Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrew B. Gladden"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Endometrial carcinoma (EC) is the most diagnosed gynecological malignancy in Western countries. Both incidence and mortality rates of EC have steadily risen in recent years. Despite generally favorable prognoses for patients with the endometrioid typ
Externí odkaz:
https://doaj.org/article/9c2d4b89702a4c768f234ad58e322c02
Autor:
Vanja Krneta-Stankic, Andrew B. Gladden, Rachel G. Miller, Malgorzata Kloc, Adriana Paulucci-Holthauzen, Mark E. Corkins
SUMMARYE-cadherin junctions facilitate the assembly and disassembly of cell-cell contacts that drive development and homeostasis of epithelial tissues. The stability of E-cadherin-based junctions highly depends on their attachment to the actin cytosk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e15cf277552c391245c063b756e103
https://doi.org/10.1101/2020.08.18.256123
https://doi.org/10.1101/2020.08.18.256123
Autor:
Vanja Krneta-Stankic, Andrew B. Gladden, Malgorzata Kloc, Rachel K. Miller, Adriana Paulucci-Holthauzen, Mark E. Corkins
Publikováno v:
Cell reports
SUMMARY E-cadherin junctions facilitate assembly and disassembly of cell contacts that drive development and homeostasis of epithelial tissues. In this study, using Xenopus embryonic kidney and Madin-Darby canine kidney (MDCK) cells, we investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45aeb055757fd0afef6f8cbceabdb16
https://doi.org/10.1016/j.celrep.2021.109340
https://doi.org/10.1016/j.celrep.2021.109340
Autor:
Vanja Krneta-Stankic, Malgorzata Kloc, Andrew B. Gladden, Pierre D. McCrea, Mark E. Corkins, Rachel K. Miller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221698 (2019)
PLoS ONE, Vol 14, Iss 8, p e0221698 (2019)
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and concentrate waste products into urine. Defects in primary cilia are associated with abnormal formation of nephrons and cyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7656e0687a614f24825d71d54daf962
https://pubmed.ncbi.nlm.nih.gov/31469868
https://pubmed.ncbi.nlm.nih.gov/31469868
Autor:
Rachel K. Miller, Malgorzata Kloc, Andrew B. Gladden, Pierre D. McCrea, Mark E. Corkins, Krneta-Stankic
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and concentrate waste products into urine. Defects in primary cilia are associated with abnormal formation of nephrons and cyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5fe3abe9d22d490ab700826b614e6b
Autor:
Russell Broaddus, Jerry B. Harvey, Andrew B. Gladden, SuSu Xie, Pierre D. McCrea, Luan H. Phan, Katherine C. Kurnit, Jiping Feng, Jessica L. Bowser
Publikováno v:
Clinical Cancer Research. 27:PR005-PR005
Somatic missense mutations in exon 3 of CTNNB1 are associated with significantly worse recurrence-free survival in patients with low grade, early stage endometrioid-type endometrial carcinoma (EEC). CTNNB1 encodes for β-catenin, an integral protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71960e4ea2ec07b6bb9d3fb9466e4dd0
https://doi.org/10.1158/1557-3265.endomet20-pr005
https://doi.org/10.1158/1557-3265.endomet20-pr005
Publikováno v:
Developmental biology. 442(2)
Disruption of endometrial gland formation or function can cause female infertility. Formation of endometrial glands via tubulogenesis of luminal epithelial cells requires the establishment and maintenance of cell polarity and cell adhesion. The FERM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7054c1b42ce08f2bceb36d9ce714497f
https://pubmed.ncbi.nlm.nih.gov/30118662
https://pubmed.ncbi.nlm.nih.gov/30118662
Autor:
Jessica L. Bowser, Russell R. Broaddus, Andrew B. Gladden, Erin Williams, Alejandro Villar-Prados
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189081 (2017)
PLoS ONE, Vol 12, Iss 12, p e0189081 (2017)
Cell adhesion and apicobasal polarity together maintain epithelial tissue organization and homeostasis. Loss of adhesion has been described as a prerequisite for the epithelial to mesenchymal transition. However, what role misregulation of apicobasal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaed6b3f8069cf971f362dc5ade05e5
https://pubmed.ncbi.nlm.nih.gov/29206870
https://pubmed.ncbi.nlm.nih.gov/29206870
Publikováno v:
Genes & Development. 26:2709-2723
The ability to generate asymmetry at the cell cortex underlies cell polarization and asymmetric cell division. Here we demonstrate a novel role for the tumor suppressor Merlin and closely related ERM proteins (Ezrin, Radixin, and Moesin) in generatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35565efa9b09b017c3c06bdf3db776ad
https://doi.org/10.1101/gad.194027.112
https://doi.org/10.1101/gad.194027.112
Autor:
Anil K. Sood, Yiling Lu, Mihai Gagea, Jinsong Liu, John E. Ladbury, Guillermo N. Armaiz Pena, Gordon B. Mills, Charles V. Kingsley, Mikhail Bogdanov, Yong Zhou, Cristina Ivan, Courtney Vallien, Zamal Ahmed, Andrew B. Gladden, Mien Chie Hung, John F. Hancock, Xin Hu, Zahra Timsah, Gabriel Lopez-Berestein, Jonathan Berrout
In the absence of extracellular stimulation the adaptor protein growth factor receptor-bound protein (Grb2) and the phospholipase Plcγ1 compete for the same binding site on fibroblast growth factor receptor 2 (FGFR2). Reducing cellular Grb2 results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c397515c94062908abe4297b261c249
https://eprints.whiterose.ac.uk/89027/1/45329_2_merged_1435083598.pdf
https://eprints.whiterose.ac.uk/89027/1/45329_2_merged_1435083598.pdf