Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Andrew A. Renwick"'
Autor:
Sachin Bhusari, George Pugh, Diane R. Stannard, Andrew G. Renwick, Ashley Roberts, David Myers
Publikováno v:
Food and Chemical Toxicology. 153:112236
The developmental neurotoxicity of calcium cyclamate was evaluated in Sprague Dawley [Crl:CD(SD)] rats, administered in drinking water, in comparison to a concurrent control group (water) and a positive control group given propylthiouracil (PTU). Cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43becda4aa470a9516b2fdd6a12683
https://doi.org/10.1016/j.fct.2021.112236
https://doi.org/10.1016/j.fct.2021.112236
Autor:
Andrew G. Renwick
Publikováno v:
international Food Safety handbook ISBN: 9780203750346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d033f1a1af0a3ff6ae3e04fac6049a96
https://doi.org/10.1201/9780203750346-5
https://doi.org/10.1201/9780203750346-5
Autor:
I. Dewhurst, Andrew G. Renwick
Publikováno v:
Regulatory Toxicology and Pharmacology. 65:168-177
Thresholds of Toxicological Concern (TTCs) have been used in the risk assessment of chemicals to which humans are exposed at very low levels. TTC values were developed using data from rodent cancer bioassays and from oral chronic and sub-chronic toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945836f8df7d029cb3580ef4cbe1c089
https://doi.org/10.1016/j.yrtph.2012.03.007
https://doi.org/10.1016/j.yrtph.2012.03.007
Autor:
Andrew G. Renwick, Bernadene A. Magnuson, Michael C. Carakostas, Sylvia P. Poulos, Nadia H. Moore
Publikováno v:
Nutrition reviews. 74(11)
With continued efforts to find solutions to rising rates of obesity and diabetes, there is increased interest in the potential health benefits of the use of low- and no-calorie sweeteners (LNCSs). Concerns about safety often deter the use of LNCSs as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0deb80dd530de6337c93d049ed75c
https://pubmed.ncbi.nlm.nih.gov/27753624
https://pubmed.ncbi.nlm.nih.gov/27753624
Autor:
Andrew G. Renwick, Bette Meek
Publikováno v:
Toxicokinetics and Risk Assessment ISBN: 9780429163746
Chemical-specific adjustment factors (CSAF) provide for the incorporation of quantitative data on interspecies differences or human variability in either toxicokinetics or toxicodynamics to replace appropriately weighted components of default uncerta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0677eaa7f38c51dafda634fd35f92f5f
https://doi.org/10.1201/b14275-2
https://doi.org/10.1201/b14275-2
Autor:
Nicole Cuellar-Kingston, Alex K. Eapen, George Pugh, Rebecca Rogerson, Hua Kern, Christine M. Crincoli, Ashley Roberts, Andrew G. Renwick, Matthew Coffee, Barry Lynch, Sachin Bhusari, Sidd Purkayastha, Michael C. Carakostas
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 79
The acceptable daily intake (ADI) of commercially available steviol glycosides is currently 0–4 mg/kg body weight (bw)/day, based on application of a 100-fold uncertainty factor to a no-observed-adverse-effect-level value from a chronic rat study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9d8e8d13723746f284569fbce407ae
https://pubmed.ncbi.nlm.nih.gov/27181453
https://pubmed.ncbi.nlm.nih.gov/27181453
Autor:
Andrew G. Renwick, Anne Constable, Paolo Mazzatorta, Manuel Dominguez-Estevez, Benoît Schilter
Publikováno v:
Regulatory Toxicology and Pharmacology. 57:247-255
Melamine (MEL) and cyanuric acid (CYA) may occur simultaneously in milk products. There is no health based guidance value for the mixture of MEL + CYA. Limited toxicological data indicate that MEL + CYA toxicity occurs at levels lower than the toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a443e5a751a8fdbd80865cced0dd36e
https://doi.org/10.1016/j.yrtph.2010.03.002
https://doi.org/10.1016/j.yrtph.2010.03.002
Publikováno v:
Food and Chemical Toxicology. 48:S75-S80
Leucomalachite green (LMG) is mutagenic and produces DNA-adducts in vivo, and is carcinogenic in rodent bioassays. Dose-response modelling of the data for hepatocellular adenomas and carcinomas in female mice gave a BMDL10 of 20 mg/kg-bw/day. Limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb2f12ca8e5b760a9c959547dbf01cf
https://doi.org/10.1016/j.fct.2009.09.025
https://doi.org/10.1016/j.fct.2009.09.025
Publikováno v:
Food and Chemical Toxicology. 48:S81-S88
The chlorinated impurities of 1-methylcyclopropene possess weak mutagenicity and are carcinogenic in rodent bioassays. Dose-response modelling of the data for 1-chloro-2-methylpropene gave a BMDL10 for nasal carcinomas in male rats of 11 mg/kg-bw/day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8102f41a3a0d1c3a013f6e7af24142f0
https://doi.org/10.1016/j.fct.2009.09.024
https://doi.org/10.1016/j.fct.2009.09.024
Publikováno v:
Annals of Surgery. 249:402-408
The aim of this study was to determine whether the previously noted poorer survival of men after resection of colorectal cancer varied among clinicopathological tumor stages.The question of whether sex is independently associated with prognosis after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689af8b5529b1cd702ac306df4659143
https://doi.org/10.1097/sla.0b013e31819a0469
https://doi.org/10.1097/sla.0b013e31819a0469