Výsledky vyhledávání - "Andrew, Whittaker"

Akademický článek

Doing public health differently: How can public health departments engage with local communities through social media interventions?

Autor: Megan Watkins, Jaimee S. Mallion, Daniel Frings, Jane Wills, Susie Sykes, Andrew Whittaker

Publikováno v: Public Health in Practice, Vol 6, Iss , Pp 100412- (2023)

Objectives: This paper evaluates a collaborative intervention between public health professionals and local social media administrators, in which the social media site Facebook was used with a view to strengthening engagement with and, dissemination

Externí odkaz: https://doaj.org/article/80d0549b13bc49d0bf211e5fa3739f5b

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Akademický článek

11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

Glucocorticoids prescribed to limit inflammation, have significant adverse effects. Here the authors show that co-administration of AZD4017 with prednisolone in men is a potential strategy to limit adverse glucocorticoid effects.

Externí odkaz: https://doaj.org/article/d5729cc721e9453cb5043aab11c131a3

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Akademický článek

Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial

Autor: Iain B. Squire, Anders Gabrielsen, Peter J. Greasley, Linda Wernevik, Judith Hartleib‐Geschwindner, Julie Holden, Susanne Johansson, Anna Rudvik, José Sánchez, Krister Bamberg, Johanna Melin, Andrew Whittaker

Publikováno v: Clinical and Translational Science, Vol 15, Iss 10, Pp 2493-2504 (2022)

Abstract This phase Ib study compared the effects of AZD9977, a selective mineralocorticoid receptor modulator with predicted low hyperkalemia risk, with spironolactone on serum potassium (sK+) in patients with heart failure (HF) with preserved or mi

Externí odkaz: https://doaj.org/article/2c5d085dcf634af18af1d476fc6a3cbd

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Akademický článek

Public health messages during a global emergency through an online community: a discourse and sentiment analysis

Autor: Megan Watkins, Jaimee S. Mallion, Daniel Frings, Jane Wills, Susie Sykes, Andrew Whittaker

Publikováno v: Frontiers in Digital Health, Vol 5 (2023)

The growing popularity of social media and its ubiquitous presence in our lives brings associated risks such as the spread of mis- and disinformation, particularly when these may be unregulated in times of global crises. Online communities are able t

Externí odkaz: https://doaj.org/article/0e0605b5dfc34fe9bba353a55c1e1680

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Akademický článek

Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP)

Autor: Bernard J. Smilde, Clemens Stockklausner, Richard Keen, Andrew Whittaker, Alex N. Bullock, Annette von Delft, Natasja M. van Schoor, Paul B. Yu, E. Marelise W. Eekhoff

Publikováno v: BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)

Abstract Background Fibrodysplasia Ossificans Progressiva (FOP) is a genetic, progressive and devastating disease characterized by severe heterotopic ossification (HO), loss of mobility and early death. There are no FDA approved medications. The STOP

Externí odkaz: https://doaj.org/article/fdc788d39fcf447e80cb3cacd3eed9c2

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Akademický článek

Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study

Autor: Andrew Whittaker, Åsa M. Kragh, Judith Hartleib‐Geschwindner, Muna Albayaty, Anna Backlund, Peter J. Greasley, Maria Heijer, Magnus Kjaer, Pablo Forte, Robert Unwin, Linda Wernevik, Hans Ericsson

Publikováno v: Clinical and Translational Science, Vol 13, Iss 2, Pp 275-283 (2020)

Excessive activation of the mineralocorticoid receptor (MR) underlies the pathophysiology of heart failure and chronic kidney disease. Hyperkalemia risk limits the therapeutic use of conventional MR antagonists. AZD9977 is a nonsteroidal, selective M

Externí odkaz: https://doaj.org/article/abbe228f9fec463ba026031576eb8346

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Making Sense of Risk: Social Work at the Boundary between Care and Control

Autor: Ravit Alfandari, Brian J Taylor, Mary Baginsky, Jim Campbell, Duncan Helm, Campbell Killick, Paul Mccafferty, Judith Mullineux, Jane Shears, Alessandro Sicora, Andrew Whittaker

Publikováno v: Health, Risk & Society. 25:75-92

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e8684b02574aa2c4fc0ef685131f285
https://doi.org/10.1080/13698575.2022.2147904

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Group decision-making theories for child and family social work

Autor: Ravit Alfandari, Brian J. Taylor, Guy Enosh, Campbell Killick, Paul McCafferty, Judith Mullineux, Jarosław Przeperski, Michael Rölver, Andrew Whittaker

Publikováno v: Alfandari, R, Taylor, B J, Enosh, G, Killick, C, McCafferty, P, Mullineux, J, Przeperski, J, Rölver, M & Whittaker, A 2022, ' Group Decision-Making Theories for Child and Family Social Work ', European Journal of Social Work . https://doi.org/10.1080/13691457.2021.2016651

There is increasing interest in decision making in social work. Much of the attention has been on individual professional judgement rather than on group decisions processes. This paper outlines key theoretical approaches from diverse fields of knowle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754923079b1eb8b838967d92e2a89f8c
https://doi.org/10.1080/13691457.2021.2016651

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