Zobrazeno 1 - 10
of 576
pro vyhledávání: '"Andrew A. Davidson"'
Autor:
Allen Haddrell, Henry Oswin, Mara Otero-Fernandez, Joshua F. Robinson, Tristan Cogan, Robert Alexander, Jamie F. S. Mann, Darryl Hill, Adam Finn, Andrew D. Davidson, Jonathan P. Reid
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract An improved understanding of the underlying physicochemical properties of respiratory aerosol that influence viral infectivity may open new avenues to mitigate the transmission of respiratory diseases such as COVID-19. Previous studies have
Externí odkaz:
https://doaj.org/article/22e7c05e23e2454e8309f6635334e496
Autor:
Joshua T. Armstrong, Lesley P. Bulluck, Andrew T. Davidson, Charles Ryland Stunkle, James R. Vonesh
Publikováno v:
Ecology and Evolution, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Understanding the response of species to global change requires disentangling the drivers of their distributions across landscapes. Colonization and extinction processes, shaped by the interplay of landscape‐level and local patch‐level f
Externí odkaz:
https://doaj.org/article/70925d0af45149d8bb990c071c20a195
Autor:
Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T. Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I’ah Donovan-Banfield, Francisco J. Salguero, Julia A. Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G. Semple, Peter J. M. Openshaw, J. Kenneth Baillie, ISARIC4C Investigators, Stevan R. Emmett, Paul Digard, David A. Matthews, Lance Turtle, Alistair C. Darby, Andrew D. Davidson, Miles W. Carroll, Julian A. Hiscox
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Background The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change in the spike protein,
Externí odkaz:
https://doaj.org/article/b3d75d58548e46f4b79481a60a9b08d2
Autor:
Amy C. Thomas, Elizabeth Oliver, Holly E. Baum, Kapil Gupta, Kathryn L. Shelley, Anna E. Long, Hayley E. Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L. Relton, Ashley Toye, Derek N. Woolfson, Imre Berger, Anu Goenka, Andrew D. Davidson, Kathleen M. Gillespie, Alistair J. K. Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday, the CoMMinS Study Team
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Thomas et al. test 6 ELISAs detecting IgA and IgG antibodies to whole SARS-CoV-2 spike protein, to its receptor binding domain region and to nucleocapsid protein in saliva. Across 20 household outbreaks, antibody responses are heterogeneous, but a re
Externí odkaz:
https://doaj.org/article/55c6b79ee60943e99ecc0c4b2dc196bb
Autor:
Hazel Stewart, Yongxu Lu, Sarah O’Keefe, Anusha Valpadashi, Luis Daniel Cruz-Zaragoza, Hendrik A. Michel, Samantha K. Nguyen, George W. Carnell, Nina Lukhovitskaya, Rachel Milligan, Yasmin Adewusi, Irwin Jungreis, Valeria Lulla, David A. Matthews, Stephen High, Peter Rehling, Edward Emmott, Jonathan L. Heeney, Andrew D. Davidson, James R. Edgar, Geoffrey L. Smith, Andrew E. Firth
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108080- (2023)
Summary: The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative genomic approaches, an additional accessory protein, ORF3c, has been predicted to be encoded within the ORF3a sgmRNA. Expression of ORF3c during infection has
Externí odkaz:
https://doaj.org/article/0eb2381740c24412b7c9b4e912187e2a
Autor:
Marianna Santopaolo, Michaela Gregorova, Fergus Hamilton, David Arnold, Anna Long, Aurora Lacey, Elizabeth Oliver, Alice Halliday, Holly Baum, Kristy Hamilton, Rachel Milligan, Olivia Pearce, Lea Knezevic, Begonia Morales Aza, Alice Milne, Emily Milodowski, Eben Jones, Rajeka Lazarus, Anu Goenka, Adam Finn, Nicholas Maskell, Andrew D Davidson, Kathleen Gillespie, Linda Wooldridge, Laura Rivino
Publikováno v:
eLife, Vol 12 (2023)
Coronavirus disease-19 (COVID-19) causes immune perturbations which may persist long term, and patients frequently report ongoing symptoms for months after recovery. We assessed immune activation at 3–12 months post hospital admission in 187 sample
Externí odkaz:
https://doaj.org/article/ac5579a825a64cf5b124986504c91cb6
Autor:
Peter A C Wing, Nathalie M Schmidt, Rory Peters, Maximilian Erdmann, Rachel Brown, Hao Wang, Leo Swadling, COVIDsortium Investigators, Joseph Newman, Nazia Thakur, Kaho Shionoya, Sophie B Morgan, Timothy Sc Hinks, Koichi Watashi, Dalan Bailey, Scott B Hansen, Andrew D Davidson, Mala K Maini, Jane A McKeating
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011323 (2023)
The severity of disease following infection with SARS-CoV-2 is determined by viral replication kinetics and host immunity, with early T cell responses and/or suppression of viraemia driving a favourable outcome. Recent studies uncovered a role for ch
Externí odkaz:
https://doaj.org/article/e445203a65eb44e382330b64fd988f25
Autor:
A. Sofia F. Oliveira, Deborah K. Shoemark, Amaurys Avila Ibarra, Andrew D. Davidson, Imre Berger, Christiane Schaffitzel, Adrian J. Mulholland
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 139-147 (2022)
The SARS-CoV-2 spike protein is the first contact point between the SARS-CoV-2 virus and host cells and mediates membrane fusion. Recently, a fatty acid binding site was identified in the spike (Toelzer et al. Science 2020). The presence of linoleic
Externí odkaz:
https://doaj.org/article/7a4e5a4ce4ed4c9c9f8922f51cdeada1
Autor:
Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K. Shoemark, A. Sofia F. Oliveira, David A. Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K. N. Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Spatz, Adrian J. Mulholland, Andrew D. Davidson, Christiane Schaffitzel, Imre Berger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
BriSΔ, a SARS-CoV-2 variant from clinical isolate hCoV/England/02/2020, comprises a deletion in a spike cleavage site. The structure and molecular dynamics of this spike provides mechanistic insights into how the deletion modulates virus infectivity
Externí odkaz:
https://doaj.org/article/aca02d9ce50d4ddb8d2a53b3b352d716
Autor:
Alice Halliday, Anna E. Long, Holly E. Baum, Amy C. Thomas, Kathryn L. Shelley, Elizabeth Oliver, Kapil Gupta, Ore Francis, Maia Kavanagh Williamson, Natalie Di Bartolo, Matthew J. Randell, Yassin Ben-Khoud, Ilana Kelland, Georgina Mortimer, Olivia Ball, Charlie Plumptre, Kyla Chandler, Ulrike Obst, Massimiliano Secchi, Lorenzo Piemonti, Vito Lampasona, Joyce Smith, Michaela Gregorova, Lea Knezevic, Jane Metz, Rachael Barr, Begonia Morales-Aza, Jennifer Oliver, Lucy Collingwood, Benjamin Hitchings, Susan Ring, Linda Wooldridge, Laura Rivino, Nicholas Timpson, Jorgen McKernon, Peter Muir, Fergus Hamilton, David Arnold, Derek N. Woolfson, Anu Goenka, Andrew D. Davidson, Ashley M. Toye, Imre Berger, Mick Bailey, Kathleen M. Gillespie, Alistair J. K. Williams, Adam Finn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Low-volume antibody assays can be used to track SARS-CoV-2 infection rates in settings where active testing for virus is limited and remote sampling is optimal. We developed 12 ELISAs detecting total or antibody isotypes to SARS-CoV-2 nucleocapsid, s
Externí odkaz:
https://doaj.org/article/305a69f5b981428bab7c739f99a8b141