predict variable responses to therapeutic agents may improve outcomes in patients with cancer. We hypothesized that the basal gene-transcription state of cancer cell lines, coupled with cell viability profiles of small m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74b3baf371a7ae56e6bed3c5588894f6
https://pubmed.ncbi.nlm.nih.gov/35332332
https://pubmed.ncbi.nlm.nih.gov/35332332
Autor:
Arvin Iracheta-Vellve, Hakimeh Ebrahimi-Nik, Thomas R. Davis, Kira E. Olander, Sarah Y. Kim, Mitchell D. Yeary, James C. Patti, Ian C. Kohnle, Christina K. Baumgartner, Keith M. Hamel, Kathleen A. McGuire, Cun Lan Chuong, Zhaoming Xiong, Elliot P. Farney, Jennifer M. Frost, Matthew Rees, Andrew Boghossian, Melissa Ronan, Jennifer A. Roth, Todd R. Golub, Gabriel K. Griffin, Clay Beauregard, Philip R. Kym, Kathleen B. Yates, Robert T. Manguso
Publikováno v:
Cancer Research. 82:606-606
Immune checkpoint blockade is effective for a subset of patients across many cancers, but most patients are refractory to current immunotherapies and new approaches are needed to overcome resistance. The protein tyrosine phosphatase PTPN2 is a centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41bf1f8f30988b71b649ed6c58e4e9df
https://doi.org/10.1158/1538-7445.am2022-606
https://doi.org/10.1158/1538-7445.am2022-606