Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Andrew Bahn"'
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Stem cells are considered as the next generation drug treatment in patients with cardiovascular disease who are resistant to conventional treatment. Among several stem cells used in the clinical setting, cardiac stem cells (CSCs) which reside in the
Externí odkaz:
https://doaj.org/article/6520e91213a5460781962a292038ee53
Publikováno v:
Antioxidants & Redox Signaling. 36:608-630
Significance: Diabetic heart disease (DHD) is the primary cause of mortality in people with diabetes. A significant contributor to the development of DHD is the disruption of redox balance due to r...
Autor:
Sean Coffey, Michael J.A. Williams, Sweta Kumari, Rajesh Katare, Dominic Parry, Andrew Bahn, Jayanthi Bellae Papannarao, Richard W. Bunton, Dhananjie Chandrasekera, Ramanen Sugunesegran, Philip Davis, Nima Purvis, Isabelle van Hout, Sophie Gandhi
Publikováno v:
Diabetologia. 64:1422-1435
Diabetes mellitus causes a progressive loss of functional efficacy in stem cells, including cardiac progenitor cells (CPCs). The underlying molecular mechanism is still not known. MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate g
Publikováno v:
The FASEB Journal. 35
Autor:
Carol T. Bussey, Gillian Hughes, Andrew Bahn, Patricia A. Cragg, Regis R. Lamberts, Ingrid C. Fomison-Nurse, Rosalind F. Cook
Publikováno v:
Experimental Physiology. 104:808-818
NEW FINDINGS What is the central question of this study? Are there specific contributions of β1 - and β2 -adrenoceptor subtypes to the impaired β-adrenoceptor responsiveness of the type 2 diabetic heart? What is the main finding and its importance
Autor:
Rosalind F, Cook, Carol T, Bussey, Ingrid C, Fomison-Nurse, Gillian, Hughes, Andrew, Bahn, Patricia A, Cragg, Regis R, Lamberts
Publikováno v:
Experimental physiology. 104(6)
What is the central question of this study? Are there specific contributions of βImpaired β-adrenoceptor (β-AR) responsiveness causes cardiac vulnerability in patients with type 2 diabetes, but the independent contributions of β
Publikováno v:
Experimental physiology. 103(8)
NEW FINDINGS What is the central question of the study? Is the reduced signalling of AMP-activated protein kinase (AMPK), a key regulator of energy homeostasis in the heart, responsible for the reduced β-adrenergic responsiveness of the heart in obe
Autor:
Fiona J. McDonald, Ivan A. Sammut, Sama Mugloo, Robert J. Walker, Martin Fronius, Andrew Bahn, Zoe Ashley, Catherine J Leader
Publikováno v:
The FASEB Journal. 32
Autor:
Yimin Yao, Ivan A. Sammut, Andrew Bahn, H. P. Aye Thaung, Carol T. Bussey, Gillian Hughes, Regis R. Lamberts, Peter P. Jones
Publikováno v:
Experimental Physiology. 100:628-639
New Findings What is the central question of this study? Can bilateral renal denervation, an effective antihypertensive treatment in clinical and experimental studies, improve cardiac β-adrenoceptor responsiveness in a diabetic model with underlying
Publikováno v:
Biochemical and Biophysical Research Communications. 452:157-162
Gout patients receiving a combination of allopurinol and furosemide require higher allopurinol doses to achieve the target serum urate (SU) of