Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andrew Bagshaw"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113862 (2014)
To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers. Only a handful of previous reports have evaluated the
Externí odkaz:
https://doaj.org/article/73910df80c1e4facbe07118fe5c86e19
Autor:
Sterling Sawaya, Andrew Bagshaw, Emmanuel Buschiazzo, Pankaj Kumar, Shantanu Chowdhury, Michael A Black, Neil Gemmell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54710 (2013)
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests tha
Externí odkaz:
https://doaj.org/article/cfdeef03ade9437ea46767f92685df6b
Autor:
Neil Gemmell, Andrew Bagshaw
Publikováno v:
Nucleic Acids Research. 51:3261-3269
In recent decades, study of DNA structure has largely been focused on the interrelationships between nucleotides at the level of nearest neighbours. A little-utilized approach to probing structure on a larger scale is non-denaturing bisulfite modific
Publikováno v:
SLEEP. 46:A86-A87
Introduction Sleep is a multiscale phenomenon. It has subjective and objective components often not highly correlated. Given the importance of brain networks for cognition and evidence that sleep deprivation and variability in habitual sleep patterns
Autor:
Conor Bolas, Laurie A. Howe, Scott Peacock, Donald J. Brill, Jing Li, Simona Percec, Andrew Bagshaw
Publikováno v:
Polymer. 54:5754-5761
Oxidative polymerization of pyrrole on the surface of polyimide (PI) films was demonstrated to generate uniform, adherent coatings consisting of polypyrrole (PPy) electro-active nano-domains. This polymerization was carried out in aqueous methanol so
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy. 222:93-102
This paper describes a novel design for reducing secondary flow in turbines. The design builds on previous work on non-axisymmetric profiled endwalls by combining them with three-dimensional blade design. Profiled endwalls have been shown to effectiv
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy. 222:103-110
This paper presents a detailed series of measurements on a novel design for reducing secondary flow in a linear cascade. The design of this geometry, which features profiled endwalls and three-dimensional blade shaping was discussed in a companion pa
Publikováno v:
Volume 4: Heat Transfer, Parts A and B.
This paper shows a method by which the combined CFD-FE analysis process for prediction of aero engine disc temperatures and thermal growths is sped up, with relatively small computational power requirements. The method, known as the temperature influ
Publikováno v:
Volume 6: Turbomachinery, Parts A, B, and C.
Methods to reduce secondary flows and losses in turbines have been studied for many years. This paper presents the latest results from a series of projects using profiled end walls, blade lean and modifying the blade profile near the end wall. In add