Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew B, Kleist"'
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we present the spectrum of genomic alterations in 136 relapsed pediatric AMLs. We identified recurrent exon 13 tandem duplications (TD) in up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6c15e8269161afbfa878da7ad418de
https://doi.org/10.1158/2643-3230.c.6550658.v1
https://doi.org/10.1158/2643-3230.c.6550658.v1
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
Supplementary Data from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61856b4d04dd5ad8020d0a10bd090d6c
https://doi.org/10.1158/2643-3230.22544486
https://doi.org/10.1158/2643-3230.22544486
Autor:
Jeffery M. Klco, Xiaotu Ma, Soheil Meshinchi, Jeffrey E. Rubnitz, Jinghui Zhang, M. Madan Babu, Stanley Pounds, Charles G. Mullighan, James R. Downing, Todd A. Alonzo, Yi-Cheng Wang, Hiroto Inaba, Gang Wu, Michael Rusch, Delaram Rahbarinia, Evadnie Rampersaud, Jason R. Myers, Jonathan Miller, Ryan Hiltenbrand, Ilaria Iacobucci, Evan Parganas, Jenny L. Smith, Rhonda E. Ries, Yen-Chun Liu, Marcus B. Valentine, Virginia Valentine, Huiyun Wu, John Easton, Bengsheng Ju, Amanda R. Leonti, Andrew B. Kleist, Jamie L. Maciaszek, Scott G. Foy, Quang Tran, Pandurang Kolekar, Xiaolong Chen, Yanling Liu, Liqing Tian, Guangchun Song, Michael P. Walsh, Melvin E. Thomas, Juan M. Barajas, Sherif Abdelhamed, Tamara Westover, Kohei Hagiwara, Benjamin J. Huang, Jing Ma, Masayuki Umeda
Supplementary Figure from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3154fb841a9f6b898d586b417fda9168
https://doi.org/10.1158/2643-3230.22544483.v1
https://doi.org/10.1158/2643-3230.22544483.v1
Autor:
Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan M. Barajas, Melvin E. Thomas, Michael P. Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott G. Foy, Jamie L. Maciaszek, Andrew B. Kleist, Amanda R. Leonti, Bengsheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marcus B. Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason R. Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Publikováno v:
Blood Cancer Discov
Blood cancer discovery, vol 3, iss 3
Blood cancer discovery, vol 3, iss 3
The genetics of relapsed pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we present the spectrum of genomic alterations in 136 relapsed pediatric AMLs. We identified recurrent exon 13 tandem duplications (TD) in up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6aa1f38d613f78ebf931b838c22f5db
https://doi.org/10.1158/2643-3230.bcd-21-0160
https://doi.org/10.1158/2643-3230.bcd-21-0160
Autor:
Andrew B. Kleist, Shawn Jenjak, Andrija Sente, Lauren J. Laskowski, Martyna Szpakowska, Maggie M. Calkins, Emilie I. Anderson, Lisa M. McNally, Raimond Heukers, Vladimir Bobkov, Francis C. Peterson, Monica A. Thomas, Andy Chevigné, Martine J. Smit, John D. McCorvy, M. Madan Babu, Brian F. Volkman
Publikováno v:
Kleist, A B, Jenjak, S, Sente, A, Laskowski, L J, Szpakowska, M, Calkins, M M, Anderson, E I, McNally, L M, Heukers, R, Bobkov, V, Peterson, F C, Thomas, M A, Chevigné, A, Smit, M J, McCorvy, J D, Babu, M M & Volkman, B F 2022, ' Conformational selection guides β-arrestin recruitment at a biased G protein–coupled receptor ', Science, vol. 377, no. 6602, pp. 222-228 . https://doi.org/10.1126/science.abj4922
Science
Science, 377(6602), 222-228. American Association for the Advancement of Science
Mol Cell
Science
Science, 377(6602), 222-228. American Association for the Advancement of Science
Mol Cell
G protein–coupled receptors (GPCRs) recruit β-arrestins to coordinate diverse cellular processes, but the structural dynamics driving this process are poorly understood. Atypical chemokine receptors (ACKRs) are intrinsically biased GPCRs that enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f332ddb2bf54ac7f4866ac1e4d21fd39
https://research.vu.nl/en/publications/7f7010df-7f31-4109-8c52-e0d4b931570d
https://research.vu.nl/en/publications/7f7010df-7f31-4109-8c52-e0d4b931570d
Autor:
