Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andrew B. Bonnell"'
Autor:
Ryan E Pavlovicz, Brandon J Henderson, Andrew B Bonnell, R Thomas Boyd, Dennis B McKay, Chenglong Li
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24949 (2011)
Acetylcholine-based neurotransmission is regulated by cationic, ligand-gated ion channels called nicotinic acetylcholine receptors (nAChRs). These receptors have been linked to numerous neurological diseases and disorders such as Alzheimer's disease,
Externí odkaz:
https://doaj.org/article/9b57c8a5659c42d08cb4510e494a495c
Autor:
R. Thomas Boyd, Dennis B. McKay, Jerad D. Allen, Stephen C. Bergmeier, Andrew B. Bonnell, Crina M. Orac, Tatiana F. González-Cestari, Michael X. Zhu, Chenglong Li, Brandon J. Henderson, Ryan E. Pavlovicz
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 334:761-774
Allosteric modulation of neuronal nicotinic acetylcholine receptors (nAChRs) is considered to be one of the most promising approaches for therapeutics. We have previously reported on the pharmacological activity of several compounds that act as negat