Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Andrew B. Kelly"'
Autor:
Andras Gruber, Kenichi A. Tanaka, Andrew B. Kelly, Stephen R. Hanson, José A. Fernández, Mitsunobu Mohri, John H. Griffin, Ulla M. Marzec
Publikováno v:
British Journal of Haematology. 132:197-203
We studied whether there was a relationship between the anticoagulant effects of recombinant human soluble thrombomodulin (rhsTM) and activation of protein C in a primate model of acute vascular graft thrombosis in 11 baboons (Papio species). Baboons
Autor:
Stephen R. Hanson, Nobuyuki Katori, Kenichi A. Tanaka, Andrew B. Kelly, Harry F. Kotze, Ulla M. Marzec
Publikováno v:
Thrombosis Research. 115:79-87
Background The occurrence of thrombocytopenia has been reported during clinical eptifibatide (Integrilin) therapy, but the exact mechanism is not yet established to explain the varied duration and severity of thrombocytopenia associated with glycopro
Autor:
Jeffrey J. Rade, Stephen R. Hanson, Andrew B. Kelly, Johanna Anderson, Laurence A. Harker, Monique M. H. Marijianowski, Anders Lundell
Publikováno v:
Circulation. 100:2018-2024
Background —The hypothesis that thrombin mediates the formation of neointimal vascular lesions at sites of mechanical vascular injury has been tested in baboons by measurement of the effects of hirudin delivered by retrovirus-transduced hirudin-sec
Autor:
Paul G. Yock, Laurence A. Harker, Andrew B. Kelly, Stephen R. Hanson, Neal G. Uren, Peter J. Fitzgerald, Nobuyuki Komiyama, Jonas A. Metz, M.Pauliina Moore, Nicolas A.F. Chronos
Publikováno v:
Ultrasound in Medicine & Biology. 25:561-566
We tested the ability of ultrasound radiofrequency (RF) signal analysis to characterize thrombus accumulation in a Dacron graft incorporated into the exteriorized arteriovenous shunt in 3 baboons with constant blood flow for 60 min. Thrombus formatio
Autor:
J.-M. Herbert, N. R. F. Chronos, Laurence A. Harker, Andrew B. Kelly, Ulla M. Marzec, Stephen R. Hanson, I. B. Sundell
Publikováno v:
Circulation. 98:2461-2469
Background —A recent study showed that clopidogrel reduces thrombo-occlusive complications in patients with symptomatic atherosclerosis more effectively than aspirin. Methods and Results —The effects of clopidogrel and aspirin have been compared,
Autor:
Laurence A. Harker, Ulla M. Marzec, Francis Novembre, I. Birgitta Sundell, Edmund K. Waller, Simon Karpatkin, Harold M. McClure, Andrew B. Kelly, Richard B. Stead
Publikováno v:
Blood. 91:4427-4433
Three chimpanzees experimentally infected with human immunodeficiency virus (HIV) developed significant chronic thrombocytopenia after 5, 4, and 2 years, with peripheral platelet counts averaging 64 ± 19 × 103/μL (P = .004 compared with 228 ± 92
Publikováno v:
Stem Cells. 16:107-119
Endogenous thrombopoietin (TPO) stimulates platelet production in nonhuman primates by inducing dose-dependent megakaryocyte development from early marrow hematopoietic progenitors and subsequent proliferation and endoreduplication. Recombinant human
Autor:
Laurence A. Harker, John D. Hughes, Andrew B. Kelly, Stephen R. Hanson, Alan B. Lumsden, Changyi Chen
Publikováno v:
Journal of Vascular Surgery. 26:87-93
Purpose: Recently, very late antigen-4 (VLA-4) has been shown to mediate initial monocyte adhesion and migration to the injured artery. We hypothesized that blocking monocyte adhesion using a specific monoclonal antibody against VLA-4 may reduce inti
Publikováno v:
Annals of the New York Academy of Sciences. 811:506-514