Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew Vick"'
Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare—the Case for Surrogate Matrices
Autor:
Evan A, Dubiel, Heather, Myler, Mark E, Arnold, Patrick, Bennett, Jeff, Gatz, Elizabeth, Groeber, Seema, Gupta, Cheikh, Kane, Fumin, Li, William, Mylott, Courtney, Noah, Mark, O'Dell, Eric, Tewalt, Dominic, Warrino, Andrew, Vick
Publikováno v:
The AAPS Journal. 24
The COVID-19 pandemic has strained the biological matrix supply chain. An upsurge in demand driven by numerous COVID-19 therapeutic and vaccine development programs to combat the pandemic, along with logistical challenges sourcing and transporting ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3871bd3e7416d851dccb7bcf2c28c6
https://doi.org/10.1208/s12248-022-00694-1
https://doi.org/10.1208/s12248-022-00694-1
Autor:
Rosie Z Yu, John S Grundy, Scott P Henry, Tae-Won Kim, Daniel A Norris, Jennifer Burkey, Yanfeng Wang, Andrew Vick, Richard S Geary
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Evaluation of species differences and systemic exposure multiples (or ratios) in toxicological animal species versus human is an ongoing exercise during the course of drug development. The systemic exposure ratios are best estimated by directly compa
Externí odkaz:
https://doaj.org/article/246f1041032e42dfa83f03452a855de3
Autor:
Vasileios Kontogiannis, Yuhe Wei, Jamal Rahmani, Yu Zhang, Hui Chen, Zhifang Xiao, Shamma Jauaan Almuhairi, Hui Deng, Akshaya Srikanth Bhagavathula, KunWei Wang, Paul M. Ryan, Minyan Dang, Andrew Vick
Publikováno v:
Phytotherapy research : PTRREFERENCES. 34(6)
Water-soluble dietary fibers have been shown to improve lipid profile and glucose metabolism in diabetes. The aim of this study was to review the effects of psyllium consumption on weight, body mass index, lipid profiles, and glucose metabolism in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b548f468c740c9ee5e378a1f0e8cbe1
https://pubmed.ncbi.nlm.nih.gov/31919936
https://pubmed.ncbi.nlm.nih.gov/31919936
Publikováno v:
Drug Development and Industrial Pharmacy. 42:1334-1339
The objective of this study was to utilize physiologically relevant dynamic dissolution testing with the TNO intestinal model (TIM-1) in vitro gastrointestinal model to investigate the bioaccessibility of celecoxib. A single 200-mg dose of celecoxib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4316624d49e3c014eb4e03e8545ea8
https://doi.org/10.3109/03639045.2015.1135935
https://doi.org/10.3109/03639045.2015.1135935
Publikováno v:
The Journal of Clinical Pharmacology. 54:1125-1133
AMG 416 is a novel peptide agonist of the calcium-sensing receptor. In support of the clinical development program, a pharmacokinetic (PK)/pharmacodynamic (PD) model was developed to describe the relationship between plasma AMG 416 levels and serum i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c28865bde3f65168dfb14a0ab603d3
https://doi.org/10.1002/jcph.314
https://doi.org/10.1002/jcph.314
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 39:251-262
A mathematical absorption model (e.g. transit compartment model) is useful to describe complex absorption process. However, in such a model, an assumption has to be made to introduce multiple doses that a prior dose has been absorbed nearly completel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6290440dc1d8eada31daa8afeffb8189
https://doi.org/10.1007/s10928-012-9247-3
https://doi.org/10.1007/s10928-012-9247-3
Autor:
Tae-Won Kim, Daniel A. Norris, Jennifer Burkey, Rosie Z. Yu, Scott P. Henry, Yanfeng Wang, John S. Grundy, Andrew Vick, Richard S. Geary
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Evaluation of species differences and systemic exposure multiples (or ratios) in toxicological animal species versus human is an ongoing exercise during the course of drug development. The systemic exposure ratios are best estimated by directly compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaba246cfba58550f1f93bdf1ec8253
http://www.sciencedirect.com/science/article/pii/S2162253116300026
http://www.sciencedirect.com/science/article/pii/S2162253116300026
Autor:
Jun, Shen, Jim, Xiao, Karen, Pickthorn, Saling, Huang, Gregory, Bell, Andrew, Vick, Ping, Chen
Publikováno v:
Journal of clinical pharmacology. 54(10)
AMG 416 is a novel peptide agonist of the calcium-sensing receptor. In support of the clinical development program, a pharmacokinetic (PK)/pharmacodynamic (PD) model was developed to describe the relationship between plasma AMG 416 levels and serum i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2006fe8dfa7d5d1f7ce770088645a263
https://pubmed.ncbi.nlm.nih.gov/24752908
https://pubmed.ncbi.nlm.nih.gov/24752908
