Finding the 'dark matter' in human and yeast protein network prediction and modelling.

Autor: Juan A G Ranea, Ian Morilla, Jon G Lees, Adam J Reid, Corin Yeats, Andrew B Clegg, Francisca Sanchez-Jimenez, Christine Orengo

Publikováno v: PLoS Computational Biology, Vol 6, Iss 9, p e1000945 (2010)

Accurate modelling of biological systems requires a deeper and more complete knowledge about the molecular components and their functional associations than we currently have. Traditionally, new knowledge on protein associations generated by experime

Externí odkaz: https://doaj.org/article/813a90230727425789f66e5449ad6241

Extending CATH: increasing coverage of the protein structure universe and linking structure with function

Autor: Marialuisa Pellegrini-Calace, Robert Rentzsch, Tony E. Lewis, Ian Sillitoe, Nicholas Furnham, David T. Jones, Alison L. Cuff, Christine A. Orengo, Janet M. Thornton, Andrew B. Clegg

Publikováno v: Nucleic Acids Research

CATH version 3.3 (class, architecture, topology, homology) contains 128,688 domains, 2386 homologous superfamilies and 1233 fold groups, and reflects a major focus on classifying structural genomics (SG) structures and transmembrane proteins, both of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd40763c8252a027476bbb7f64b581e8
https://doi.org/10.1093/nar/gkq1001

The EMBRACE web service collection

Autor: Teresa K. Attwood, Philip McDermott, Steve Pettifer, David G. Pisano, Gert Vriend, Edita Bartaseviciute, Inge Jonassen, Dave Thorne, Jon Ison, Kristoffer Rapacki, Jean Salzemann, Matúš Kalaš, Inb Partners, Vincent Breton, Andrew B. Clegg, Olivier Sand, Mahmut Uludag, Heinz Stockinger, Ali Liaquat, Graham Cameron, Maarten L. Hekkelman, Christophe Blanchet, José M. Fernández, Peter Rice, Erik Bongcam-Rudloff, Jose Manuel Rodriguez

Publikováno v: Nucleic Acids Research, 38, W683-8
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2010, 38, pp.W683-W688. ⟨10.1093/nar/gkq297⟩
Nucleic acids research, 38 (SUPPL. 2
Nucleic Acids Research, 2010, 38, pp.W683-W688. ⟨10.1093/nar/gkq297⟩
Pettifer, S, Ison, J, Kalas, M, Thorne, D, McDermott, P, Jonassen, I, Liaquat, A, Fernández, J M, Rodriguez, J M, Partners, INB, Pisano, D G, Blanchet, C, Uludag, M, Rice, P, Bartaseviciute, E, Rapacki, K, Hekkelman, M, Sand, O, Stockinger, H, Clegg, A B, Bongcam-Rudloff, E, Salzemann, J, Breton, V, Attwood, T K, Cameron, G & Vriend, G 2010, ' The EMBRACE web service collection ', Nucleic Acids Research, vol. 38, no. Suppl. 2, pp. W683-W688 . https://doi.org/10.1093/nar/gkq297
Nucleic Acids Research, 38, Web Server issue, pp. W683-8

The EMBRACE (European Model for Bioinformatics Research and Community Education) web service collection is the culmination of a 5-year project that set out to investigate issues involved in developing and deploying web services for use in the life sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b59287f413f6df20826e960a6ee1093
http://hdl.handle.net/2066/89021

An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D

Autor: Andrew J. Martin, Lisa E. M. McMillan, Corin Yeats, Andrew B. Clegg, Anja Barešić, Christine A. Orengo, Jose M. G. Izarzugaza, Alfonso Valencia

Publikováno v: BMC Bioinformatics

Background\ud The phenotypic effects of sequence variations in protein-coding regions come about primarily via their effects on the resulting structures, for example by disrupting active sites or affecting structural stability. In order better to und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cef1857301b2fc9cec6af4868c61fe
http://hdl.handle.net/10044/1/28010

Text Mining

Autor: Andrew B. Clegg, Adrian J. Shepherd

Publikováno v: Bioinformatics ISBN: 9781603274289

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c25fb7a2ce23d547d3c8e27e7ed06d03
https://doi.org/10.1007/978-1-60327-429-6_25