Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Andrew A. Stern"'
Autor:
Mengying Xia, Mahboubeh Varmazyad, Iris Pla-Palacín, Dillon C. Gavlock, Richard DeBiasio, Gregory LaRocca, Celeste Reese, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Jacquelyn A. Brown, Lawrence A. Vernetti, Mark Schurdak, Andrew M. Stern, Albert Gough, Jaideep Behari, Alejandro Soto-Gutierrez, D. Lansing Taylor, Mark T. Miedel
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a worldwide health epidemic with a global occurrence of approximately 30%. The pathogenesis of MASLD is a complex, multisystem disorder driven by multiple factors, including genetics
Externí odkaz:
https://doaj.org/article/ee7744aae33d4960a923808275c298d0
Autor:
Shikhar Uttam, Andrew M. Stern, Christopher J. Sevinsky, Samantha Furman, Filippo Pullara, Daniel Spagnolo, Luong Nguyen, Albert Gough, Fiona Ginty, D. Lansing Taylor, S. Chakra Chennubhotla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Spatial information in the tumour microenvironment may be exploited to optimise diagnosis, prognosis and therapy. Here, the authors develop a spatial analytics computational and systems pathology platform (SpAn) based on highly multiplexed antibody i
Externí odkaz:
https://doaj.org/article/a43bb54843794cb1bbe267661f6d6f4c
Autor:
Fangyuan Chen, Qingya Shi, Fen Pei, Andreas Vogt, Rebecca A Porritt, Gustavo Garcia Jr, Angela C Gomez, Mary Hongying Cheng, Mark E Schurdak, Bing Liu, Stephen Y Chan, Vaithilingaraja Arumugaswami, Andrew M Stern, D Lansing Taylor, Moshe Arditi, Ivet Bahar
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 8, Pp n/a-n/a (2021)
Abstract Understanding the mechanism of SARS‐CoV‐2 infection and identifying potential therapeutics are global imperatives. Using a quantitative systems pharmacology approach, we identified a set of repurposable and investigational drugs as poten
Externí odkaz:
https://doaj.org/article/7db43c04a84b4afb9367c079ed650876
Autor:
Daniel E. Lefever, Mark T. Miedel, Fen Pei, Johanna K. DiStefano, Richard Debiasio, Tong Ying Shun, Manush Saydmohammed, Maria Chikina, Lawrence A. Vernetti, Alejandro Soto-Gutierrez, Satdarshan P. Monga, Ramon Bataller, Jaideep Behari, Vijay K. Yechoor, Ivet Bahar, Albert Gough, Andrew M. Stern, D. Lansing Taylor
Publikováno v:
Metabolites, Vol 12, Iss 6, p 528 (2022)
Non-alcoholic fatty liver disease (NAFLD) has a high global prevalence with a heterogeneous and complex pathophysiology that presents barriers to traditional targeted therapeutic approaches. We describe an integrated quantitative systems pharmacology
Externí odkaz:
https://doaj.org/article/465968be7e9348c68b977f1cf547b02f
Autor:
Andrew M. Stern
Publikováno v:
Alzheimer's & Dementia.
Autor:
Andrew M. Stern, Yang Yang, Shanxue Jin, Keitaro Yamashita, Angela L. Meunier, Wen Liu, Yuqi Cai, Maria Ericsson, Lei Liu, Michel Goedert, Sjors H.W. Scheres, Dennis J. Selkoe
Publikováno v:
Neuron.
Autor:
Ian F. Pollack, Andrew M. Stern, Mark E. Schurdak, D. Lansing Taylor, Ansuman Chattopadhyay, Max I. Myers, Stephen C. Mack, Kelsey C. Bertrand, Sameer Agnihotri, Brian Golbourn, Swetha Thambireddy, Daniel R. Premkumar, Esther P. Jane
Supplemental File 2: Genes common to all resistant U87 cell lines compared to drug naive control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f7077cb773aa084ad299586693d6ac
https://doi.org/10.1158/1541-7786.22514064
https://doi.org/10.1158/1541-7786.22514064
Autor:
Ian F. Pollack, Andrew M. Stern, Mark E. Schurdak, D. Lansing Taylor, Ansuman Chattopadhyay, Max I. Myers, Stephen C. Mack, Kelsey C. Bertrand, Sameer Agnihotri, Brian Golbourn, Swetha Thambireddy, Daniel R. Premkumar, Esther P. Jane
Supplemental File 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa56ff9776a3bec668f53c229ce01fd5
https://doi.org/10.1158/1541-7786.22514055
https://doi.org/10.1158/1541-7786.22514055
Autor:
Ian F. Pollack, Andrew M. Stern, Mark E. Schurdak, D. Lansing Taylor, Ansuman Chattopadhyay, Max I. Myers, Stephen C. Mack, Kelsey C. Bertrand, Sameer Agnihotri, Brian Golbourn, Swetha Thambireddy, Daniel R. Premkumar, Esther P. Jane
Supplemental Figure 4. Volcano plot representing differentially expressed genes for U87 naive versus resistant cells with a minimum of a 1.5-fold change, P-value < 0.05 and FDR < 0.10 between control and A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fc6e09dc92a9d4ceb7c99fb2ce7fac
https://doi.org/10.1158/1541-7786.22514082
https://doi.org/10.1158/1541-7786.22514082
Autor:
Ian F. Pollack, Andrew M. Stern, Mark E. Schurdak, D. Lansing Taylor, Ansuman Chattopadhyay, Max I. Myers, Stephen C. Mack, Kelsey C. Bertrand, Sameer Agnihotri, Brian Golbourn, Swetha Thambireddy, Daniel R. Premkumar, Esther P. Jane
Supplemental Figure 1. Schematic of the approach taken to achieve drug resistance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e28665fbf234b5a3b0cd1d5862b6aa
https://doi.org/10.1158/1541-7786.22514091.v1
https://doi.org/10.1158/1541-7786.22514091.v1