Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Andrew A. Kelso"'
Autor:
Yi-Chang Wang, Andrew A. Kelso, Adak Karamafrooz, Yi-Hsuan Chen, Wei-Kai Chen, Chun-Ting Cheng, Yue Qi, Long Gu, Linda Malkas, Angelo Taglialatela, Hsing-Jien Kung, George-Lucian Moldovan, Alberto Ciccia, Jeremy M. Stark, David K. Ann
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112296- (2023)
Summary: The arginine dependency of cancer cells creates metabolic vulnerability. In this study, we examine the impact of arginine availability on DNA replication and genotoxicity resistance. Using DNA combing assays, we find that limiting extracellu
Externí odkaz:
https://doaj.org/article/02cf18b55c154e37b1ee31164012f9d4
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 364-368 (2017)
This paper contains data related to the research article titled “Characterization of the recombination activities of the Entamoeba histolytica Rad51 recombinase” (Kelso et al., in press) [1]. The known and putative amino acid sequence of Rad51, t
Externí odkaz:
https://doaj.org/article/5832f2ac130042478caa0e655d4a3c22
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A special
Externí odkaz:
https://doaj.org/article/7fdef33e19fe4cfbaa6d6516996391a0
Autor:
Yi-Chang Wang, Andrew A. Kelso, Adak Karamafrooz, Yi-Hsuan Chen, Wei-Kai Chen, Chun-Ting Cheng, Yue Qi, Long Gu, Linda Malkas, Hsing-Jien Kung, George-Lucian Moldovan, Alberto Ciccia, Jeremy M. Stark, David K Ann
Publikováno v:
bioRxiv
SUMMARYThe unique arginine dependencies of cancer cell proliferation and survival creates metabolic vulnerability. Here, we investigate the impact of extracellular arginine availability on DNA replication and genotoxic resistance. Using DNA combing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ed17bf3ba1dadfbd1bebac2bc0a715
https://europepmc.org/articles/PMC9915598/
https://europepmc.org/articles/PMC9915598/
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 364-368 (2017)
Data in Brief
Data in Brief
This paper contains data related to the research article titled “Characterization of the recombination activities of the Entamoeba histolytica Rad51 recombinase” (Kelso et al., in press) [1]. The known and putative amino acid sequence of Rad51, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c70132d5ca4175fa546b2f501e8cfc3
https://doi.org/10.1016/j.dib.2016.12.002
https://doi.org/10.1016/j.dib.2016.12.002
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1999
Homologous recombination is a high-fidelity DNA double-strand break repair pathway that uses a homologous template to repair the break. Recombinases are the central enzymes that facilitate the strand invasion step of homologous recombination, which f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0449c4e87875c43a2414d1a42e41a4c5
https://pubmed.ncbi.nlm.nih.gov/31127584
https://pubmed.ncbi.nlm.nih.gov/31127584
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 8, p e1008319 (2019)
PLoS Genetics, Vol 15, Iss 8, p e1008319 (2019)
Disrupting either the DNA annealing factor RAD52 or the A-family DNA polymerase POLQ can cause synthetic lethality with defects in BRCA1 and BRCA2, which are tumor suppressors important for homology-directed repair of DNA double-strand breaks (DSBs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb1361be7a8600785d63a9eff95ba1f
https://pubmed.ncbi.nlm.nih.gov/31381562
https://pubmed.ncbi.nlm.nih.gov/31381562
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994991
Homologous recombination is a high-fidelity DNA double-strand break repair pathway that uses a homologous template to repair the break. Recombinases are the central enzymes that facilitate the strand invasion step of homologous recombination, which f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a38696bc7542fa0a9681ccdbbdbd60
https://doi.org/10.1007/978-1-4939-9500-4_18
https://doi.org/10.1007/978-1-4939-9500-4_18
Autor:
Audrey Turchick, Yura Bandera, Steven D. Goodson, Michael G. Sehorn, Erin Ratterman, Lesly A. Temesvari, Alexander V. Mazin, Andrew A. Kelso, Stephen H. Foulger, Kristin L. Leskoske, LeAnna L. Ledford, Christopher C. Attaway, Suchitra Chavan, Amanda F. Say, Ada V. King, Deepti Sharma
Publikováno v:
Molecular and Biochemical Parasitology. 210:71-84
The protozoan parasite responsible for human amoebiasis is Entamoeba histolytica. An important facet of the life cycle of E. histolytica involves the conversion of the mature trophozoite to a cyst. This transition is thought to involve homologous rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1835658df818521b85355ee78473ec85
https://doi.org/10.1016/j.molbiopara.2016.09.001
https://doi.org/10.1016/j.molbiopara.2016.09.001
Autor:
Leah E. Watts, Andrew A. Kelso, Amanda F. Say, LeAnna L. Ledford, Shivani B. Shah, J. Nathaniel Diehl, Steven D. Goodson, Michael G. Sehorn, Sarah M. Waldvogel, Julie D. White
Publikováno v:
Nucleic Acids Research
Homologous recombination (HR) is a template-driven repair pathway that mends DNA double-stranded breaks (DSBs), and thus helps to maintain genome stability. The RAD51 recombinase facilitates DNA joint formation during HR, but to accomplish this task,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64bced8ffbd1ad6152cd1e846d14830
https://doi.org/10.1093/nar/gkw877
https://doi.org/10.1093/nar/gkw877