Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Andrew B Goryachev"'
Autor:
Baltazar D Aguda, Andrew B Goryachev
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 9, Pp 1674-1678 (2007)
Externí odkaz:
https://doaj.org/article/3c42505778c241b8bde29b2c2fb71d7d
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 7 (2007)
Externí odkaz:
https://doaj.org/article/cef377c6a7e24373b8dd74550b56e49d
Publikováno v:
PLoS Computational Biology, Vol 2, Iss 12, p e172 (2006)
Formation of multiprotein complexes on cellular membranes is critically dependent on the cyclic activation of small GTPases. FRAP-based analyses demonstrate that within protein complexes, some small GTPases cycle nearly three orders of magnitude fast
Externí odkaz:
https://doaj.org/article/17296fe6c3a945fdb5b4d250c620ca57
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 4, p e37 (2005)
Understanding of the intracellular molecular machinery that is responsible for the complex collective behavior of multicellular populations is an exigent problem of modern biology. Quorum sensing, which allows bacteria to activate genetic programs co
Externí odkaz:
https://doaj.org/article/81482729cb3d4d1b83a28908c10b662c
Autor:
Kirstine Lavrsen, Girish Rajendraprasad, Marcin Leda, Susana Eibes, Elisa Vitiello, Vasileios Katopodis, Andrew B. Goryachev, Marin Barisic
Publikováno v:
Lavrsen, K, Rajendraprasad, G, Leda, M, Eibes, S, Vitiello, E, Katopodis, V, Goryachev, A B & Barisic, M 2023, ' Microtubule detyrosination drives symmetry breaking to polarize cells for directed cell migration ', Proceedings of the National Academy of Sciences, vol. 120, no. 22, e2300322120 . https://doi.org/10.1073/pnas.2300322120
To initiate directed movement, cells must become polarized, establishing a protrusive leading edge and a contractile trailing edge. This symmetry-breaking process involves reorganization of cytoskeleton and asymmetric distribution of regulatory molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4779f9bf9eaf0c087bbbeb95ccf063b
https://www.pure.ed.ac.uk/ws/files/348350550/pnas.2300322120.pdf
https://www.pure.ed.ac.uk/ws/files/348350550/pnas.2300322120.pdf
Autor:
Andrew B. Goryachev
Publikováno v:
Cells, Vol 10, Iss 1, p 86 (2021)
The concept of “symmetry breaking” has become a mainstay of modern biology, yet you will not find a definition of this concept specific to biological systems in Wikipedia [...]
Externí odkaz:
https://doaj.org/article/0fb9d92d7aff449e9b1a5e68e2d5a8a6
Autor:
Jennifer Landino, Marcin Leda, Ani Michaud, Zachary T. Swider, Mariah Prom, Christine M. Field, William M. Bement, Anthony Vecchiarelli, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Biophysical Journal. 122:167a-168a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a533cfa66fd5cbf838a3fc684a37daee
https://doi.org/10.1016/j.bpj.2022.11.1053
https://doi.org/10.1016/j.bpj.2022.11.1053
Autor:
Zachary T. Swider, Ann L. Miller, George von Dassow, Ani Michaud, Andrew B. Goryachev, William M. Bement, Marcin Leda, Jennifer Landino
Publikováno v:
Curr Biol
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
As the interface between the cell and its environment, the cell cortex must be able to respond to a variety of external stimuli. This is made possible in part by cortical excitability, a behavior driven by coupled positive and negative feedback loops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc12fae112c84f59580367eb4d1feaee
https://doi.org/10.1016/j.cub.2021.02.053
https://doi.org/10.1016/j.cub.2021.02.053
Autor:
Ani Michaud, Marcin Leda, Zachary T. Swider, Songeun Kim, Jiaye He, Jennifer Landino, Jenna R. Valley, Jan Huisken, Andrew B. Goryachev, George von Dassow, William M. Bement
Publikováno v:
Michaud, A, Leda, M, Swider, Z T, Kim, S, He, J, Landino, J, Valley, J R, Huisken, J, Goryachev, A B, von Dassow, G & Bement, W M 2022, ' A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2 and RGA-3/4 ', Journal of Cell Biology, vol. 221, no. 8, e202203017 . https://doi.org/10.1083/jcb.202203017
Many cells can generate complementary traveling waves of actin filaments (F-actin) and cytoskeletal regulators. This phenomenon, termed cortical excitability, results from coupled positive and negative feedback loops of cytoskeletal regulators. The n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9b7bae8d5f417516ef7569b70c78e1
https://doi.org/10.1083/jcb.202203017
https://doi.org/10.1083/jcb.202203017
Autor:
Zachary T, Swider, Ani, Michaud, Marcin, Leda, Jennifer, Landino, Andrew B, Goryachev, William M, Bement
Publikováno v:
Molecular biology of the cell. 33(8)
Interest in cortical excitability-the ability of the cell cortex to generate traveling waves of protein activity-has grown considerably over the past 20 years. Attributing biological functions to cortical excitability requires an understanding of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c807c85c5b52fc5ca2bf86b62645a8d2
https://pubmed.ncbi.nlm.nih.gov/35594176
https://pubmed.ncbi.nlm.nih.gov/35594176