Constance Baer, Shunsuke Kimura, Mitra S. Rana, Andrew B. Kleist, Tim Flerlage, David J. Feith, Peter Chockley, Wencke Walter, Manja Meggendorfer, Thomas L. Olson, HeeJin Cheon, Kristine C. Olson, Aakrosh Ratan, Martha-Lena Mueller, James M. Foran, Laura J. Janke, Chunxu Qu, Shaina N. Porter, Shondra M. Pruett-Miller, Ravi C. Kalathur, Claudia Haferlach, Wolfgang Kern, Elisabeth Paietta, Paul G. Thomas, M. Madan Babu, Thomas P. Loughran, Ilaria Iacobucci, Torsten Haferlach, Charles G. Mullighan
Publikováno v:
Nature genetics. 54(5)
Chronic lymphoproliferative disorder of natural killer cells (CLPD-NK) is characterized by clonal expansion of natural killer (NK) cells where the underlying genetic mechanisms are incompletely understood. In the present study, we report somatic muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228c0878716efff5e6e286513d8566d4
https://pubmed.ncbi.nlm.nih.gov/35513723
https://pubmed.ncbi.nlm.nih.gov/35513723
Autor:
James M. Foran, Mitra S Rana, Andrew B. Kleist, Martha-Lena Mueller, Claudia Haferlach, David J. Feith, Ravi C. Kalathur, Thomas P. Loughran, Manja Meggendorfer, Aakrosh Ratan, Ilaria Iacobucci, Thomas L. Olson, HeeJin Cheon, Laura J. Janke, Kristine C. Olson, Wencke Walter, Constance Baer, Torsten Haferlach, Elisabeth Paietta, Charles G. Mullighan, M. Madan Babu, Shunsuke Kimura, Wolfgang Kern, Chunxu Qu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S320-S321
Context: Chronic lymphoproliferative disorder of natural killer cells (CLPD-NK) is a subset of large granular lymphocyte (LGL) leukemia included as a provisional entity in the 2016 WHO classification of lymphoid neoplasms, which is characterized by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8045f270f4b49aa384d54ba339e1e995
https://doi.org/10.1016/s2152-2650(21)01754-7
https://doi.org/10.1016/s2152-2650(21)01754-7
Autor:
Brian F. Volkman, Kenneth E. Prehoda, Acacia F. Dishman, Andrew B. Kleist, M. Madan Babu, Francis C. Peterson, Robert C. Tyler, Jamie C. Fox
Publikováno v:
Science (New York, N.Y.). 371(6524)
One sequence encoding two structures Most proteins have stable, folded structures, but there are rare examples of metamorphic proteins that can switch between two different folds that may each have a different function. Dishman et al. investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316c63615f078fe65c38d859da30f43a
https://pubmed.ncbi.nlm.nih.gov/33752957
https://pubmed.ncbi.nlm.nih.gov/33752957
Autor:
Jeffrey E. Rubnitz, Masayuki Umeda, Todd A. Alonzo, Jenny L. Smith, Sherif Abdelhamed, Jamie L. Maciaszek, Michael Rusch, Ilaria Iacobucci, M. Madan Babu, Jinghui Zhang, Pandurang Kolekar, Evadnie Rampersaud, Jing Ma, Guangchun Song, Gang Wu, Jeffery M. Klco, James R. Downing, Hiroto Inaba, Xiaotu Ma, Melvin Edward Thomas, Scott G. Foy, Evan Parganas, Yanling Liu, Yi-Cheng Wang, Marc Valentine, Bensheng Ju, Stanley Pounds, Juan Martin Barajas, Tamara Westover, Quang Tran, Huiyun Wu, Jonathan Miller, Amanda R. Leonti, Benjamin J. Huang, Michael P. Walsh, Virginia Valentine, Rhonda E. Ries, John Easton, Jason Myers, Andrew B. Kleist, Kohei Hagiwara, Delaram Rahbarinia, Xiao-Long Chen, Ryan Hiltenbrand, Soheil Meshinchi, Liqing Tian, Charles G. Mullighan, Yen-Chun Liu
Publikováno v:
Blood. 138:LBA-4
Children with acute myeloid leukemia (AML) have a dismal prognosis due to a high relapse rate; however, the molecular basis leading to relapsed pediatric AML has not yet been fully characterized. To define the spectrum of alterations common at relaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e1cb90fe06946e51c8b28d1368cb091
https://doi.org/10.1182/blood-2021-155134
https://doi.org/10.1182/blood-2021-155134
Autor:
Andrew B, Kleist, Francis, Peterson, Robert C, Tyler, Martin, Gustavsson, Tracy M, Handel, Brian F, Volkman
Publikováno v:
Methods in cell biology. 149
The past decade has witnessed remarkable progress in the determination of G protein-coupled receptor (GPCR) structures, profoundly expanding our understanding of how GPCRs recognize ligands, undergo activation, and interact with intracellular signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c39dfbadfdcdf59e56e7fc0114a14ff7
https://pubmed.ncbi.nlm.nih.gov/30616824
https://pubmed.ncbi.nlm.nih.gov/30616824